101 Publications (Page 1 of 5)
2023
A multiscale model of pulmonary micrometastasis and immune surveillance: towards cancer patient digital twins
 
An agent-based modeling approach for lung fibrosis in response to COVID-19. PLOS Computational Biology
. | Journal Article
 
PhysiCell Studio: a graphical tool to make agent-based modeling more accessible
2022
A model of multicellular communication mediated through extracellular matrix microstructure
 
An agent-based modeling approach for lung fibrosis in response to COVID-19
 
Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation.
Stahlberg, Eric AStahlberg, Eric A.Stahlberg, Eric AAbdel-Rahman, MohamedAbdel-Rahman, MohamedAbdel-Rahman, MohamedAguilar, BorisAguilar, BorisAguilar, BorisAsadpoure, AlirezaAsadpoure, AlirezaAsadpoure, AlirezaBeckman, Robert ABeckman, Robert ABeckman, Robert A.Borkon, Lynn LBorkon, Lynn L.Borkon, Lynn LBryan, Jeffrey N.Bryan, Jeffrey NBryan, Jeffrey NCebulla, Colleen MCebulla, Colleen MCebulla, Colleen M.Chang, Young HwanChang, Young HwanChang, Young HwanChatterjee, AnsuChatterjee, AnsuChatterjee, AnsuDeng, JunDeng, JunDeng, JunDolatshahi, SepidehDolatshahi, SepidehDolatshahi, SepidehGevaert, OlivierGevaert, OlivierGevaert, OlivierGreenspan, Emily J.Greenspan, Emily JGreenspan, Emily JHao, WenruiHao, WenruiHao, WenruiHernandez-Boussard, TinaHernandez-Boussard, TinaHernandez-Boussard, TinaJackson, Pamela R.Jackson, Pamela RJackson, Pamela RKuijjer, MariekeKuijjer, MariekeKuijjer, MariekeLee, AdrianLee, AdrianLee, AdrianMacklin, PaulMacklin, PaulMacklin, PaulMadhavan, SubhaMadhavan, SubhaMadhavan, SubhaMcCoy, Matthew D.McCoy, Matthew DMcCoy, Matthew DMohammad Mirzaei, NavidMohammad Mirzaei, NavidMohammad Mirzaei, NavidRazzaghi, TalayehRazzaghi, TalayehRazzaghi, TalayehRocha, Heber LRocha, Heber LRocha, Heber L.Shahriyari, LeiliShahriyari, LeiliShahriyari, LeiliShmulevich, IlyaShmulevich, IlyaShmulevich, IlyaStover, Daniel GStover, Daniel GStover, Daniel G.Sun, YiSun, YiSun, YiSyeda-Mahmood, TanveerSyeda-Mahmood, TanveerSyeda-Mahmood, TanveerWang, JinhuaWang, JinhuaWang, JinhuaWang, QiWang, QiWang, QiZervantonakis, IoannisZervantonakis, Ioannis and Zervantonakis, Ioannis
Frontiers in digital health, vol. 4, pp. 1007784, 2022. | Journal Article
 
PhysiCell training apps: Cloud hosted open-source apps to learn cell-based simulation software
Sundus, AneequaKurtoglu, FurkanKonstantinopoulos, KaliChen, MaryWillis, DrewHeiland, Randy and Macklin, Paul
Cold Spring Harbor Laboratory
 
Supporting Computational Apprenticeship Through Educational and Software Infrastructure: A Case Study in a Mathematical Oncology Research Lab.
Madamanchi, AasakiranMadamanchi, AasakiranThomas, MadisonThomas, MadisonMagana, AlejandraMagana, AlejandraHeiland, RandyHeiland, RandyMacklin, Paul and Macklin, Paul
PRIMUS : problems, resources, and issues in mathematics undergraduate studies, vol. 32, (no. 3 Pt 2), pp. 446-467, 2022. | Journal Article
2021
A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling.
Rocha, Heber LGodet, InêsKurtoglu, FurkanMetzcar, JohnKonstantinopoulos, KaliBhoyar, SoumitraGilkes, Daniele M and Macklin, Paul
iScience, vol. 24, (no. 9), pp. 102935, September 24, 2021. | Journal Article
 
A persistent invasive phenotype in post-hypoxic tumor cells is revealed by novel fate-mapping and computational modeling
Rocha, Heber LRocha, H.L.Godet, I.Godet, InêsKurtoglu, FurkanKurtoglu, F.Metzcar, J.Metzcar, JohnKonstantinopoulos, KaliKonstantinopoulos, K.Bhoyar, SoumitraBhoyar, S.Gilkes, D.M.Gilkes, Daniele MMacklin, Paul and Macklin, P.
Cold Spring Harbor Laboratory
 
DAPT: A package enabling distributed automated parameter testing
Gigabyte. | Journal Article
 
Digital twins for predictive oncology will be a paradigm shift for precision cancer care
Hernandez-Boussard, TinaMacklin, PaulGreenspan, Emily JGryshuk, Amy L and Stahlberg, Eric
(pp. 2065-2066). Dec 2021
 
Digital twins for predictive oncology will be a paradigm shift for precision cancer care.
Hernandez Boussard, TinaHernandez-Boussard, TinaMacklin, PaulMacklin, PaulGreenspan, Emily J.Greenspan, Emily JGryshuk, Amy L.Gryshuk, Amy LStahlberg, EricStahlberg, EricSyeda-Mahmood, TanveerSyeda-Mahmood, TanveerShmulevich, Ilya and Shmulevich, Ilya
November 25, 2021
 
Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics.
Wang, JunminDelfarah, AlirezaGelbach, PatrickFong, EmmaMacklin, PaulMumenthaler, Shannon MGraham, Nicholas A and Finley, Stacey
Metabolic engineering, November 25, 2021. | Journal Article
 
Elucidating Tumor-stromal Metabolic Crosstalk in Colorectal Cancer through Integration of Constraint-Based Models and LC-MS Metabolomics
Wang, JunminDelfarah, AlirezaGelbach, PatrickFong, EmmaMacklin, PaulMumenthaler, ShannonGraham, Nicholas Alexander and Finley, Stacey D
Cold Spring Harbor Laboratory
 
Envisioning the future of precision oncology trials
Madhavan, SubhaMadhavan, SubhaBeckman, Robert ABeckman, Robert A.McCoy, Matthew D.McCoy, Matthew DPishvaian, Michael JPishvaian, Michael J.Brody, Jonathan R.Brody, Jonathan RMacklin, Paul and Macklin, Paul
Nature Cancer. | Journal Article
 
High-throughput microscopy reveals the impact of multifactorial environmental perturbations on colorectal cancer cell growth.
Chiang, Chun-TeLau, RoyGhaffarizadeh, AhmadrezaBrovold, MatthewVyas, DipenJuárez, Edwin FAtala, AnthonyAgus, David BSoker, ShayMacklin, PaulRuderman, Daniel and Mumenthaler, Shannon M
GigaScience, vol. 10, (no. 4), April 19, 2021. | Journal Article
 
Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, YafeiBrodin, ErikNishii, KenichiroFrieboes, Hermann B.Mumenthaler, Shannon M.Sparks, Jessica L. and Macklin, Paul
Scientific Reports, vol. 11. | Journal Article
 
Supporting computational apprenticeship through educational and software infrastructure. A case study in a mathematical oncology research lab
Madamanchi, AasakiranThomas, MadisonMagana, AlejandraHeiland, Randy and Macklin, Paul
PRIMUS, pp. 1–42. | Journal Article
2020
Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, YafeiBrodin, ErikNishii, KenichiroFrieboes, Hermann BMumenthaler, ShannonSparks, Jessica L and Macklin, Paul
Cold Spring Harbor Laboratory
 
Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture
Risner, KennethTieu, Katie VWang, YafeiBakovic, AllisonBhalla, NishankNathan, StevenConway, Daniel EMacklin, Paul and Narayanan, Aarthi
Cold Spring Harbor Laboratory
 
Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture.
Risner, Kenneth HTieu, Katie VWang, YafeiBakovic, AllisonAlem, FarhangBhalla, NishankNathan, StevenConway, Daniel EMacklin, Paul and Narayanan, Aarthi
bioRxiv : the preprint server for biology, August 13, 2020. | Journal Article
 
OrgDyn: Feature and model based characterization of spatial and temporal organoid dynamics.
Hasnain, ZakiFraser, Andrew KGeorgess, DanChoi, AlexMacklin, PaulBader, Joel SPeyton, Shelly REwald, Andrew J and Newton, Paul K
Bioinformatics (Oxford, England), February 24, 2020. | Journal Article
 
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View.
Xavier, Joao BXavier, Joao BXavier, J.B.Xavier, Joao BXavier, Joao BXavier, Joao BYoung, Vincent BYoung, V.B.Young, Vincent BYoung, Vincent BYoung, Vincent BYoung, Vincent BSkufca, JosephSkufca, J.Skufca, JosephSkufca, JosephSkufca, JosephSkufca, JosephGinty, FionaGinty, FionaGinty, FionaGinty, FionaGinty, F.Ginty, FionaTesterman, TraciTesterman, TraciTesterman, TraciTesterman, TraciTesterman, TraciTesterman, T.Pearson, Alexander TPearson, Alexander TPearson, Alexander TPearson, A.T.Pearson, Alexander TPearson, Alexander TMacklin, PaulMacklin, PaulMacklin, PaulMacklin, PaulMacklin, P.Macklin, PaulMitchell, A.Mitchell, AmirMitchell, AmirMitchell, AmirMitchell, AmirMitchell, AmirShmulevich, I.Shmulevich, IlyaShmulevich, IlyaShmulevich, IlyaShmulevich, IlyaShmulevich, IlyaXie, LeiXie, LeiXie, LeiXie, LeiXie, LeiXie, L.Caporaso, J GregoryCaporaso, J.G.Caporaso, J GregoryCaporaso, J GregoryCaporaso, J GregoryCaporaso, J GregoryCrandall, K.A.Crandall, Keith ACrandall, Keith ACrandall, Keith ACrandall, Keith ACrandall, Keith ASimone, N.L.Simone, Nicole LSimone, Nicole LSimone, Nicole LSimone, Nicole LSimone, Nicole LGodoy-Vitorino, FilipaGodoy-Vitorino, FilipaGodoy-Vitorino, FilipaGodoy-Vitorino, FilipaGodoy-Vitorino, FilipaGodoy-Vitorino, F.Griffin, Timothy JGriffin, Timothy JGriffin, T.J.Griffin, Timothy JGriffin, Timothy JGriffin, Timothy JWhiteson, Katrine LWhiteson, Katrine LWhiteson, Katrine LWhiteson, Katrine LWhiteson, K.L.Whiteson, Katrine LGustafson, Heather HGustafson, H.H.Gustafson, Heather HGustafson, Heather HGustafson, Heather HGustafson, Heather HSlade, Daniel JSlade, Daniel JSlade, Daniel JSlade, Daniel JSlade, D.J.Slade, Daniel JSchmidt, Thomas MSchmidt, Thomas MSchmidt, Thomas MSchmidt, Thomas MSchmidt, T.M.Schmidt, Thomas MWalther-Antonio, M.R.S.Walther-Antonio, Marina R SWalther-Antonio, Marina R SWalther-Antonio, Marina R SWalther-Antonio, Marina R SWalther-Antonio, Marina R SKorem, T.Korem, TalKorem, TalKorem, TalKorem, TalKorem, TalWebb-Robertson, Bobbie-Jo MWebb-Robertson, B.-J.M.Webb-Robertson, Bobbie-Jo MWebb-Robertson, Bobbie-Jo MWebb-Robertson, Bobbie-Jo MWebb-Robertson, Bobbie-Jo MStyczynski, Mark PStyczynski, Mark PStyczynski, M.P.Styczynski, Mark PStyczynski, Mark PStyczynski, Mark PJohnson, W EvanJohnson, W EvanJohnson, W.E.Johnson, W EvanJohnson, W EvanJohnson, W EvanJobin, ChristianJobin, ChristianJobin, ChristianJobin, ChristianJobin, C.Jobin, ChristianRidlon, Jason MRidlon, J.M.Ridlon, Jason MRidlon, Jason MRidlon, Jason MRidlon, Jason MKoh, Andrew YKoh, Andrew YKoh, Andrew YKoh, Andrew YKoh, Andrew YKoh, A.Y.Yu, M.Yu, MichaelYu, MichaelYu, MichaelYu, MichaelYu, MichaelKelly, L.Kelly, LibushaKelly, LibushaKelly, LibushaKelly, LibushaKelly, LibushaWargo, Jennifer AWargo, Jennifer AWargo, Jennifer AWargo, Jennifer AWargo, J.A. and Wargo, Jennifer A
Trends in cancer, vol. 6, (no. 3), pp. 192-204, March 2020. | Journal Article
2019
A Review of Cell-Based Computational Modeling in Cancer Biology
Metzcar, JohnWang, YafeiHeiland, Randy and Macklin, Paul
JCO Clinical Cancer Informatics. | Journal Article