14 Publications
2013
Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.
Hu, Peng⋅Herrmann, Rolf⋅Bednar, Amanda⋅Saloupis, Peter⋅Dwyer, Mary A⋅Yang, Ping⋅Qi, Xiaoping⋅Thomas, Russell S⋅Jaffe, Glenn J⋅Boulton, Michael E⋅Mc Donnell, Donald P and Malek, Goldis
Proceedings of the National Academy of Sciences of the United States of America, vol. 110, (no. 43), pp. E4069-78, 2013/Oct/22. | Journal Article
 
Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.
Yan, Yuanqing⋅Salazar, Tatiana E⋅Dominguez, James M⋅Nguyen, Dung V⋅Li Calzi, Sergio⋅Bhatwadekar, Ashay⋅Qi, Xiaoping⋅Busik, Julia V⋅Boulton, Mike E and Grant, Maria B
PloS one, vol. 8, (no. 11), pp. e80029, 2013. | Journal Article
 
Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction.
Hu, Yang⋅Chen, Ying⋅Ding, Lexi⋅He, Xuemin⋅Takahashi, Yusuke⋅Gao, Yang⋅Shen, Wei⋅Cheng, Rui⋅Chen, Qian⋅Qi, Xiaoping⋅Boulton, Mike E and Ma, Jian Xing
Proceedings of the National Academy of Sciences of the United States of America, vol. 110, (no. 38), pp. 15401-6, 2013/Sep/17. | Journal Article
 
Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.
Bhatwadekar, Ashay⋅Yan, Yuanqing⋅Qi, Xiaoping⋅Thinschmidt, Jeffrey S⋅Neu, Matthew B⋅Li Calzi, Sergio⋅Shaw, Lynn⋅Dominiguez, James M⋅Busik, Julia V⋅Lee, Choogon⋅Boulton, Mike E and Grant, Maria B
Diabetes, vol. 62, (no. 1), pp. 273-82, 2013/Jan. | Journal Article
 
Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.
Liu, Li⋅Qi, Xiaoping⋅Chen, Zhijuan⋅Shaw, Lynn⋅Cai, Jun⋅Smith, Layton H⋅Grant, Maria B and Boulton, Mike E
The American journal of pathology, vol. 182, (no. 4), pp. 1412-24, 2013/Apr. | Journal Article
2012
Autophagy in the retina: a potential role in age-related macular degeneration.
Mitter, Sayak K⋅Rao, Haripriya V⋅Qi, Xiaoping⋅Cai, Jun⋅Sugrue, Andrew⋅Dunn, William A⋅Grant, Maria B and Boulton, Mike E
Advances in experimental medicine and biology, vol. 723, pp. 83-90, 2012. | Journal Article
 
The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.
Thampi, Prajitha⋅Rao, Haripriya V⋅Mitter, Sayak K⋅Cai, Jun⋅Mao, Haoyu⋅Li, Hong⋅Seo, Soojung⋅Qi, Xiaoping⋅Lewin, Alfred S⋅Romano, Carl and Boulton, Mike E
PloS one, vol. 7, (no. 4), pp. e34468, 2012. | Journal Article
 
γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.
Qi, Xiaoping⋅Cai, Jun⋅Ruan, Qing⋅Liu, Li⋅Boye, Sanford L⋅Chen, Zhijuan⋅Hauswirth, William W⋅Ryals, Renee C⋅Shaw, Lynn C⋅Caballero, Sergio⋅Grant, Maria B and Boulton, Mike E
Investigative ophthalmology & visual science, vol. 53, (no. 2), pp. 574-85, 2012/Feb. | Journal Article
2011
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).
Kielczewski, Jennifer L⋅Li Calzi, Sergio⋅Shaw, Lynn⋅Cai, Jun⋅Qi, Xiaoping⋅Ruan, Qing⋅Wu, Lin⋅Liu, Li⋅Hu, Ping⋅Chan Ling, Tailoi⋅Mames, Robert N⋅Firth, Sue⋅Baxter, Robert C⋅Turowski, Patric⋅Busik, Julia V⋅Boulton, Mike E and Grant, Maria B
Investigative ophthalmology & visual science, vol. 52, (no. 11), pp. 8278-86, 2011. | Journal Article
 
PEDF regulates vascular permeability by a γ-secretase-mediated pathway.
Cai, Jun⋅Wu, Lin⋅Qi, Xiaoping⋅Li Calzi, Sergio⋅Caballero, Sergio⋅Shaw, Lynn⋅Ruan, Qing⋅Grant, Maria B and Boulton, Mike E
PloS one, vol. 6, (no. 6), pp. e21164, 2011. | Journal Article
 
Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability.
Cai, Jun⋅Wu, Lin⋅Qi, Xiaoping⋅Shaw, Lynn C⋅Li Calzi, Sergio⋅Caballero, Sergio⋅Jiang, W. G⋅Vinores, Stanley A⋅Antonetti, David A⋅Ahmed, Asif⋅Grant, Maria B and Boulton, Mike E
PloS one, vol. 6, (no. 3), pp. e18076, 2011. | Journal Article
 
γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.
Cai, Jun⋅Chen, Zhijuan⋅Ruan, Qing⋅Han, Song⋅Liu, Li⋅Qi, Xiaoping⋅Boye, Sanford L⋅Hauswirth, William W⋅Grant, Maria B and Boulton, Mike E
The Journal of biological chemistry, vol. 286, (no. 49), pp. 42514-23, 2011/Dec/9. | Journal Article
2007
Dual gene therapy with extracellular superoxide dismutase and catalase attenuates experimental optic neuritis
Qi, Xiaoping⋅Hauswirth, William W and Guy, John
Molecular Vision, vol. 13, pp. 1-11, 2007. | Journal Article
2003
Optic neuropathy induced by reductions in mitochondrial superoxide dismutase.
Qi, Xiaoping⋅Lewin, Alfred S⋅Hauswirth, William W and Guy, John
Investigative ophthalmology & visual science, vol. 44, (no. 3), pp. 1088-96, 2003/Mar. | Journal Article