Control of the antibody response by follicular helper cells (TFH cells) and follicular regulatory T cells (TFR cells), particularly in the context of autoimmunity and allergy.
Control of TFH and TFR cell responses by transcription factors, particularly the transcriptional repressor Bcl6.
Regulation CD4 and CD8 T cell memory by the transcriptional repressor Bcl6.
Metabolic control of TFH and TFR cell responses.
Infection of TFH cells by HIV relevant to HIV latency.
Enhancing vaccine repsonses via modulation of TFH and TFR cells.
The role of Bcl6 in germinal center B cells and B cell lymphoma.
Dr. Dent's research interests include:
- Interested in the growth and differentiation of lymphocytes.
Expertise: Microbiology & Immunology