44 Publications (Page 1 of 2)
2018
De novo unbalanced translocations have a complex history/aetiology
Bonaglia, MariaKurtas, NehirErrichiello, EdoardoBertuzzo, SaraBeri, SilvanaMehrjouy, ManaProvenzano, AldesiaVergani, DeboraPecile, VannaNovara, FrancescaReho, PaoloDi Giacomo, MarilenaDiscepoli, GiancarloGiorda, RobertoAldred, MichealaSantos-Rebouças, CíntiaGoncalves, AndressaAbuelo, DianeGiglio, SabrinaRicca, IvanaFranchi, FabriziaPatsalis, PhilipposSismani, CarolinaMorí, MaríaNevado, JuliánTommerup, Niels and Zuffardi, Orsetta
Human Genetics, vol. 137, (no. 10), pp. 829, 20181000. | Journal Article
 
Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis
Planchon, Sarah MLingas, Karen TReese Koç, JaneHooper, Brittney MMaitra, BasabiFox, Robert MImrey, Peter BDrake, Kylie MAldred, Micheala ALazarus, Hillard M and Cohen, Jeffrey A
Multiple Sclerosis Journal – Experimental, Translational and Clinical, vol. 4, (no. 1), pp. 2055217318765288, 20180300. | Journal Article
 
Genetics and genomics of pulmonary arterial hypertension
Morrell, Nicholas WMorrell, Nicholas WMorrell, Nicholas WAldred, Micheala AAldred, Micheala AAldred, Micheala AChung, Wendy KChung, Wendy KChung, Wendy KElliott, C GregoryElliott, C GregoryElliott, C GregoryNichols, William CNichols, William CNichols, William CSoubrier, FlorentSoubrier, FlorentSoubrier, FlorentTrembath, Richard CTrembath, Richard CTrembath, Richard CLoyd, James ELoyd, James E and Loyd, James E
The European respiratory journal, vol. 53, (no. 1), pp. 1801899, 2018-Dec-13. | Journal Article
 
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
Graf, StefanGräf, StefanHaimel, MatthiasHaimel, MatthiasBleda, MartaBleda, MartaHadinnapola, CharakaHadinnapola, CharakaSouthgate, LauraSouthgate, LauraLi, WeiLi, WeiHodgson, JoshuaHodgson, JoshuaLiu, BinLiu, BinSalmon, RichardSalmon, RichardSouthwood, MarkSouthwood, MarkMachado, RajivMachado, RajivMartin, JenniferMartin, JenniferTreacy, CarmenTreacy, CarmenYates, KatherineYates, KatherineDaugherty, LouiseDaugherty, LouiseShamardina, OlgaShamardina, OlgaWhitehorn, DeborahWhitehorn, DeborahHolden, SimonHolden, SimonAldred, MichealaAldred, MichealaBogaard, HarmBogaard, HarmChurch, ColinChurch, ColinCoghlan, GerryCoghlan, GerryCondliffe, RobinCondliffe, RobinCorris, PaulCorris, PaulDanesino, CesareDanesino, CesareEyries, MelanieEyries, MélanieGall, HenningGall, HenningGhio, StefanoGhio, StefanoGhofrani, Hossein-ArdeschirGhofrani, Hossein-ArdeschirGibbs, J.Gibbs, JGirerd, BarbaraGirerd, BarbaraHouweling, ArjanHouweling, ArjanHoward, LukeHoward, LukeHumbert, MarcHumbert, MarcKiely, DavidKiely, DavidKovacs, GaborKovacs, GaborMacKenzie Ross, RobertRoss, RobertMoledina, ShahinMoledina, ShahinMontani, DavidMontani, DavidNewnham, MichaelNewnham, MichaelOlschewski, AndreaOlschewski, AndreaOlschewski, HorstOlschewski, HorstPeacock, AndrewPeacock, AndrewPepke-Zaba, JoannaPepke-Zaba, JoannaProkopenko, IngaProkopenko, IngaRhodes, ChristopherRhodes, ChristopherScelsi, LauraScelsi, LauraSeeger, WernerSeeger, WernerSoubrier, FlorentSoubrier, FlorentStein, DanStein, DanSuntharalingam, JaySuntharalingam, JaySwietlik, EmiliaSwietlik, EmiliaToshner, MarkToshner, MarkHeel, DavidHeel, DavidVonk Noordegraaf, AntonNoordegraaf, AntonWaisfisz, QuintenWaisfisz, QuintenWharton, JohnWharton, JohnWort, StephenWort, StephenOuwehand, WillemOuwehand, WillemSoranzo, NicoleSoranzo, NicoleLawrie, AllanLawrie, AllanUpton, PaulUpton, PaulWilkins, MartinWilkins, MartinTrembath, RichardTrembath, RichardMorrell, Nicholas and Morrell, Nicholas
2018. | Journal Article
 
LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections
Guo, Dong-chuanRegalado, Ellen SPinard, AmelieChen, JiyuanLee, KwanghyukRigelsky, ChristinaZilberberg, LiorHostetler, Ellen MAldred, MichealaWallace, Stephanie EPrakash, Siddharth KLeal, Suzanne MBamshad, Michael JNickerson, Deborah ANatowicz, MarvinRifkin, Daniel B and Milewicz, Dianna M
The American Journal of Human Genetics, vol. 102, (no. 4), pp. 712, 2018-04-05. | Journal Article
2017
Genomic stability of pulmonary artery endothelial colony-forming cells in culture
Drake, Kylie MFederici, ChiaraDuong, Heng TComhair, Suzy AErzurum, Serpil CAsosingh, Kewal and Aldred, Micheala A
Pulmonary Circulation, vol. 7, (no. 2), pp. 427, 20170300. | Journal Article
 
PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics
Hemnes, A.R.Hemnes, Anna RBeck, G.J.Beck, Gerald JNewman, John HNewman, J.H.Abidov, A.Abidov, AidenAldred, M.A.Aldred, Micheala ABarnard, JohnBarnard, J.Rosenzweig, E.B.Berman Rosenzweig, ErikaBorlaug, Barry ABorlaug, B.A.Chung, Wendy KChung, W.K.Comhair, S.A.A.Comhair, Suzy A AErzurum, Serpil CErzurum, S.C.Frantz, R.P.Frantz, Robert PGray, M.P.Gray, Michael PGrunig, GabrieleGrunig, G.Hassoun, P.M.Hassoun, Paul MHill, Nicholas SHill, N.S.Horn, E.M.Horn, Evelyn MHu, B.Hu, BoLempel, J.K.Lempel, Jason KMaron, Bradley AMaron, B.A.Mathai, Stephen CMathai, S.C.Olman, M.A.Olman, Mitchell ARischard, Franz PRischard, F.P.Systrom, David MSystrom, D.M.Tang, W.H.W.Tang, W H WilsonWaxman, Aaron BWaxman, A.B.Xiao, L.Xiao, LeiYuan, Jason X-JYuan, J.X.-J.Leopold, Jane A and Leopold, J.A.
Circulation research, vol. 121, (no. 10), pp. 1139, 2017-10-27. | Journal Article
2016
Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension
Farha, SamarFarha, SamarHu, BoHu, BoComhair, SuzyComhair, SuzyZein, JoeZein, JoeDweik, RaedDweik, RaedErzurum, Serpil CErzurum, Serpil CAldred, Micheala A and Aldred, Micheala A
PloS one, vol. 11, (no. 5), pp. e0156042, 2016-00-00. | Journal Article
2015
Endothelial chromosome 13 deletion in congenital heart disease-associated pulmonary arterial hypertension dysregulates SMAD9 signaling
Drake, Kylie MDrake, KylieComhair, Suzy AComhair, SuzyErzurum, Serpil CErzurum, SerpilTuder, RubinTuder, Rubin MAldred, Micheala A and Aldred, Micheala
American journal of respiratory and critical care medicine, vol. 191, (no. 7), pp. 854, 2015-Apr-01. | Journal Article
 
Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension
Federici, ChiaraFederici, ChiaraDrake, Kylie MDrake, Kylie MRigelsky, Christina MRigelsky, Christina MMcNelly, Lauren NMcNelly, Lauren NMeade, Sirena LMeade, Sirena LComhair, Suzy A AComhair, Suzy A AErzurum, Serpil CErzurum, Serpil CAldred, Micheala A and Aldred, Micheala A
American journal of respiratory and critical care medicine, vol. 192, (no. 2), pp. 228, 2015-Jul-15. | Journal Article
 
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects
Machado, Rajiv DMachado, Rajiv DMachado, Rajiv DMachado, Rajiv DSouthgate, LauraSouthgate, LauraSouthgate, LauraSouthgate, LauraEichstaedt, Christina AEichstaedt, Christina AEichstaedt, Christina AEichstaedt, Christina AAldred, Micheala AAldred, Micheala AAldred, Micheala AAldred, Micheala AAustin, Eric DAustin, Eric DAustin, Eric DAustin, Eric DBest, D HunterBest, D. HunterBest, D. HunterBest, D. HunterChung, Wendy KChung, Wendy KChung, Wendy KChung, Wendy KBenjamin, NicolaBenjamin, NicolaBenjamin, NicolaBenjamin, NicolaElliott, C. GregoryElliott, C GregoryElliott, C. GregoryElliott, C. GregoryEyries, MélanieEyries, MélanieEyries, MélanieEyries, MélanieFischer, ChristineFischer, ChristineFischer, ChristineFischer, ChristineGräf, StefanGräf, StefanGräf, StefanGräf, StefanHinderhofer, KatrinHinderhofer, KatrinHinderhofer, KatrinHinderhofer, KatrinHumbert, MarcHumbert, MarcHumbert, MarcHumbert, MarcKeiles, Steven BKeiles, Steven BKeiles, Steven BKeiles, Steven BLoyd, James ELoyd, James ELoyd, James ELoyd, James EMorrell, Nicholas WMorrell, Nicholas WMorrell, Nicholas WMorrell, Nicholas WNewman, John HNewman, John HNewman, John HNewman, John HSoubrier, FlorentSoubrier, FlorentSoubrier, FlorentSoubrier, FlorentTrembath, Richard CTrembath, Richard CTrembath, Richard CTrembath, Richard CViales, Rebecca RodríguezViales, Rebecca RodríguezViales, Rebecca RodríguezViales, Rebecca RodríguezGrünig, EkkehardGrünig, EkkehardGrünig, Ekkehard and Grünig, Ekkehard
Human Mutation, vol. 36, (no. 12), pp. 1127, December 2015. | Journal Article
 
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
Long, LuLong, LuLong, LuOrmiston, Mark LOrmiston, Mark LOrmiston, Mark LYang, XudongYang, XudongYang, XudongSouthwood, MarkSouthwood, MarkSouthwood, MarkGräf, StefanGräf, StefanGräf, StefanMachado, Rajiv DMachado, Rajiv DMachado, Rajiv DMueller, MatthiasMueller, MatthiasMueller, MatthiasKinzel, BerndKinzel, BerndKinzel, BerndYung, Lai MingYung, Lai MingYung, Lai MWilkinson, Janine MWilkinson, Janine MWilkinson, Janine MMoore, Stephen DMoore, Stephen DMoore, Stephen DDrake, Kylie MDrake, Kylie MDrake, Kylie MAldred, Micheala AAldred, Micheala AAldred, Micheala AYu, Paul BYu, Paul BYu, Paul BUpton, Paul DUpton, Paul DUpton, Paul DMorrell, Nicholas WMorrell, Nicholas W and Morrell, Nicholas W
Nature medicine, vol. 21, (no. 7), pp. 785, 2015-Jul. | Journal Article
2014
Genetics and genomics of pulmonary arterial hypertension
Soubrier, FlorentSoubrier, FlorentChung, Wendy KChung, Wendy KMachado, RajivMachado, RajivGrünig, EkkehardGrünig, EkkehardAldred, MichealaAldred, MichealaGeraci, MarkGeraci, MarkLoyd, James ELoyd, James EElliott, C GregoryElliott, C GregoryTrembath, Richard CTrembath, Richard CNewman, John HNewman, John HHumbert, Marc and Humbert, Marc
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, vol. 42 Suppl 1, pp. 17, 2014-Oct. | Journal Article
2013
Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension
Drake, Kylie MDrake, Kylie MDunmore, Benjamin JDunmore, Benjamin JMcNelly, Lauren NMcNelly, Lauren NMorrell, NicholasMorrell, Nicholas WAldred, Micheala A and Aldred, Micheala
American journal of respiratory cell and molecular biology, vol. 49, (no. 3), pp. 409, 2013-Sep. | Journal Article
 
Genetics and genomics of pulmonary arterial hypertension
Soubrier, FlorentSoubrier, FlorentSoubrier, FlorentChung, Wendy KChung, Wendy KChung, Wendy KMachado, RajivMachado, RajivMachado, RajivGrünig, EkkehardGrünig, EkkehardGrünig, EkkehardAldred, MichealaAldred, MichealaAldred, MichealaGeraci, MarkGeraci, Mark WGeraci, MarkLoyd, James ELoyd, James ELoyd, James EElliott, C GElliott, C GregoryElliott, C GregoryTrembath, Richard CTrembath, Richard CTrembath, R CNewman, John HNewman, John HNewman, John HHumbert, MarcHumbert, Marc and Humbert, Marc
Journal of the American College of Cardiology, vol. 62, (no. 25 Suppl), pp. D13, 2013-Dec-24. | Journal Article
 
The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations
Dunmore, Benjamin JDunmore, Benjamin JDrake, Kylie MDrake, Kylie MUpton, Paul DUpton, Paul DToshner, Mark RToshner, Mark RAldred, MichealaAldred, Micheala AMorrell, Nicholas and Morrell, Nicholas W
Human molecular genetics, vol. 22, (no. 18), pp. 3679, 2013-Sep-15. | Journal Article
2012
Human primary lung endothelial cells in culture.
Comhair, Suzy AComhair, Suzy A AXu, WeilingXu, WeilingMavrakis, LoriMavrakis, LoriAldred, Micheala AAldred, MichealaAsosingh, KewalAsosingh, KewalErzurum, Serpil C and Erzurum, Serpil C
American journal of respiratory cell and molecular biology, vol. 46, (no. 6), pp. 723-30, 2012/Jun. | Journal Article
 
Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension
Asosingh, KewalAsosingh, KewalFarha, SamarFarha, SamarLichtin, AlanLichtin, AlanGraham, BrianGraham, BrianGeorge, DeepaGeorge, DeepaAldred, MichealaAldred, MichealaHazen, Stanley LHazen, Stanley LLoyd, JamesLoyd, JamesTuder, RubinTuder, Rubin MErzurum, Serpil C and Erzurum, Serpil C
Blood, vol. 120, (no. 6), pp. 1227, 2012-Aug-09. | Journal Article
2011
Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8
Drake, Kylie MDrake, Kylie MZygmunt, DeborahZygmunt, DeborahMavrakis, LoriMavrakis, LoriHarbor, PhyllisHarbor, PhyllisWang, LingliWang, LingliComhair, Suzy AComhair, Suzy AErzurum, Serpil CErzurum, Serpil CAldred, Micheala A and Aldred, Micheala
American journal of respiratory and critical care medicine, vol. 184, (no. 12), pp. 1408, 2011-Dec-15. | Journal Article
 
MicroRNA Processing Is Dysregulated by Mutations Associated with Pulmonary Arterial Hypertension.
Drake, Kylie MComhair, Suzy AErzurum, Serpil C and Aldred, Micheala
Proceedings of the American Thoracic Society, vol. 8, (no. 2), pp. 205, 2011/May. | Journal Article
2010
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma
Gibson, JaneThorleifsson, GudmarZhang, MingzhiJonasdottir, AdalbjorgGottfredsdottir, Maria SoffiaHewitt, Alex WMartin, Nicholas GJonasson, FridbertCraig, Jamie EDeWan, AndrewMitchell, PaulWadelius, ClaesPang, Chi PuiLotery, Andrew JChan, Juliana C NMacLeod, AlexKong, AugustineMacgregor, StuartThorsteinsdottir, UnnurMagnusson, Kristinn PMackey, David ALam, Dennis S CSouthgate, LauraTrembath, Richard CJacob, AbyHelgason, AgnarThorleifsson, GudmarThordarson, KristjanSigurdsson, AsgeirStefansson, HreinnAldred, Micheala AGudjonsson, Sigurjon ACree, Angela JWalters, G BragiBurdon, Kathryn PTam, Pancy O SGudmundsdottir, Gudrun JYoung, Terri LStefansson, KariCollier, David AKarwatowski, Wojciech S SSt Clair, DavidMasson, GisliSveinsson, OrnEnnis, SarahHammond, Christopher JHoh, JosephineTang, NelsonWalters, G. BHewitt, AlexanderMasson, GisliHelgason, AgnarDewan, Andrew ThomasDeWan, AndrewSigurdsson, AsgeirJonasdottir, AdalbjorgGudjonsson, Sigurjon AMagnusson, Kristinn PStefansson, HreinnLam, Dennis STam, Pancy OGudmundsdottir, Gudrun JSouthgate, LauraBurdon, KathrynGottfredsdottir, Maria SAldred, MichealaMitchell, PaulSt Clair, DavidCollier, David ATang, NelsonSveinsson, OrnMacgregor, StuartMac Gregor, StuartMartin, Nick GCree, Angela JGibson, JaneMacLeod, AlexMacleod, AlexJacob, AbyEnnis, SarahYoung, Terri LChan, Juliana CKarwatowski, Wojciech SHammond, Christopher JThordarson, KristjanZhang, MingzhiWadelius, ClaesLotery, AndrewTrembath, R CPang, Chi PHoh, JosephineCraig, JamieKong, AugustineMacKey, D.A.Mackey, DavidJonasson, FridbertThorsteinsdottir, Unnur and Stefansson, Kari
Nature Genetics, vol. 42, (no. 10), pp. 906-909, 2010. | Journal Article
 
Somatic Chromosome Abnormalities in the Lungs of Patients with Pulmonary Arterial Hypertension
Aldred, Micheala AAldred, Micheala AAldred, MichealaComhair, Suzy AComhair, Suzy AComhair, Suzy AVarella-Garcia, MarileilaVarella-Garcia, MarileilaVarella-Garcia, MarileilaAsosingh, KewalAsosingh, KewalAsosingh, KewalXu, WeilingXu, WeilingXu, WeilingNoon, George PNoon, George PNoon, George PThistlethwaite, Patricia AThistlethwaite, Patricia AThistlethwaite, Patricia ATuder, Rubin MTuder, Rubin MTuder, Rubin MErzurum, Serpil CErzurum, Serpil CErzurum, Serpil CGeraci, Mark WGeraci, Mark WGeraci, Mark WColdren, Christopher DColdren, Christopher D and Coldren, Christopher D
American journal of respiratory and critical care medicine, vol. 182, (no. 9), pp. 1160, 2010-Nov-01. | Journal Article
 
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
Polgar, PeterErzurum, Serpil CRounds, SharonStevens, TroyAldred, MichealaAliotta, JasonArcher, Stephen LAsosingh, KewalBalaban, RobertBauer, NatalieBhattacharya, JaharBogaard, HarmChoudhary, GauravDorn, Gerald WDweik, Raed AFagan, Karen AFallon, MichaelFinkel, TorenGeraci, Mark WGladwin, Mark THassoun, Paul MHumbert, MarcKaminski, NaftaliKawut, StevenLoscalzo, JosephMc Donald, Donald MMc Murtry, IvanNewman, John HNicolls, Mark RRabinovitch, MarleneShizuru, JudyOka, MasahikoPolgar, PeterRodman, DavidSchumacker, Paul TStenmark, KurtTuder, Rubin MVoelkel, Norbert FSullivan, EugeneWeinshilboum, RichardYoder, Mervin CZhao, YingmingGail, Dorothy and Moore, Timothy M
American journal of respiratory and critical care medicine, vol. 182, (no. 12), pp. 1554-62, 2010/Dec/15. | Journal Article
2008
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension.
Asosingh, KewalAsosingh, KewalAldred, MichealaAldred, MichealaVasanji, AmitVasanji, AmitDrazba, JudithDrazba, JudithSharp, JacquelineSharp, JacquelineFarver, CarolFarver, CarolComhair, SuzyComhair, Suzy AXu, WeilingXu, WeilingLicina, LaurenLicina, LaurenHuang, LanHuang, LanAnand-Apte, BelaAnand-Apte, BelaYoder, Mervin CYoder, MervinTuder, RubinTuder, Rubin MErzurum, Serpil C and Erzurum, Serpil
The American journal of pathology, vol. 172, (no. 3), pp. 615-27, 2008/Mar. | Journal Article
2007
Characterization of the BMPR2 5'-Untranslated Region and a Novel Mutation in Pulmonary Hypertension
Aldred, MichealaAldred, MichealaMachado, RDMachado, RajivJames, V.James, VictoriaMorrell, NicholasMorrell, NicholasTrembath, Richard and Trembath, R C
American Journal of Respiratory and Critical Care Medicine, vol. 176, (no. 8), pp. 819-824, 2007. | Journal Article