30 Publications (Page 1 of 2)
2012
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity.Ramalingam, L.⋅Ramalingam, Latha⋅Oh, E.⋅Oh, Eunjin⋅Yoder, S. M.⋅Yoder, Stephanie M⋅Brozinick, Joseph T⋅Brozinick, J. T.⋅Kalwat, M. A.⋅Kalwat, Michael A⋅Groffen, A. J.⋅Groffen, Alexander J⋅Verhage, M.⋅Verhage, Matthijs⋅Thurmond, Debbie and Thurmond, D. C.Diabetes, vol. 61, (no. 10), pp. 2424-32, 2012/Oct.
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Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.Kalwat, Michael A⋅Kalwat, M. A.⋅Wiseman, D. A.⋅Wiseman, Dean A⋅Luo, Wei⋅Luo, W.⋅Wang, Z.⋅Wang, Zhanxiang⋅Thurmond, D. C. and Thurmond, DebbieMolecular endocrinology (Baltimore, Md.), vol. 26, (no. 1), pp. 128-41, 2012/Jan.
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2011
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.Kepner, E. M.⋅Kepner, Erica M⋅Yoder, S. M.⋅Yoder, Stephanie M⋅Oh, E.⋅Oh, Eunjin⋅Kalwat, Michael A⋅Kalwat, M. A.⋅Wang, Zhanxiang⋅Wang, Z.⋅Quilliam, Lawrence A⋅Quilliam, L. A.⋅Thurmond, D. C. and Thurmond, DebbieAmerican journal of physiology. Endocrinology and metabolism, vol. 301, (no. 6), pp. E1072-80, 2011/Dec.
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Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosisJewell, Jenna L⋅Jewell, J. L.⋅Oh, Eunjin⋅Oh, E.⋅Ramalingam, Latha⋅Ramalingam, L.⋅Kalwat, Michael A⋅Kalwat, M. A.⋅Tagliabracci, Vincent S⋅Tagliabracci, V. S.⋅Tackett, L.⋅Tackett, Lixuan⋅Elmendorf, Jeffrey S⋅Elmendorf, J. S.⋅Thurmond, D. C. and Thurmond, DebbieThe Journal of Cell Biology, vol. 193, (no. 1), Apr 4, 2011.
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2010
Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4Jewell, Jenna L⋅Oh, Eunjin and Thurmond, DebbieAmerican Journal of Physiology, vol. 298, (no. 3), Mar 2010.
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2009
Insulin-regulated glucagon-like peptide-1 release from L cells: actin' out.Thurmond, DebbieEndocrinology, vol. 150, (no. 12), pp. 5202-4, 2009/Dec.
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Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins.Wang, Zhanxiang and Thurmond, DebbieJournal of cell science, vol. 122, (no. Pt 7), pp. 893-903, 2009/Apr/1.
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Munc18c depletion selectively impairs the sustained phase of insulin release.Oh, Eunjin and Thurmond, DebbieDiabetes, vol. 58, (no. 5), pp. 1165-74, 2009/May.
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2008
Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4.Jewell, Jenna L⋅Luo, Wei⋅Oh, Eunjin⋅Wang, Zhanxiang and Thurmond, DebbieJournal of biological chemistry., vol. 283, (no. 16), pp. 10716-10726, 2008.
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2007
Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion.Wang, Zhanxiang⋅Oh, Eunjin and Thurmond, DebbieThe Journal of biological chemistry, vol. 282, (no. 13), pp. 9536-46, 2007/Mar/30.
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2006
Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells.Spurlin, Beth A and Thurmond, Debbie CMolecular endocrinology (Baltimore, Md.), vol. 20, (no. 1), pp. 183-193, January 2006.
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The Stimulus-induced Tyrosine Phosphorylation of Munc18c Facilitates Vesicle ExocytosisOh, Eunjin and Thurmond, DebbieJournal of biological chemistry., vol. 281, (no. 26), pp. 17624-17634, 2006.
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2005
Munc18c Heterozygous Knockout Mice Display Increased Susceptibility for Severe Glucose IntoleranceOh, Eunjin⋅Spurlin, Beth A⋅Pessin, Jeffrey E and Thurmond, DebbieDiabetes, vol. 54, (no. 3), pp. 638-647, 2005.
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Syntaxin 4 Facilitates Biphasic Insulin Secretion in Pancreatic Beta CellsSpurlin, Beth A and Thurmond, DebbieDiabetes, vol. 54, pp. A45, Jun 2005.
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2004
Platelets from Munc18c heterozygous mice exhibit normal stimulus-induced release.Schraw, Todd D⋅Crawford, Garland L⋅Ren, Qiansheng⋅Choi, Wangsun⋅Thurmond, Debbie⋅Pessin, Jeffery and Whiteheart, Sidney WThrombosis and haemostasis, vol. 92, (no. 4), pp. 829-37, 2004/Oct.
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Syntaxin 4 Transgenic Mice Exhibit Enhanced Insulin-Mediated Glucose Uptake in Skeletal MuscleSpurlin, Beth A⋅Park, So-Young⋅Nevins, Angela K⋅Kim, Jason K and Thurmond, DebbieDiabetes, vol. 53, (no. 9), pp. 2223-31, Sep 2004.
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2003
Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c.Chen, Guoli⋅Liu, Ping⋅Thurmond, Debbie and Elmendorf, Jeffrey SFEBS letters, vol. 534, (no. 1-3), pp. 54-60, 2003/Jan/16.
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Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretionNevins, Angela K and Thurmond, DebbieAmerican Journal of Physiology, vol. 54, (no. 3), pp. C698-C710, Sep 2003.
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Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion.Nevins, Angela K and Thurmond, DebbieAmerican journal of physiology. Cell physiology, vol. 285, (no. 3), pp. C698-710, 2003/Sep.
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Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex.DC, Thurmond⋅Thurmond, Debbie⋅Gonelle Gispert, Carmen⋅C, Gonelle-Gispert⋅Furukawa, Megumi⋅M, Furukawa⋅Halban, Philippe A⋅PA, Halban⋅JE, Pessin and Pessin, Jeffrey EMolecular endocrinology (Baltimore, Md.), vol. 17, (no. 4), pp. 732-42, 2003/Apr.
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Insulin resistance in tetracycline-repressible Munc18c transgenic mice.Spurlin, Beth A⋅Thomas, Rhonda M⋅Nevins, Angela K⋅Kim, Hyo-Jeong⋅Kim, Yoon-Jung⋅Noh, Hye-Lim⋅Shulman, Gerald I⋅Kim, Jason K and Thurmond, DebbieDiabetes, vol. 52, (no. 8), pp. 1910-7, 2003/Aug.
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2001
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10.Chiang, S.-H.⋅Chiang, S H⋅Chiang, S.-H.⋅Chiang, S.-H.⋅Baumann, C.A.⋅Baumann, C.A.⋅Baumann, C.A.⋅Baumann, C A⋅Kanzaki, M.⋅Kanzaki, M⋅Kanzaki, M.⋅Kanzaki, M.⋅Thurmond, D.C.⋅Thurmond, D.C.⋅Thurmond, Debbie⋅Thurmond, D.C.⋅Watson, R T⋅Watson, R.T.⋅Watson, R.T.⋅Watson, R.T.⋅Neudauer, C.L.⋅Neudauer, C.L.⋅Neudauer, C.L.⋅Neudauer, C L⋅Macara, I G⋅Macara, I.G.⋅Macara, I.G.⋅Macara, I.G.⋅Pessin, J.E.⋅Pessin, J.E.⋅Pessin, Jeffrey E⋅Pessin, J.E.⋅Saltiel, Alan R⋅Saltiel, A.R.⋅Saltiel, A.R. and Saltiel, A.R.Nature, vol. 410, (no. 6831), pp. 944-8, 2001/Apr/19.
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Molecular machinery involved in the insulin-regulated fusion of GLUT4-containing vesicles with the plasma membrane (review).Thurmond, Debbie and Pessin, Jeffrey EMolecular membrane biology, vol. 18, (no. 4), pp. 237-45, 2001 Oct-Dec.
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Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle.Khan, A H⋅Thurmond, Debbie⋅Yang, C⋅Ceresa, Brian P⋅Sigmund, Curt D and Pessin, Jeffrey EThe Journal of biological chemistry, vol. 276, (no. 6), pp. 4063-9, 2001/Feb/9.
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Syntaxin 4 heterozygous knockout mice develop muscle insulin resistanceYang, C.⋅Coker, KJ⋅Kim, Jason K⋅Mora, Silvia⋅Thurmond, Debbie⋅Davis, AC⋅Yang, B.⋅Williamson, RA⋅Shulman, Gerald I and Pessin, Jeffrey EJournal of Clinical Investigation, vol. 107, (no. 10), pp. 1311-1318, 2001.
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