61 Publications (Page 2 of 3)
2015
Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg
Biswas, Moanaro⋅Biswas, Moanaro⋅Biswas, Moanaro⋅Biswas, Moanaro⋅Sarkar, Debalina⋅Sarkar, Debalina⋅Sarkar, Debalina⋅Sarkar, Debalina⋅Kumar, Sandeep R P⋅Kumar, Sandeep R P⋅Kumar, Sandeep R P⋅Kumar, Sandeep R P⋅Nayak, Sushrusha⋅Nayak, Sushrusha⋅Nayak, Sushrusha⋅Nayak, Sushrusha⋅Rogers, Geoffrey L⋅Rogers, Geoffrey L⋅Rogers, Geoffrey L⋅Rogers, Geoffrey L⋅Markusic, David M⋅Markusic, David M⋅Markusic, David M⋅Markusic, David M⋅Liao, Gongxian⋅Liao, Gongxian⋅Liao, Gongxian⋅Liao, Gongxian⋅Terhorst, Cox⋅Terhorst, Cox⋅Terhorst, Cox⋅Terhorst, Cox⋅Herzog, Roland W⋅Herzog, Roland W⋅Herzog, Roland W and Herzog, Roland W
Blood, vol. 125, (no. 19), pp. 2947, 2015-May-07. | Journal Article
 
Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer
Rogers, Geoffrey L⋅Rogers, Geoffrey L⋅Suzuki, Masataka⋅Suzuki, Masataka⋅Zolotukhin, Irene⋅Zolotukhin, Irene⋅Markusic, David M⋅Markusic, David M⋅Morel, Laurence M⋅Morel, Laurence M⋅Lee, Brendan⋅Lee, Brendan⋅Ertl, Hildegund C.J⋅Ertl, Hildegund C J⋅Herzog, Roland W and Herzog, Roland W
Journal of Innate Immunity, vol. 7, (no. 3), pp. 314, 20150400. | Journal Article
2014
A David promoter with Goliath strength
Markusic, D.M. and Herzog, R.W.
Blood, vol. 123, pp. 3068-3069. | Journal Article
 
Development of gene transfer for induction of antigen-specific tolerance
Sack, Brandon K⋅Sack, Brandon K⋅Herzog, Roland W⋅Herzog, Roland W⋅Terhorst, Cox⋅Terhorst, Cox⋅Markusic, David M and Markusic, David M
Molecular therapy. Methods & clinical development, vol. 1, (no. C), pp. 14013, 2014-Apr-30. | Journal Article
 
Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia
Sarkar, Debalina⋅Sarkar, Debalina⋅Sarkar, D.⋅Sarkar, Debalina⋅Biswas, Moanaro⋅Biswas, M.⋅Biswas, Moanaro⋅Biswas, Moanaro⋅Liao, Gongxian⋅Liao, G.⋅Liao, Gongxian⋅Liao, Gongxian⋅Seay, Howard R⋅Seay, Howard R⋅Seay, Howard R⋅Seay, H.R.⋅Perrin, G.Q.⋅Perrin, George Q⋅Perrin, George Q⋅Perrin, George Q⋅Markusic, David M⋅Markusic, David M⋅Markusic, D.M.⋅Markusic, David M⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Hoffman, B.E.⋅Brusko, T.M.⋅Brusko, Todd M⋅Brusko, Todd M⋅Brusko, Todd M⋅Terhorst, Cox⋅Terhorst, Cox⋅Terhorst, C.⋅Terhorst, Cox⋅Herzog, Roland W⋅Herzog, R.W.⋅Herzog, Roland W and Herzog, Roland W
Molecular therapy. Methods & clinical development, vol. 1, (no. C), pp. 14030, 2014-Jul-30. | Journal Article
 
Immune Response to FIX Is Dependent on Mouse Background Strain and Modulated By TLR4
Markusic, David M
Blood, vol. 124, (no. 21), pp. 1479, 2014-12-06. | Journal Article
 
Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants
Marsic, Damien⋅Marsic, Damien⋅Marsic, Damien⋅Govindasamy, Lakshmanan⋅Govindasamy, Lakshmanan⋅Govindasamy, Lakshmanan⋅Currlin, Seth⋅Currlin, Seth⋅Currlin, Seth⋅Markusic, David M⋅Markusic, David M⋅Markusic, David M⋅Tseng, Yu-shan⋅Tseng, Yu-Shan⋅Tseng, Yu-Shan⋅Herzog, Roland W⋅Herzog, Roland W⋅Herzog, Roland W⋅Agbandje-mckenna, Mavis⋅Agbandje-McKenna, Mavis⋅Agbandje-McKenna, Mavis⋅Zolotukhin, Sergei⋅Zolotukhin, Sergei and Zolotukhin, Sergei
Molecular Therapy, vol. 22, (no. 11), pp. 1909, November 2014. | Journal Article
2013
Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
Markusic, David⋅Markusic, David M⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Perrin, George Q⋅Perrin, George Q⋅Nayak, Sushrusha⋅Nayak, Sushrusha⋅Wang, Xiaomei⋅Wang, Xiaomei⋅Loduca, Paul A⋅LoDuca, Paul A⋅High, Katherine A⋅High, Katherine A⋅Herzog, Roland W and Herzog, Roland W
EMBO Molecular Medicine, vol. 5, (no. 11), pp. 1709, November 2013. | Journal Article
 
Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells
Martino, Ashley T⋅Martino, Ashley T⋅Basner-Tschakarjan, Etiena⋅Basner-Tschakarjan, Etiena⋅Markusic, David M⋅Markusic, David⋅Finn, Jonathan D⋅Finn, Jonathan D⋅Hinderer, Christian⋅Hinderer, Christian⋅Zhou, Shangzhen⋅Zhou, Shangzhen⋅Ostrov, David A⋅Ostrov, David A⋅Srivastava, Arun⋅Srivastava, Arun⋅Ertl, Hildegund C⋅Ertl, Hildegund C J⋅Terhorst, Cox⋅Terhorst, Cox⋅High, Katherine A⋅High, Katherine A⋅Mingozzi, Federico⋅Mingozzi, Federico⋅Herzog, Roland W and Herzog, Roland W
Blood, vol. 121, (no. 12), pp. 2233, 2013-Mar-21. | Journal Article
 
-Book chapter-
Sack, B.K.⋅Markusic, D.M. and Herzog, R.W.
In Induction of immunological tolerance to transgene products. (pp. 297-311). 2013
 
Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia
Markusic, David and Herzog, Roland
Journal of Genetic Syndromes & Gene Therapy, pp. 1, 20130101. | Journal Article
2012
In Vivo Model to Evaluate Loss of Liver-Derived Factor IX Expression Caused by AAV Capsid-Specific CD8+ T Cells
Markusic, David M⋅Martino, Ashley T⋅Mingozzi, Federico⋅High, Katherine A and Herzog, Roland W
Blood, vol. 120, (no. 21), pp. 2046, 2012-11-16. | Journal Article
 
Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia
Markusic, David M⋅Markusic, David M⋅Herzog, Roland W and Herzog, Roland W
Journal of genetic syndromes & gene therapy, vol. 1, (no. 2), pp. 9, 2012-Jan-18. | Journal Article
 
Suppression of Inhibitor Formation in Protein and Gene Therapy for Hemophilia Using Ex Vivo Expanded Treg
Sarkar, Debalina⋅Markusic, David M⋅Terhorst, Cox⋅Brusko, Todd and Herzog, Roland W
Blood, vol. 120, (no. 21), pp. 13, 2012-11-16. | Journal Article
 
Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy
Sack, Brandon K⋅Sack, Brandon K⋅Sack, B. K.⋅Merchant, S.⋅Merchant, Sherin⋅Merchant, Sherin⋅Markusic, David M⋅Markusic, David⋅Markusic, D. M.⋅Nathwani, A. C.⋅Nathwani, Amit C⋅Nathwani, Amit C⋅Davidoff, A. M.⋅Davidoff, Andrew M⋅Davidoff, Andrew M⋅Byrne, Barry J⋅Byrne, Barry J⋅Byrne, B. J.⋅Herzog, R. W.⋅Herzog, Roland W and Herzog, Roland W
PloS one, vol. 7, (no. 5), pp. e37671, 2012-00-00. | Journal Article
2011
AAV Vector Biology in Primates: Finding the Missing Link?
Herzog, Roland W⋅Herzog, Roland W⋅Davidoff, Andrew M⋅Davidoff, Andrew M⋅Markusic, David M⋅Markusic, David⋅Nathwani, Amit C and Nathwani, Amit C
Molecular Therapy, vol. 19, (no. 11), pp. 1924, November 2011. | Journal Article
 
Hepatic Gene Transfer of Factor IX Reverses Inhibitors and Protects From Anaphylaxis in a Murine Hemophilia B Model
Markusic, David and Herzog, Roland W
Blood, vol. 118, (no. 21), pp. 669, 2011-11-18. | Journal Article
 
The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver
Martino, Ashley T⋅Martino, Ashley T⋅Suzuki, Masataka⋅Suzuki, Masataka⋅Markusic, David⋅Markusic, David M⋅Zolotukhin, Irene⋅Zolotukhin, Irene⋅Ryals, Renee C⋅Ryals, Renee C⋅Moghimi, Babak⋅Moghimi, Babak⋅Ertl, Hildegund C⋅Ertl, Hildegund C J⋅Muruve, Daniel A⋅Muruve, Daniel A⋅Lee, Brendan⋅Lee, Brendan⋅Herzog, Roland W and Herzog, Roland W
Blood, vol. 117, (no. 24), pp. 6468, 2011-Jun-16. | Journal Article
 
Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin
Moghimi, B⋅Moghimi, Babak⋅Sack, Brandon K⋅Sack, B K⋅Nayak, Sushrusha⋅Nayak, S⋅Markusic, David⋅Markusic, David M⋅Mah, Cathryn S⋅Mah, Cathryn⋅Herzog, Roland W and Herzog, Roland W
Journal of thrombosis and haemostasis : JTH, vol. 9, (no. 8), pp. 1533, 2011-08-01. | Journal Article
2010
Doxycycline regulated lentiviral vectors.
Markusic, David⋅Markusic, D.⋅Seppen, Jurgen and Seppen, J.
Methods in molecular biology (Clifton, N.J.), vol. 614, pp. 69-76. | Journal Article
 
High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines
Markusic, David⋅Markusic, David M⋅Markusic, David M⋅Herzog, Roland W⋅Herzog, Roland W⋅Herzog, Roland W⋅Aslanidi, George V⋅Aslanidi, George V⋅Aslanidi, George V⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Li, Baozheng⋅Li, Baozheng⋅Li, Baozheng⋅Li, Mengxin⋅Li, Mengxin⋅Li, Mengxin⋅Jayandharan, Giridhara R⋅Jayandharan, Giridhara R⋅Jayandharan, Giridhara R⋅Ling, Chen⋅Ling, Chen⋅Ling, Chen⋅Zolotukhin, Irene⋅Zolotukhin, Irene⋅Zolotukhin, Irene⋅Ma, Wenqin⋅Ma, Wenqin⋅Ma, Wenqin⋅Zolotukhin, Sergei⋅Zolotukhin, Sergei⋅Zolotukhin, Sergei⋅Srivastava, Arun⋅Srivastava, Arun⋅Srivastava, Arun⋅Zhong, Li⋅Zhong, Li and Zhong, Li
Molecular Therapy, vol. 18, (no. 12), pp. 2056, December 2010. | Journal Article
 
Humoral and Anaphylactic Responses to Factor IX In Murine Hemophilia B Are Genotype Dependent and Can Be Reversed by Hepatic Gene Transfer
Markusic, David⋅Nayak, Sushrusha and Herzog, Roland W
Blood, vol. 116, (no. 21), pp. 2202, 2010-11-19. | Journal Article
 
Self-Complementary AAV Vectors Cause a Substantially Heightened TLR9-Dependent Innate Immune Response In the Liver
Martino, Ashley T⋅Suzuki, Masataka⋅Markusic, David⋅Zolotukhin, Irene⋅Muruve, Daniel A⋅Lee, Brendan and Herzog, Roland W
Blood, vol. 116, (no. 21), pp. 252, 2010-11-19. | Journal Article
 
Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats
Markusic, David⋅Markusic, David⋅de Waart, Dirk R⋅Waart, Dirk⋅Seppen, Jurgen and Seppen, Jurgen
PLoS ONE, vol. 5, (no. 4), pp. e9974, 2010. | Journal Article
 
Synthetic gene regulation circuits for control of cell expansion
May, T.⋅May, Tobias⋅Butueva, M.⋅Butueva, Milada⋅Bantner, S.⋅Bantner, Sara⋅Markusic, D.⋅Markusic, David⋅Seppen, J.⋅Seppen, Jurgen⋅MacLeod, Roderick A⋅MacLeod, R.A.F.⋅Weich, Herbert⋅Weich, H.⋅Hauser, H.⋅Hauser, Hansjörg⋅Wirth, Dagmar and Wirth, D.
Tissue Engineering - Part A, vol. 16, pp. 441-452. | Journal Article