Using mouse models, the Flak Lab is working to identify the neural circuits, as well as the essential components (e.g. receptors, transmitters, transcription factors) within these circuits, that are responsible for generating these responses.
Concurrently, the Flak Lab also aims to understand the circuits in the brain that separately control energy expenditure, especially those circuits that can be promoted during periods of exercise.
Dr. Flak is working to establish the downstream connections from the hypothalamus to understand how these signals communicate with the peripheral organs in order to generate the mobilization of blood glucose, glucose uptake and facilitate energy expenditure.
Research: Cellular and Molecular Metabolism
