22 Publications
2022
Age-dependent formation of TMEM106B amyloid filaments in human brains
Schweighauser, Manuel⋅Schweighauser, Manuel⋅Arseni, Diana⋅Arseni, Diana⋅Bacioglu, Mehtap⋅Bacioglu, Mehtap⋅Huang, Melissa⋅Huang, Melissa⋅Lövestam, Sofia⋅Lövestam, Sofia⋅Shi, Yang⋅Shi, Yang⋅Yang, Yang⋅Yang, Yang⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Kotecha, Abhay⋅Kotecha, Abhay⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Hallinan, Grace I⋅Hallinan, Grace I⋅Newell, Kathy L⋅Newell, Kathy L⋅Tarutani, Airi⋅Tarutani, Airi⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Miyazaki, Masayuki⋅Miyazaki, Masayuki⋅Saito, Yuko⋅Saito, Yuko⋅Yoshida, Mari⋅Yoshida, Mari⋅Hasegawa, Kazuko⋅Hasegawa, Kazuko⋅Lashley, Tammaryn⋅Lashley, Tammaryn⋅Revesz, Tamas⋅Revesz, Tamas⋅Kovacs, Gabor G⋅Kovacs, Gabor G⋅van Swieten, John⋅van Swieten, John⋅Takao, Masaki⋅Takao, Masaki⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Spillantini, Maria Grazia⋅Spillantini, Maria G⋅Ryskeldi-Falcon, Benjamin⋅Ryskeldi-Falcon, Benjamin⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H and Scheres, Sjors H W
Nature, vol. 605, (no. 7909), pp. 310-3,314A-314N, May 12, 2022. | Journal Article
2021
Structure-based classification of tauopathies
Shi, Yang⋅Zhang, Wenjuan⋅Yang, Yang⋅Murzin, Alexey G⋅Falcon, Benjamin⋅Kotecha, Abhay⋅van Beers, Mike⋅Beers, M⋅Tarutani, Airi⋅Kametani, Fuyuki⋅Garringer, Holly J⋅Vidal, Ruben⋅Hallinan, Grace I⋅Lashley, Tammaryn⋅Saito, Yuko⋅Murayama, Shigeo⋅Yoshida, Mari⋅Tanaka, Hidetomo⋅Kakita, Akiyoshi⋅Ikeuchi, Takeshi⋅Robinson, Andrew C⋅Mann, David M⋅Kovacs, Gabor G⋅Revesz, Tamas⋅Ghetti, Bernardino⋅Hasegawa, Masato⋅Goedert, Michel and Scheres, Sjors H
Nature, vol. 598, (no. 7880), pp. 359-3,363A-363M, Oct 14, 2021. | Journal Article
 
Structure of Tau filaments in Prion protein amyloidoses
Hallinan, Grace I⋅Hallinan, Grace I⋅Hallinan, Grace I⋅Hoq, Md Rejaul⋅Hoq, Md Rejaul⋅Ghosh, Manali⋅Ghosh, Manali⋅Vago, Frank S⋅Vago, Frank S⋅Vago, Frank S⋅Fernandez, Anllely⋅Fernandez, Anllely⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Jiang, Wen⋅Jiang, Wen⋅Jiang, Wen⋅Ghetti, Bernardino and Ghetti, Bernardino
Acta Neuropathologica, vol. 142, (no. 2), pp. 227-241, Aug 2021. | Journal Article
2020
Novel tau filament fold in corticobasal degeneration
Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Tarutani, Airi⋅Tarutani, Airi⋅Tarutani, Airi⋅Tarutani, Airi⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Shi, Yang⋅Shi, Yang⋅Shi, Yang⋅Shi, Yang⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H W⋅Scheres, Sjors H⋅Scheres, Sjors H W and Scheres, Sjors H W
Nature, vol. 580, (no. 7802), pp. 283-287,287C,287A-287B,287D-287L, Apr 9, 2020. | Journal Article
2019
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Crowther, R A⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H⋅Scheres, Sjors H W⋅Scheres, Sjors H W and Scheres, Sjors H W
Nature, vol. 568, (no. 7752), pp. 420-3,423A-423K, Apr 18, 2019. | Journal Article
 
Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy
You, Yingjian⋅You, Yingjian⋅You, Yingjian⋅Perkins, Abigail⋅Perkins, Abigail⋅Perkins, Abigail⋅Cisternas, Pablo⋅Cisternas, Pablo⋅Cisternas, Pablo⋅Muñoz, Braulio⋅Muñoz, Braulio⋅Muñoz, Braulio⋅Taylor, Xavier⋅Taylor, Xavier⋅Taylor, Xavier⋅You, Yanwen⋅You, Yanwen⋅You, Yanwen⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Oblak, Adrian L⋅Oblak, Adrian L⋅Oblak, Adrian L⋅Atwood, Brady K⋅Atwood, Brady K⋅Atwood, Brady K⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Lasagna-Reeves, Cristian A⋅Lasagna-Reeves, Cristian A and Lasagna-Reeves, Cristian A
Acta neuropathologica communications, vol. 7, (no. 1), pp. 26, 2019-02-26. | Journal Article
2018
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Schweighauser, Manuel⋅Schweighauser, Manuel⋅Schweighauser, Manuel⋅Murzin, Alexey⋅Murzin, Alexey⋅Murzin, Alexey⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Garringer, Holly⋅Garringer, Holly⋅Garringer, Holly⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Scheres, Sjors⋅Scheres, Sjors⋅Scheres, Sjors⋅Goedert, Michel⋅Goedert, Michel and Goedert, Michel
Acta Neuropathologica, vol. 136, (no. 5), pp. 708, 20181100. | Journal Article
2017
Cryo-EM structures of Tau filaments from Alzheimer’s disease brain
Fitzpatrick, Anthony W P⋅Fitzpatrick, Anthony W. P⋅Fitzpatrick, Anthony W P⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅He, Shaoda⋅He, Shaoda⋅He, Shaoda⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murshudov, Garib⋅Murshudov, Garib⋅Murshudov, Garib⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Crowther, R. Anthony⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H. W⋅Scheres, Sjors H W and Scheres, Sjors H W
Nature, vol. 547, (no. 7662), pp. 190, 2017-07-01. | Journal Article
2016
Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy
Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Irimia, Jose M⋅Irimia, Jose M⋅Irimia, Jose M⋅Li, Wei⋅Li, Wei⋅Li, Wei⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Richine, Briana⋅Richine, Briana⋅Richine, Briana⋅Acton, Anthony⋅Acton, Anthony⋅Acton, Anthony⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 11, (no. 8), pp. e0161341, 2016-00-00. | Journal Article
2015
Systemic and Cerebral Iron Homeostasis in Ferritin Knock-Out Mice
Li, Wei⋅Li, Wei⋅Garringer, Holly J⋅Garringer, Holly J⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Richine, Briana⋅Richine, Briana⋅Acton, Anthony⋅Acton, Anthony⋅VanDuyn, Natalia⋅VanDuyn, Natalia⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Irimia-Dominguez, Jose⋅Irimia-Dominguez, Jose⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Peacock, Munro⋅Peacock, Munro⋅Nass, Richard⋅Nass, Richard⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 10, (no. 1), pp. e0117435, 2015-00-00. | Journal Article
2014
A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation
Nishida, Katsuya⋅Nishida, Katsuya⋅Garringer, Holly⋅Garringer, Holly J⋅Futamura, Naonobu⋅Futamura, Naonobu⋅Funakawa, Itaru⋅Funakawa, Itaru⋅Jinnai, Kenji⋅Jinnai, Kenji⋅Vidal, Ruben⋅Vidal, Ruben⋅Takao, Masaki and Takao, Masaki
Journal of the Neurological Sciences, vol. 342, (no. 1), pp. 177, 2014. | Journal Article
2013
Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice
Garringer, Holly⋅Garringer, Holly J⋅Murrell, Jill⋅Murrell, Jill⋅Sammeta, Neeraja⋅Sammeta, Neeraja⋅Gnezda, Anita⋅Gnezda, Anita⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 8, (no. 2), pp. e56426, 2013-00-00. | Journal Article
2010
Modeling familial British and Danish dementia
Garringer, Holly J⋅Garringer, Holly J⋅Murrell, Jill R⋅Murrell, Jill⋅D'Adamio, Luciano⋅D'Adamio, Luciano⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben G
Brain structure & function, vol. 214, (no. 2-3), pp. 244, 2010-Mar. | Journal Article
2008
Molecular genetic and biochemical analyses of FGF23 mutations in familial tumoral calcinosis
Garringer, Holly⋅Garringer, Holly⋅Malekpour, Mahdi⋅Malekpour, Mahdi⋅Esteghamat, Fatemehsadat⋅Esteghamat, Fatemehsadat⋅Mortazavi, Seyed⋅Mortazavi, Seyed M⋅Davis, Siobhan I⋅Davis, Siobhan⋅Farrow, Emily⋅Farrow, Emily G⋅Yu, Xijie⋅Yu, Xijie⋅Arking, Dan E⋅Arking, Dan⋅Dietz, Harry⋅Dietz, Harry C⋅White, Kenneth E and White, Kenneth
American Journal of Physiology - Endocrinology And Metabolism, vol. 295, (no. 4), pp. 937, 2008-10-01. | Journal Article
 
Molecular genetic and biochemical analyses of FGF23 mutations in familial tumoral calcinosis.(fibroblast growth factor)(Author abstract)
Malekpour, Mahdi⋅Esteghamat, Fatemehsadat⋅Arking, Dan⋅Mortazavi, Seyed⋅Yu, Xijie⋅Davis, Siobhan⋅Farrow, Emily⋅Dietz, Harry⋅White, Kenneth⋅Malekpour, Mahdi⋅Esteghamat, Fatemehsadat⋅Arking, Dan⋅Garringer, Holly⋅Mortazavi, Seyed⋅Yu, Xijie⋅Davis, Siobhan⋅Farrow, Emily⋅Dietz, Harry⋅White, Kenneth and Garringer, Holly
The American Journal of Physiology, vol. 295, (no. 4), pp. E929, 20081001. | Journal Article
 
Tumoral Calcinosis
Brown, Whitney W⋅McCormick, Kenneth L⋅White, Kenneth E⋅Garringer, Holly J and Farrow, Emily G
The Endocrinologist, vol. 18, (no. 4), pp. 194, 2008-07-00. | Journal Article
2007
Phenotypic spectrum of mosaic trisomy 18: Two new patients, a literature review, and counseling issues
Tucker, Megan E⋅Garringer, Holly J and Weaver, David D
American Journal of Medical Genetics Part A, vol. 143A, (no. 5), pp. 517, 1 March 2007. | Journal Article
 
Two novel GALNT3 mutations in familial tumoral calcinosis
Garringer, Holly⋅Garringer, Holly J⋅Mortazavi, Seyed Mohammad Javad⋅Mortazavi, Seyed M⋅Esteghamat, Fatemehsadat⋅Esteghamat, Fatemehsadat⋅Malekpour, Mahdi⋅Malekpour, Mahdi⋅Boztepe, Harika⋅Boztepe, Harika⋅Tanakol, Refik⋅Tanakol, Refik⋅Davis, Siobhan I⋅Davis, Siobhan I⋅White, Kenneth E and White, Kenneth E
American Journal of Medical Genetics Part A, vol. 143A, (no. 20), pp. 2396, 15 October 2007. | Journal Article
2006
Hearing Impairment Susceptibility in Elderly Men and the DFNA18 Locus
Garringer, Holly J⋅Garringer, Holly J⋅Pankratz, Nathan D⋅Pankratz, Nathan⋅Nichols, William C⋅Nichols, William C⋅Reed, Terry E and Reed, Terry
Archives of Otolaryngology–Head & Neck Surgery, vol. 132, (no. 5), pp. 510, 2006-05-01. | Journal Article
 
The Role of Mutant UDP-N-Acetyl-α-d-Galactosamine-Polypeptide N-Acetylgalactosaminyltransferase 3 in Regulating Serum Intact Fibroblast Growth Factor 23 and Matrix Extracellular Phosphoglycoprotein in Heritable Tumoral Calcinosis
Garringer, Holly J⋅Garringer, Holly J⋅Fisher, Corinne⋅Fisher, Corinne⋅Larsson, Tobias E⋅Larsson, Tobias E⋅Davis, Siobhan I⋅Davis, Siobhan I⋅Koller, Daniel L⋅Koller, Daniel L⋅Cullen, Michael J⋅Cullen, Michael J⋅Draman, Mohamad S⋅Draman, Mohamad S⋅Conlon, Niamh⋅Conlon, Niamh⋅Jain, Alka⋅Jain, Alka⋅Fedarko, Neal S⋅Fedarko, Neal S⋅Dasgupta, Bhaskar⋅Dasgupta, Bhaskar⋅White, Kenneth E and White, Kenneth E
The Journal of Clinical Endocrinology & Metabolism, vol. 91, (no. 10), pp. 4042, 2006-10. | Journal Article
2005
Analysis of the Biochemical Mechanisms for the Endocrine Actions of Fibroblast Growth Factor-23
Yu, Xijie⋅Yu, Xijie⋅Ibrahimi, Omar A⋅Ibrahimi, Omar A⋅Goetz, Regina⋅Goetz, Regina⋅Zhang, Fuming⋅Zhang, Fuming⋅Davis, Siobhan I⋅Davis, Siobhan I⋅Garringer, Holly⋅Garringer, Holly J⋅Linhardt, Robert J⋅Linhardt, Robert J⋅Ornitz, David M⋅Ornitz, David⋅Mohammadi, Moosa⋅Mohammadi, Moosa⋅White, Kenneth E and White, Kenneth E
Endocrinology, vol. 146, (no. 11), pp. 4656, 2005-11. | Journal Article
 
Fibroblast Growth Factor-23 Mutants Causing Familial Tumoral Calcinosis Are Differentially Processed
Larsson, Tobias⋅Larsson, Tobias⋅Davis, Siobhan I⋅Davis, Siobhan I⋅Garringer, Holly⋅Garringer, Holly J⋅Mooney, Sean D⋅Mooney, Sean D⋅Draman, Mohamad S⋅Draman, Mohamad S⋅Cullen, Michael J⋅Cullen, Michael J⋅White, Kenneth E and White, Kenneth E
Endocrinology, vol. 146, (no. 9), pp. 3891, 2005-09. | Journal Article