91 Publications (Page 2 of 4)
2011
The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1.
Wu, Xiaohua⋅Wu, Xiaohua⋅Wu, Xiaohua⋅Wu, Xiaohua⋅Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅Rhodes, Steven D⋅Rhodes, Steven D⋅Rhodes, Steven D⋅Rhodes, Steven D⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Xiaohong⋅Yang, Xianlin⋅Yang, Xianlin⋅Yang, Xianlin⋅Yang, Xianlin⋅Jiang, Li⋅Jiang, Li⋅Jiang, Li⋅Jiang, Li⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Snider, Paige⋅Snider, Paige⋅Snider, Paige⋅Snider, Paige⋅Robling, Alexander G⋅Robling, Alexander⋅Robling, Alexander G⋅Robling, Alexander G⋅Clapp, D Wade⋅Clapp, D Wade⋅Clapp, D W⋅Clapp, D Wade⋅Conway, Simon J⋅Conway, Simon J⋅Conway, Simon J⋅Conway, Simon J⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun and Yang, Feng Chun
PloS one, vol. 6, (no. 9), pp. e24917, 2011. | Journal Article
2010
Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.
Pulliam-Leath, Anna C⋅Pulliam-Leath, Anna C⋅Pulliam-Leath, Anna C⋅Ciccone, Samantha L⋅Ciccone, Samantha L⋅Ciccone, Samantha L⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Li, Xiaxin⋅Li, Xiaxin⋅Li, Xiaxin⋅Si, Yue⋅Si, Yue⋅Si, Yue⋅Miravalle, Leticia⋅Miravalle, Leticia⋅Miravalle, Leticia⋅Smith, Danielle⋅Smith, Danielle⋅Smith, Danielle⋅Yuan, Jin⋅Yuan, Jin⋅Yuan, Jin⋅Li, Jingling⋅Li, Jingling⋅Li, Jingling⋅Anur, Praveen⋅Anur, Praveen⋅Anur, Praveen⋅Orazi, Attilio⋅Orazi, Attilio⋅Orazi, Attilio⋅Vance, Gail H⋅Vance, Gail H⋅Vance, Gail H⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Yang, Feng-Chun⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Bagby, Grover C⋅Bagby, Grover C⋅Bagby, Grover C⋅Clapp, D Wade⋅Clapp, D Wade and Clapp, D W
Blood, vol. 116, (no. 16), pp. 2915-20, 2010/Oct/21. | Journal Article
 
Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors.
Benson, Eric A⋅Benson, Eric⋅Goebl, Mark⋅Goebl, Mark G⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Kapur, Reuben⋅Kapur, Reuben⋅McClintick, Jeanette⋅McClintick, Jeanette⋅Sanghani, Sonal⋅Sanghani, Sonal⋅Clapp, D W⋅Clapp, D.⋅Harrington, Maureen A and Harrington, Maureen
Experimental hematology, vol. 38, (no. 2), pp. 71-81, 2010/Feb. | Journal Article
 
Mast cells and the neurofibroma microenvironment.
Staser, Karl⋅Staser, Karl⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Clapp, D Wade and Clapp, D Wade
Blood, vol. 116, (no. 2), pp. 157-164, July 15, 2010. | Journal Article
 
Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.
Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅Burgin, Sarah⋅Burgin, Sarah⋅Burgin, Sarah⋅McDaniel, Andrew⋅McDaniel, Andrew⋅McDaniel, Andrew⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Xiaohong⋅Yuan, Jin⋅Yuan, Jin⋅Yuan, Jin⋅Chen, Mia⋅Chen, Mia⋅Chen, Mia⋅Khalaf, Waleed⋅Khalaf, Waleed⋅Khalaf, Waleed⋅Clapp, D. W⋅Clapp, D.⋅Clapp, D.⋅Yang, Feng Chun⋅Yang, Feng-Chun and Yang, Feng Chun
The American journal of pathology, vol. 177, (no. 6), pp. 3125-32, 2010/Dec. | Journal Article
 
Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells.
Staser, Karl⋅Staser, Karl⋅Yang, Feng Chun⋅Yang, Feng Chun⋅Clapp, D. W and Clapp, David
Current opinion in hematology, vol. 17, (no. 4), pp. 287-93, 2010/Jul. | Journal Article
2009
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.
Allen, Jayme D⋅Allen, Jayme D⋅Jaffer, Zahara M⋅Jaffer, Zahara M⋅Park, Su-Jung⋅Park, Su-Jung⋅Burgin, Sarah⋅Burgin, Sarah⋅Hofmann, Clemens⋅Hofmann, Clemens⋅Sells, Mary A⋅Sells, Mary Ann⋅Chen, Shi⋅Chen, Shi⋅Derr-Yellin, Ethel⋅Derr-Yellin, Ethel⋅Michels, Elizabeth G⋅Michels, Elizabeth G⋅McDaniel, Andrew⋅McDaniel, Andrew⋅Bessler, Waylan K⋅Bessler, Waylan K⋅Ingram, David A⋅Ingram, David A⋅Atkinson, Simon J⋅Atkinson, Simon J⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Chernoff, Jonathan⋅Chernoff, Jonathan⋅Clapp, D Wade and Clapp, D. W
Blood, vol. 113, (no. 12), pp. 2695-705, 2009/Mar/19. | Journal Article
2008
AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice.
Pulliam, Anna C⋅Pulliam, Anna⋅Hobson, M.⋅Hobson, M J⋅Ciccone, Samantha⋅Ciccone, Samantha L⋅Li, Yan⋅Li, Yan⋅Chen, Shi⋅Chen, Shi⋅Srour, Edward F⋅Srour, Edward⋅Yang, Feng Chun⋅Yang, Feng-Chun⋅Broxmeyer, Hal E⋅Broxmeyer, Hal⋅Clapp, D. and Clapp, D. W
Experimental hematology, vol. 36, (no. 9), pp. 1084-90, 2008/Sep. | Journal Article
 
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.
Yang, Feng Chun⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Ingram, David A⋅Ingram, David A⋅Ingram, David A⋅Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅Zhu, Yuan⋅Zhu, Yuan⋅Zhu, Yuan⋅Yuan, Jin⋅Yuan, Jin⋅Yuan, Jin⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Xiaohong⋅Yang, Xianlin⋅Yang, Xianlin⋅Yang, Xianlin⋅Knowles, Scott⋅Knowles, Scott⋅Knowles, Scott⋅Horn, Whitney⋅Horn, Whitney⋅Horn, Whitney⋅Li, Yan⋅Li, Yan⋅Li, Yan⋅Zhang, Shaobo⋅Zhang, Shaobo⋅Zhang, Shaobo⋅Yang, Yanzhu⋅Yang, Yanzhu⋅Yang, Yanzhu⋅Vakili, Saeed T⋅Vakili, Saeed T⋅Vakili, Saeed T⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Burns, Dennis⋅Burns, Dennis K⋅Burns, Dennis⋅Robertson, Kent⋅Robertson, Kent⋅Robertson, Kent⋅Hutchins, Gary⋅Hutchins, Gary⋅Hutchins, Gary⋅Parada, Luis F⋅Parada, Luis F⋅Parada, Luis F⋅Clapp, D. Wade⋅Clapp, D. W and Clapp, D. Wade
Cell, vol. 135, (no. 3), pp. 437-48, 2008/Oct/31. | Journal Article
 
Nf1-Dependent Tumors Require a Microenvironment Containing Nf1 super(+) super(/) super(-)- and c-kit-Dependent Bone Marrow
Yang, Feng Chun⋅Ingram, David A⋅Chen, S.⋅Zhu, Y.⋅Yuan, J.⋅Li, X.⋅Yang, X.⋅Knowles, S.⋅Horn, W.⋅Li, Y.⋅Zhang, S.⋅Yang, Y.⋅Vakili, ST⋅Yu, Menggang⋅Burns, Dennis K⋅Robertson, K.⋅Hutchins, G.⋅Parada, Luis F and Clapp, David W
Cell, vol. 135, (no. 3), pp. 437-448, 2008. | Journal Article
 
Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway
Lasater, Elisabeth A⋅Lasater, Elisabeth A.⋅Bessler, Waylan K⋅Bessler, Waylan K.⋅Mead, Laura E⋅Mead, Laura E.⋅Horn, Whitney E⋅Horn, Whitney E.⋅Clapp, D. Wade⋅Clapp, David W⋅Conway, Simon⋅Conway, Simon J.⋅Ingram, David A⋅Ingram, David A.⋅Li, Fang and Li, Fang
Human Molecular Genetics, vol. 17, (no. 15), pp. 2336-44, Aug 1, 2008. | Journal Article
 
Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells.
Si, Yue⋅Pulliam, Anna C⋅Linka, Yvonne⋅Ciccone, Samantha⋅Leurs, Cordula⋅Yuan, Jin⋅Eckermann, Olaf⋅Fruehauf, Stefan⋅Mooney, Sean⋅Hanenberg, Helmut and Clapp, D. W
Blood, vol. 112, (no. 12), pp. 4458-65, 2008/Dec/1. | Journal Article
 
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
McDaniel, Andrew S⋅McDaniel, Andrew S⋅Allen, Jayme D⋅Allen, Jayme D⋅Park, Su-Jung⋅Park, Su-Jung⋅Jaffer, Zahara M⋅Jaffer, Zahara M⋅Michels, Elizabeth G⋅Michels, Elizabeth G⋅Burgin, Sarah J⋅Burgin, Sarah J⋅Chen, Shi⋅Chen, Shi⋅Bessler, Waylan K⋅Bessler, Waylan K⋅Hofmann, Clemens⋅Hofmann, Clemens⋅Ingram, David A⋅Ingram, David A⋅Chernoff, Jonathan⋅Chernoff, Jonathan⋅Clapp, D Wade and Clapp, D. W
Blood, vol. 112, (no. 12), pp. 4646-54, 2008/Dec/1. | Journal Article
2007
Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment
Yang, Feng-Chun⋅Yang, Feng-Chun⋅Ingram, David⋅Ingram, David⋅Chen, Shi⋅Chen, Shi⋅Robertson, Kent⋅Robertson, Kent⋅Li, Xiohong⋅Li, Xiohong⋅Yuan, Jin⋅Yuan, Jin⋅Knoll, Scott⋅Knoll, Scott⋅Horn, Whitney⋅Horn, Whitney⋅Hutchins, Gary⋅Hutchins, Gary⋅Parada, L⋅Parada, L⋅Clapp, David Wade and Clapp, David Wade
Blood, vol. 110, (no. 11), pp. 1915, 2007-11-16. | Journal Article
2006
Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice.
Si, Yue⋅Ciccone, Samantha⋅Yang, Feng Chun⋅Yuan, Jin⋅Zeng, Daisy⋅Chen, Shi⋅van de Vrugt, Henri J⋅Critser, John⋅Arwert, Fre⋅Haneline, Laura S and Clapp, D. W
Blood, vol. 108, (no. 13), pp. 4283-7, 2006/Dec/15. | Journal Article
 
Developmental regulation of the immune system.
Clapp, D. W and Clapp, D. Wade
Seminars in perinatology, vol. 30, (no. 2), pp. 69-72, 2006/Apr. | Journal Article
 
HMGB1 expression and release by bone cells.
Charoonpatrapong, Kanokwan⋅Charoonpatrapong, Kanokwan⋅Shah, Rita⋅Shah, Rita⋅Robling, Alexander G.⋅Robling, Alexander⋅Alvarez, Marta⋅Alvarez, Marta⋅Clapp, D. Wade⋅Clapp, D W⋅Chen, Shi⋅Chen, Shi⋅Kopp, Ryan P⋅Kopp, Ryan P.⋅Pavalko, Fredrick M.⋅Pavalko, Fredrick M⋅Yu, Jun⋅Yu, Jun⋅Bidwell, Joseph and Bidwell, Joseph P.
Journal of cellular physiology, vol. 207, (no. 2), pp. 480-90, 2006/May. | Journal Article
 
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Yang, Feng Chun⋅Chen, Shi⋅Robling, Alexander⋅Yu, Xijie⋅Nebesio, Todd D⋅Yan, Jincheng⋅Morgan, Trent⋅Li, Xiaohong⋅Yuan, Jin⋅Hock, Janet⋅Ingram, David A and Clapp, D W
The Journal of clinical investigation, vol. 116, (no. 11), pp. 2880-91, 2006/Nov. | Journal Article
 
Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling.
Yang, Feng Chun⋅Chen, Shi⋅Clegg, Travis⋅Li, Xiaohong⋅Morgan, Trent⋅Estwick, Selina A⋅Yuan, Jin⋅Khalaf, Waleed⋅Burgin, Sarah⋅Travers, Jeff⋅Parada, Luis F⋅Ingram, David A and Clapp, D Wade
Human molecular genetics, vol. 15, (no. 16), pp. 2421-2437, August 15, 2006. | Journal Article
 
Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene
Hingtgen, Cynthia M⋅Roy, SL and Clapp, David W
Neuroscience, vol. 137, (no. 2), pp. 637-645, 2006. | Journal Article
2005
Ex Vivo culture of Fancc -/- bone marrow results in a time-dependent increase in apoptosis of stem/progenitor cells and selects for the genesis of cytogenetic abnormalities and hematologic malignancies
Li X, LeBeau MM, Ciccone SL, Yang FC, Freie BW, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW and Clapp, D. W
Blood, 2005. | Journal Article
 
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells.
Schubbert, Suzanne⋅Schubbert, Suzanne⋅Lieuw, Kenneth⋅Lieuw, Kenneth⋅Rowe, Sara L.⋅Rowe, Sara L⋅Lee, Connie M⋅Lee, Connie M.⋅Li, Xiaxin⋅Li, XiaXin⋅Loh, Mignon L⋅Loh, Mignon L.⋅Clapp, D. Wade⋅Clapp, D. W⋅Shannon, Kevin M and Shannon, Kevin M.
Blood, vol. 106, (no. 1), pp. 311-7, 2005/Jul/1. | Journal Article
 
Granulocyte/macrophage colony-stimulating factor and accessory cells modulate radioprotection by purified hematopoietic cells
Katsumoto, Tamiko R⋅Katsumoto TR,, Duda J, Kim A, Wardak Z, Dranoff G, Clapp DW, Shannon K⋅Duda, Jennifer⋅Kim, Andrew⋅Wardak, Zabihullah⋅Dranoff, Glenn⋅Clapp, D Wade⋅Shannon, Kevin and Clapp, D. W
Journal of Experimental Medicine, vol. 201, pp. 853-858, 2005. | Journal Article
 
Granulocyte/macrophage colony-stimulating factor and accessory cells modulate radioprotection by purified hematopoietic cells.
Katsumoto, Tamiko⋅Katsumoto, Tamiko R.⋅Duda, Jennifer⋅Duda, Jennifer⋅Kim, Andrew⋅Kim, Andrew⋅Wardak, Zabihullah⋅Wardak, Zabihullah⋅Dranoff, Glenn⋅Dranoff, Glenn⋅Clapp, D. Wade⋅Clapp, D. W⋅Shannon, Kevin M and Shannon, Kevin
The Journal of experimental medicine, vol. 201, (no. 6), pp. 853-8, 2005/Mar/21. | Journal Article
 
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF and Clapp, D. W
Journal of Experimental Medicine, vol. 210, (no. 8), pp. 1307-18, 2005. | Journal Article