11 Publications
2014
Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715.
Slee, Roger B⋅Slee, Roger B⋅Grimes, Brenda R⋅Grimes, Brenda⋅Bansal, Ruchi⋅Bansal, Ruchi⋅Gore, Jesse⋅Gore, Jesse⋅Blackburn, Corinne⋅Blackburn, Corinne⋅Brown, Lyndsey⋅Brown, Lyndsey⋅Gasaway, Rachel⋅Gasaway, Rachel⋅Jeong, Jaesik⋅Jeong, Jaesik⋅Victorino, Jose⋅Victorino, Jose⋅March, Keith L⋅March, Keith L⋅Colombo, Riccardo⋅Colombo, Riccardo⋅Herbert, Brittney-Shea⋅Herbert, Brittney Shea⋅Korc, Murray and Korc, Murray
Molecular cancer therapeutics, vol. 13, (no. 2), pp. 307-15, 2014/Feb. | Journal Article
2009
Interphase FISH demonstrates that human adipose stromal cells maintain a high level of genomic stability in long-term culture.
Grimes, Brenda R⋅Grimes, Brenda⋅Grimes, Brenda R⋅Grimes, Brenda R⋅Steiner, Camie M⋅Steiner, Camie M⋅Steiner, Camie M⋅Steiner, Camie M⋅Merfeld-Clauss, Stephanie⋅Merfeld-Clauss, Stephanie⋅Merfeld-Clauss, Stephanie⋅Merfeld-Clauss, Stephanie⋅Traktuev, Dmitry O⋅Traktuev, Dmitry O⋅Traktuev, Dmitry O⋅Traktuev, Dmitry O⋅Smith, Danielle⋅Smith, Danielle⋅Smith, Danielle⋅Smith, Danielle⋅Reese, Angela⋅Reese, Angela⋅Reese, Angela⋅Reese, Angela⋅Breman, Amy M⋅Breman, Amy M⋅Breman, Amy M⋅Breman, Amy M⋅Thurston, Virginia C⋅Thurston, Virginia C⋅Thurston, Virginia C⋅Thurston, Virginia C⋅Vance, Gail H⋅Vance, Gail H⋅Vance, Gail H⋅Vance, Gail H⋅Johnstone, Brian⋅Johnstone, Brian H⋅Johnstone, Brian H⋅Johnstone, Brian H⋅Slee, Roger B⋅Slee, Roger B⋅Slee, Roger B⋅Slee, Roger B⋅March, Keith L⋅March, Keith L⋅March, Keith L and March, Keith L
Stem cells and development, vol. 18, (no. 5), pp. 717-24, 2009/Jun. | Journal Article
2008
Identifying and genotyping transgene integration loci
Liang, Zhong⋅Liang, Zhong⋅Breman, Amy⋅Breman, Amy M⋅Grimes, Brenda⋅Grimes, Brenda⋅Rosen, Elliot D and Rosen, Elliot
Transgenic research., vol. 17, (no. 5), pp. 979-983, 2008. | Journal Article
 
Input DNA ratio determines copy number of the 33 kb Factor IX gene on de novo human artificial chromosomes.
Breman, Amy M⋅Breman, Amy M⋅Steiner, Camie M⋅Steiner, Camie M⋅Slee, Roger B⋅Slee, Roger B⋅Grimes, Brenda R and Grimes, Brenda
Molecular therapy : the journal of the American Society of Gene Therapy, vol. 16, (no. 2), pp. 315-23, 2008/Feb. | Journal Article
2005
Artificial and engineered chromosomes: developments and prospects for gene therapy
Grimes, Brenda and Monaco, Zoia L
Chromosoma, vol. 114, (no. 4), pp. 230-241, 2005. | Journal Article
2004
Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes.
Grimes, Brenda⋅Babcock, Jennifer⋅Rudd, M K⋅Chadwick, Brian P and Willard, Huntington F
Genome biology , vol. 5, (no. 11), pp. R89, 2004. | Journal Article
2002
Alpha-satellite DNA and vector composition influence rates of human artificial chromosome formation.
Grimes, Brenda⋅Rhoades, Angela A and Willard, Huntington F
Molecular therapy : the journal of the American Society of Gene Therapy, vol. 5, (no. 6), pp. 798-805, 2002/Jun. | Journal Article
 
Chromosome engineering: prospects for gene therapy
Grimes, Brenda⋅Warburton, Peter E and Farr, C. J
Gene Therapy, vol. 9, (no. 11), pp. 713-718, Jun 2002. | Journal Article
 
Chromosome engineering: prospects for gene therapy
Grimes, B⋅Warburton, P and Farr, C
Gene Therapy, vol. 9, (no. 11), pp. 713-8, Jun 2002. | Journal Article
2001
Stable gene expression from a mammalian artificial chromosome
Grimes, Brenda⋅Schindelhauer, Dirk⋅McGill, Nio I⋅Ross, Andrew⋅Ebersole, Thomas A and Cooke, Howard J
EMBO Reports, vol. 2, (no. 10), pp. 910, Oct 15, 2001. | Journal Article
2000
Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats
Ebersole, Thomas A⋅Ross, Andrew⋅Clark, Elma⋅McGill, Niolette⋅Schindelhauer, Dirk⋅Cooke, Howard and Grimes, Brenda
Human Molecular Genetics, vol. 9, (no. 11), pp. 1623, Jul 1, 2000. | Journal Article