97 Publications (Page 1 of 4)
Crk proteins transduce FGF signaling to promote lens fiber cell elongation
Collins, Tamica NMao, YingyuLi, HonggeBouaziz, MichaelHong, AngelaFeng, Gen-ShengWang, FenQuilliam, Lawrence AChen, LinPark, TaejuCurran, Tom and Zhang, Xin
eLife, vol. 7, 2018-01-23. | Journal Article
A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation
Sana, MariaQuilliam, LawrenceSpitaleri, AndreaPezzoli, LauraMarchetti, DanielaLodrini, ChiaraCandiago, ElisabettaLincesso, AnnaFerrazzi, Paolo and Iascone, Maria
PLoS One, vol. 11, (no. 12), Dec 2016. | Journal Article
Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
Wang, HaiboHan, XiaokunBretz, ColinBecker, SilkeGambhir, DeekshaSmith, GeorgeSamulski, RWittchen, ErikaQuilliam, LawrenceChrzanowska-wodnicka, Magdalena and Hartnett, M
Molecular Therapy. Methods & Clinical Development, vol. 3, pp. 16056, Aug 2016. | Journal Article
Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.
Birukova, Anna AMeng, FanyongTian, YufengMeliton, AngeloSarich, NicoleneQuilliam, Lawrence A and Birukov, Konstantin G
Biochimica et biophysica acta, vol. 1852, (no. 5), pp. 778-791, May 2015. | Journal Article
Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature
Chrzanowska-Wodnicka, MagdalenaChrzanowska-Wodnicka, MagdalenaWhite, GilbertII, GilbertWhite, Gilbert CQuilliam, LawrenceQuilliam, LawrenceWhitehead, Kevin and Whitehead, Kevin
PLoS One, vol. 10, (no. 12), Dec 2015. | Journal Article
Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
Wang, HaiboJiang, YanchaoShi, DallasQuilliam, Lawrence AChrzanowska-Wodnicka, MagdalenaWittchen, Erika SLi, Dean and Hartnett, M E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 28, (no. 1), pp. 265-74, 2014/Jan. | Journal Article
The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.
Sayyah, JacquelineBartakova, AlenaNogal, NekeishaQuilliam, Lawrence AStupack, Dwayne G and Brown, Joan Heller
The Journal of biological chemistry, vol. 289, (no. 25), pp. 17689-17698, June 20, 2014. | Journal Article
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, H. BBabcock, J. TWells, Clark D and Quilliam, Lawrence A
Oncogene, vol. 32, (no. 35), pp. 4100-9, Aug 29, 2013. | Journal Article
Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
Babcock, Justin TNguyen, Hoa BHe, YujunHendricks, Jeremiah WWek, Ronald C and Quilliam, Lawrence A
The Journal of biological chemistry, vol. 288, (no. 22), pp. 15687-98, 2013/May/31. | Journal Article
PI3-Kinase gamma Promotes Rap1a-Mediated Activation of Myeloid Cell Integrin alpha 4 beta 1, Leading to Tumor Inflammation and Growth. e60226
Schmid, Michael CSchmid, M.C.Schmid, M.C.Franco, I.Franco, IreneFranco, I.Kang, S.W.Kang, S.W.Kang, Sang WHirsch, E.Hirsch, EmilioHirsch, E.Quilliam, L.A.Quilliam, L.A.Quilliam, Lawrence AVarner, J.A.Varner, Judith A and Varner, J.A.
PLoS ONE, vol. 8, (no. 4), 2013. | Journal Article
PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
Schmid, Michael CFranco, IreneKang, Sang WHirsch, EmilioQuilliam, Lawrence A and Varner, Judith A
PloS one, vol. 8, (no. 4), pp. e60226, 2013. | Journal Article
Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.
Wittchen, Erika SNishimura, EiichiMcCloskey, ManabuWang, HaiboQuilliam, Lawrence AChrzanowska-Wodnicka, Magdalena and Hartnett, M Elizabeth
PloS one, vol. 8, (no. 9), pp. e73070, 2013. | Journal Article
Abstract LB-247: mTORC1 enhances bortezomib-induced death in TSC-null cells by a c-MYC-dependent induction of the unfolded protein response
Babcock, Justin TBabcock, Justin TNguen, Hoa BNguen, Hoa BHe, YujunHe, YujunWek, Ronald CWek, Ronald CQuilliam, Lawrence A and Quilliam, Lawrence A
Cancer Research, vol. 72, (no. 8 Supplement), pp. LB-247, 2012-04-15. | Journal Article
Abstract LB-29: LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, Hoa BNguyen, Hoa BBabcock, Justin TBabcock, Justin TWells, Clark DWells, Clark DQuilliam, Lawrence A and Quilliam, Lawrence A
Cancer Research, vol. 72, (no. 8 Supplement), pp. LB-29, 2012-04-15. | Journal Article
Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells.
Crotzer, Victoria LCrotzer, Victoria L.Matute, Juan D.Matute, Juan DArias, Andrés AArias, Andrés A.Zhao, HengZhao, HengQuilliam, Lawrence A.Quilliam, Lawrence ADinauer, Mary C.Dinauer, Mary CBlum, Janice S. and Blum, Janice S
Journal of immunology (Baltimore, Md. : 1950), vol. 189, (no. 8), pp. 3800-4, 2012/Oct/15. | Journal Article
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells.
Jeyaraj, Selvi CUnger, Nicholas TEid, Ali HMitra, SrabaniPaul El-Dahdah, NQuilliam, Lawrence AFlavahan, Nicholas A and Chotani, Maqsood A
American journal of physiology. Cell physiology, vol. 303, (no. 5), pp. C499-511, 2012/Sep/1. | Journal Article
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Siroky, Brian JYin, HongBabcock, Justin TLu, LuHellmann, Anna RDixon, Bradley PQuilliam, Lawrence A and Bissler, John J
American journal of physiology. Renal physiology, vol. 303, (no. 6), pp. F831-44, 2012/Sep/15. | Journal Article
M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.
Castro, Ariel FCampos, TaniaBabcock, Justin TArmijo, Marisol EMartínez-Conde, AlfonsoPincheira, Roxana and Quilliam, Lawrence A
Journal of cellular biochemistry, vol. 113, (no. 4), pp. 1253-64, 2012/Apr. | Journal Article
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
Kepner, E. M.Kepner, Erica MYoder, S. M.Yoder, Stephanie MOh, E.Oh, EunjinKalwat, Michael AKalwat, M. A.Wang, ZhanxiangWang, Z.Quilliam, Lawrence AQuilliam, L. A.Thurmond, D. C. and Thurmond, Debbie
American journal of physiology. Endocrinology and metabolism, vol. 301, (no. 6), pp. E1072-80, 2011/Dec. | Journal Article
PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
Bai, YunpengBai, YunpengBai, YunpengLuo, YongLuo, YongLuo, YongLiu, SijiuLiu, SijiuLiu, SijiuZhang, LujuanZhang, LujuanZhang, LujuanShen, KuiShen, KuiShen, KuiDong, YuanshuDong, YuanshuDong, YuanshuWalls, Chad DWalls, Chad DWalls, Chad D.Quilliam, Lawrence AQuilliam, Lawrence A.Quilliam, Lawrence AWells, Clark DWells, Clark DWells, Clark D.Cao, YoujiaCao, YoujiaCao, YoujiaZhang, Zhong-YinZhang, Zhong-Yin and Zhang, Z. F
The Journal of biological chemistry, vol. 286, (no. 49), pp. 42316-24, 2011/Dec/9. | Journal Article
Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Babcock, Justin T and Quilliam, Lawrence A
Current drug targets, vol. 12, (no. 8), pp. 1223-31, 2011/Jul/1. | Journal Article
Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by β3 integrin signaling
Panchatcharam, ManikandanPanchatcharam, ManikandanMiriyala, SumitraMiriyala, SumitraYang, FanmuyiYang, FanmuyiLeitges, MichaelLeitges, MichaelChrzanowska-Wodnicka, MagdalenaWodnicka, MagdalenaChrzanowska-Wodnicka, MagdalenaQuilliam, Lawrence AQuilliam, Lawrence AAnaya, PaulAnaya, PaulMorris, Andrew JMorris, Andrew JSmyth, Susan S and Smyth, Susan S
International Journal of Biochemistry and Cell Biology, vol. 42, (no. 6), pp. 974, 2010. | Journal Article
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
Awasthi, AradhanaSamarakoon, AsangaChu, HaiyanKamalakannan, RajasekaranQuilliam, Lawrence AChrzanowska Wodnicka, MagdalenaWhite, Gilbert C and Malarkannan, Subramaniam
Journal of Experimental Medicine, vol. 207, (no. 9), pp. 1923-1938, 2010. | Journal Article
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines.
Woolfrey, Kevin MWoolfrey, Kevin MSrivastava, Deepak PSrivastava, DeepakPhotowala, HuzefaPhotowala, HuzefaYamashita, MegumiYamashita, MegumiBarbolina, Maria VBarbolina, Maria VCahill, Michael ECahill, Michael EXie, ZhongXie, ZhongJones, Kelly AJones, Kelly AQuilliam, Lawrence AQuilliam, Lawrence APrakriya, MuraliPrakriya, MuraliPenzes, Peter and Penzes, Peter
Nature neuroscience, vol. 12, (no. 10), pp. 1275-84, 2009/Oct. | Journal Article
E-cadherin dis-engagement activates the Rap1 GTPase.
Asuri, SirishaYan, JingliangParanavitana, Nivanka C and Quilliam, Lawrence A
Journal of cellular biochemistry, vol. 105, (no. 4), pp. 1027-37, 2008/Nov/1. | Journal Article