97 Publications (Page 1 of 4)
2018
Crk proteins transduce FGF signaling to promote lens fiber cell elongation
Collins, Tamica N⋅Mao, Yingyu⋅Li, Hongge⋅Bouaziz, Michael⋅Hong, Angela⋅Feng, Gen-Sheng⋅Wang, Fen⋅Quilliam, Lawrence A⋅Chen, Lin⋅Park, Taeju⋅Curran, Tom and Zhang, Xin
eLife, vol. 7, 2018-01-23. | Journal Article
2016
A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation
Sana, Maria⋅Quilliam, Lawrence⋅Spitaleri, Andrea⋅Pezzoli, Laura⋅Marchetti, Daniela⋅Lodrini, Chiara⋅Candiago, Elisabetta⋅Lincesso, Anna⋅Ferrazzi, Paolo and Iascone, Maria
PLoS One, vol. 11, (no. 12), Dec 2016. | Journal Article
 
Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
Wang, Haibo⋅Han, Xiaokun⋅Bretz, Colin⋅Becker, Silke⋅Gambhir, Deeksha⋅Smith, George⋅Samulski, R⋅Wittchen, Erika⋅Quilliam, Lawrence⋅Chrzanowska-wodnicka, Magdalena and Hartnett, M
Molecular Therapy. Methods & Clinical Development, vol. 3, pp. 16056, Aug 2016. | Journal Article
2015
Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.
Birukova, Anna A⋅Meng, Fanyong⋅Tian, Yufeng⋅Meliton, Angelo⋅Sarich, Nicolene⋅Quilliam, Lawrence A and Birukov, Konstantin G
Biochimica et biophysica acta, vol. 1852, (no. 5), pp. 778-791, May 2015. | Journal Article
 
Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature
Chrzanowska-Wodnicka, Magdalena⋅Chrzanowska-Wodnicka, Magdalena⋅White, Gilbert⋅II, Gilbert⋅White, Gilbert C⋅Quilliam, Lawrence⋅Quilliam, Lawrence⋅Whitehead, Kevin and Whitehead, Kevin
PLoS One, vol. 10, (no. 12), Dec 2015. | Journal Article
2014
Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
Wang, Haibo⋅Jiang, Yanchao⋅Shi, Dallas⋅Quilliam, Lawrence A⋅Chrzanowska-Wodnicka, Magdalena⋅Wittchen, Erika S⋅Li, Dean and Hartnett, M E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 28, (no. 1), pp. 265-74, 2014/Jan. | Journal Article
 
The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.
Sayyah, Jacqueline⋅Bartakova, Alena⋅Nogal, Nekeisha⋅Quilliam, Lawrence A⋅Stupack, Dwayne G and Brown, Joan Heller
The Journal of biological chemistry, vol. 289, (no. 25), pp. 17689-17698, June 20, 2014. | Journal Article
2013
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, H. B⋅Babcock, J. T⋅Wells, Clark D and Quilliam, Lawrence A
Oncogene, vol. 32, (no. 35), pp. 4100-9, Aug 29, 2013. | Journal Article
 
Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
Babcock, Justin T⋅Nguyen, Hoa B⋅He, Yujun⋅Hendricks, Jeremiah W⋅Wek, Ronald C and Quilliam, Lawrence A
The Journal of biological chemistry, vol. 288, (no. 22), pp. 15687-98, 2013/May/31. | Journal Article
 
PI3-Kinase gamma Promotes Rap1a-Mediated Activation of Myeloid Cell Integrin alpha 4 beta 1, Leading to Tumor Inflammation and Growth. e60226
Schmid, Michael C⋅Schmid, M.C.⋅Schmid, M.C.⋅Franco, I.⋅Franco, Irene⋅Franco, I.⋅Kang, S.W.⋅Kang, S.W.⋅Kang, Sang W⋅Hirsch, E.⋅Hirsch, Emilio⋅Hirsch, E.⋅Quilliam, L.A.⋅Quilliam, L.A.⋅Quilliam, Lawrence A⋅Varner, J.A.⋅Varner, Judith A and Varner, J.A.
PLoS ONE, vol. 8, (no. 4), 2013. | Journal Article
 
PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
Schmid, Michael C⋅Franco, Irene⋅Kang, Sang W⋅Hirsch, Emilio⋅Quilliam, Lawrence A and Varner, Judith A
PloS one, vol. 8, (no. 4), pp. e60226, 2013. | Journal Article
 
Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.
Wittchen, Erika S⋅Nishimura, Eiichi⋅McCloskey, Manabu⋅Wang, Haibo⋅Quilliam, Lawrence A⋅Chrzanowska-Wodnicka, Magdalena and Hartnett, M Elizabeth
PloS one, vol. 8, (no. 9), pp. e73070, 2013. | Journal Article
2012
Abstract LB-247: mTORC1 enhances bortezomib-induced death in TSC-null cells by a c-MYC-dependent induction of the unfolded protein response
Babcock, Justin T⋅Babcock, Justin T⋅Nguen, Hoa B⋅Nguen, Hoa B⋅He, Yujun⋅He, Yujun⋅Wek, Ronald C⋅Wek, Ronald C⋅Quilliam, Lawrence A and Quilliam, Lawrence A
Cancer Research, vol. 72, (no. 8 Supplement), pp. LB-247, 2012-04-15. | Journal Article
 
Abstract LB-29: LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, Hoa B⋅Nguyen, Hoa B⋅Babcock, Justin T⋅Babcock, Justin T⋅Wells, Clark D⋅Wells, Clark D⋅Quilliam, Lawrence A and Quilliam, Lawrence A
Cancer Research, vol. 72, (no. 8 Supplement), pp. LB-29, 2012-04-15. | Journal Article
 
Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells.
Crotzer, Victoria L⋅Crotzer, Victoria L.⋅Matute, Juan D.⋅Matute, Juan D⋅Arias, Andrés A⋅Arias, Andrés A.⋅Zhao, Heng⋅Zhao, Heng⋅Quilliam, Lawrence A.⋅Quilliam, Lawrence A⋅Dinauer, Mary C.⋅Dinauer, Mary C⋅Blum, Janice S. and Blum, Janice S
Journal of immunology (Baltimore, Md. : 1950), vol. 189, (no. 8), pp. 3800-4, 2012/Oct/15. | Journal Article
 
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells.
Jeyaraj, Selvi C⋅Unger, Nicholas T⋅Eid, Ali H⋅Mitra, Srabani⋅Paul El-Dahdah, N⋅Quilliam, Lawrence A⋅Flavahan, Nicholas A and Chotani, Maqsood A
American journal of physiology. Cell physiology, vol. 303, (no. 5), pp. C499-511, 2012/Sep/1. | Journal Article
 
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Siroky, Brian J⋅Yin, Hong⋅Babcock, Justin T⋅Lu, Lu⋅Hellmann, Anna R⋅Dixon, Bradley P⋅Quilliam, Lawrence A and Bissler, John J
American journal of physiology. Renal physiology, vol. 303, (no. 6), pp. F831-44, 2012/Sep/15. | Journal Article
 
M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.
Castro, Ariel F⋅Campos, Tania⋅Babcock, Justin T⋅Armijo, Marisol E⋅Martínez-Conde, Alfonso⋅Pincheira, Roxana and Quilliam, Lawrence A
Journal of cellular biochemistry, vol. 113, (no. 4), pp. 1253-64, 2012/Apr. | Journal Article
2011
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
Kepner, E. M.⋅Kepner, Erica M⋅Yoder, S. M.⋅Yoder, Stephanie M⋅Oh, E.⋅Oh, Eunjin⋅Kalwat, Michael A⋅Kalwat, M. A.⋅Wang, Zhanxiang⋅Wang, Z.⋅Quilliam, Lawrence A⋅Quilliam, L. A.⋅Thurmond, D. C. and Thurmond, Debbie
American journal of physiology. Endocrinology and metabolism, vol. 301, (no. 6), pp. E1072-80, 2011/Dec. | Journal Article
 
PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
Bai, Yunpeng⋅Bai, Yunpeng⋅Bai, Yunpeng⋅Luo, Yong⋅Luo, Yong⋅Luo, Yong⋅Liu, Sijiu⋅Liu, Sijiu⋅Liu, Sijiu⋅Zhang, Lujuan⋅Zhang, Lujuan⋅Zhang, Lujuan⋅Shen, Kui⋅Shen, Kui⋅Shen, Kui⋅Dong, Yuanshu⋅Dong, Yuanshu⋅Dong, Yuanshu⋅Walls, Chad D⋅Walls, Chad D⋅Walls, Chad D.⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A.⋅Quilliam, Lawrence A⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D.⋅Cao, Youjia⋅Cao, Youjia⋅Cao, Youjia⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin and Zhang, Z. F
The Journal of biological chemistry, vol. 286, (no. 49), pp. 42316-24, 2011/Dec/9. | Journal Article
 
Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Babcock, Justin T and Quilliam, Lawrence A
Current drug targets, vol. 12, (no. 8), pp. 1223-31, 2011/Jul/1. | Journal Article
2010
Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by β3 integrin signaling
Panchatcharam, Manikandan⋅Panchatcharam, Manikandan⋅Miriyala, Sumitra⋅Miriyala, Sumitra⋅Yang, Fanmuyi⋅Yang, Fanmuyi⋅Leitges, Michael⋅Leitges, Michael⋅Chrzanowska-Wodnicka, Magdalena⋅Wodnicka, Magdalena⋅Chrzanowska-Wodnicka, Magdalena⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A⋅Anaya, Paul⋅Anaya, Paul⋅Morris, Andrew J⋅Morris, Andrew J⋅Smyth, Susan S and Smyth, Susan S
International Journal of Biochemistry and Cell Biology, vol. 42, (no. 6), pp. 974, 2010. | Journal Article
 
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
Awasthi, Aradhana⋅Samarakoon, Asanga⋅Chu, Haiyan⋅Kamalakannan, Rajasekaran⋅Quilliam, Lawrence A⋅Chrzanowska Wodnicka, Magdalena⋅White, Gilbert C and Malarkannan, Subramaniam
Journal of Experimental Medicine, vol. 207, (no. 9), pp. 1923-1938, 2010. | Journal Article
2009
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines.
Woolfrey, Kevin M⋅Woolfrey, Kevin M⋅Srivastava, Deepak P⋅Srivastava, Deepak⋅Photowala, Huzefa⋅Photowala, Huzefa⋅Yamashita, Megumi⋅Yamashita, Megumi⋅Barbolina, Maria V⋅Barbolina, Maria V⋅Cahill, Michael E⋅Cahill, Michael E⋅Xie, Zhong⋅Xie, Zhong⋅Jones, Kelly A⋅Jones, Kelly A⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A⋅Prakriya, Murali⋅Prakriya, Murali⋅Penzes, Peter and Penzes, Peter
Nature neuroscience, vol. 12, (no. 10), pp. 1275-84, 2009/Oct. | Journal Article
2008
E-cadherin dis-engagement activates the Rap1 GTPase.
Asuri, Sirisha⋅Yan, Jingliang⋅Paranavitana, Nivanka C and Quilliam, Lawrence A
Journal of cellular biochemistry, vol. 105, (no. 4), pp. 1027-37, 2008/Nov/1. | Journal Article