425 Publications (Page 4 of 17)
2014
Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation
Srinivasan, MythilySrinivasan, MythilyBlackburn, CorrineBlackburn, CorinneLahiri, Debomoy K and Lahiri, Debomoy K
Drug design, development and therapy, vol. 8, pp. 2421, 2014-00-00. | Journal Article
 
Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research.
Ray, BalmikiChopra, NipunLong, Justin M and Lahiri, Debomoy K
Molecular brain, vol. 7, pp. 63, September 16, 2014. | Journal Article
 
Impact of acamprosate on plasma amyloid-β precursor protein in youth: A pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker
Erickson, CraigErickson, CraigErickson, Craig ARay, BalmikiRay, BalmikiRay, BalmikiMaloney, BryanMaloney, BryanMaloney, BryanWink, Logan KWink, LoganWink, LoganBowers, KatherineBowers, KatherineBowers, KatherineSchaefer, ToriSchaefer, Tori LSchaefer, ToriMcDougle, ChristopherMcDougle, ChristopherMcDougle, Christopher JSokol, DeborahSokol, DeborahSokol, Deborah KLahiri, DebomoyLahiri, Debomoy and Lahiri, Debomoy K
Journal of Psychiatric Research, vol. 59, pp. 228, 2014. | Journal Article
 
Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.
Greig, Nigel HTweedie, DavidRachmany, LitalLi, YazhouRubovitch, VarditSchreiber, ShaulChiang, Yung-HsiaoHoffer, Barry JMiller, JonathanLahiri, Debomoy KSambamurti, KumarBecker, Robert E and Pick, Chaim G
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol. 10, (no. 1 Suppl), pp. S62-75, 2014/Feb. | Journal Article
 
Intravenous immunoglobulin (IVIG) treatment exerts antioxidant and neuropreservatory effects in preclinical models of Alzheimer's disease
Counts, Scott ERay, BalmikiMufson, Elliott JPerez, Sylvia EHe, Bin and Lahiri, Debomoy K
Journal of clinical immunology, vol. 34 Suppl 1, (no. 1), pp. S85, 2014-Jul. | Journal Article
 
Intravenous immunoglobulin treatment preserves and protects primary rat hippocampal neurons and primary human brain cultures against oxidative insults.
Lahiri, Debomoy K and Ray, Balmiki
Current Alzheimer research, vol. 11, (no. 7), pp. 645-654, 2014. | Journal Article
 
K114 inhibits A-beta aggregation and inflammation in vitro and in vivo in AD/Tg mice.
Zhang, Yi-HongMann, DushyantRaymick, JamesSarkar, SumitPaule, Merle GLahiri, Debomoy KDumas, MelanieBell-Cohen, Ashlee and Schmued, Larry C
Current Alzheimer research, vol. 11, (no. 3), pp. 299-308, 2014/Mar. | Journal Article
 
Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.
Perez, Felipe PPerez, Felipe PBose, DavidBose, DavidMaloney, BryanMaloney, BryanNho, KwangsikNho, KwangsikShah, KavitaShah, KavitaLahiri, Debomoy K and Lahiri, Debomoy K
Journal of Alzheimer's disease : JAD, vol. 40, (no. 1), pp. 1-17, 2014. | Journal Article
 
Lessons from a BACE1 inhibitor trial: off-site but not off base.
Lahiri, Debomoy KMaloney, BryanLong, Justin M and Greig, Nigel H
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol. 10, (no. 5 Suppl), pp. S411-S419, October 2014. | Journal Article
 
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects.
Long, Justin MRay, Balmiki and Lahiri, Debomoy K
The Journal of biological chemistry, vol. 289, (no. 8), pp. 5184-98, 2014/Feb/21. | Journal Article
 
MICRORNA-339-5P IS DYSREGULATED IN ALZHEIMER'S DISEASE AND IS INVERSELY PROPORTIONAL TO BACE1 EXPRESSION: IMPLICATION IN TESTING NOVEL DRUG TARGETS
Lahiri, Debomoy and Long, Justin
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P868, 2014. | Journal Article
 
NEUROPRESERVATIVE AND NEUROPROTECTIVE ROLE OF IVIG PREPARATION
Lahiri, Debomoy and Ray, Balmiki
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P779, 2014. | Journal Article
 
Overview of Immunotherapy in Alzheimer’s Disease (AD) and Mechanisms of IVIG Neuroprotection in Preclinical Models of AD
Counts, Scott E and Lahiri, Debomoy K
Current Alzheimer research, vol. 11, (no. 7), pp. 625, 2014-01-01. | Journal Article
 
Role of early life exposure and environment on neurodegeneration: implications on brain disorders.
Modgil, ShwetaLahiri, Debomoy KSharma, Vijay L and Anand, Akshay
Translational neurodegeneration, vol. 3, pp. 9, 2014. | Journal Article
 
Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-β Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimerµs Disease Subjects: Exploring the Cholinergic Anti-inflammatory Pathway
Reale, MarcellaNicola, MartaVelluto, LuciaD'Angelo, ChiaraCostantini, EricaLahiri, DebomoyKamal, MohammadYu, Qian-sheng and Greig, Nigel
Current Alzheimer Research, vol. 11, (no. 6), pp. 622, 2014-July. | Journal Article
 
Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-β Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimer’s Disease Subjects: Exploring the Cholinergic Anti-inflammatory Pathway
Reale, MarcellaNicola, MartaVelluto, LuciaD’Angelo, ChiaraCostantini, EricaLahiri, DebomoyKamal, MohammadYu, Qian-sheng and Greig, Nigel
Current Alzheimer Research, vol. 11, (no. 6), pp. 622, 2014-07-31. | Journal Article
 
TREATMENT WITH SP1 INHIBITING DRUGS MODULATES APP AND BACE1 LEVELS IN HUMAN CELLS: IMPLICATION IN TESTING A NOVEL TARGET FOR ALZHEIMER'S DISEASE
Bayon, Baindu and Lahiri, Debomoy
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P327, 2014. | Journal Article
2013
Abnormal cerebrospinal fluid (CSF) dynamics in Alzheimer's disease and normal pressure hydrocephalus: CSF-amyloid beta precursor protein metabolites as possible biomarkers
Lahiri, Debomoy K and Ray, B.
European Journal of Neurology, vol. 20, (no. 2), pp. 211-213, 2013. | Journal Article
 
Abnormal cerebrospinal fluid (CSF) dynamics in Alzheimer's disease and normal pressure hydrocephalus: CSF-amyloid β precursor protein metabolites as possible biomarkers.
Lahiri, Debomoy K and Ray, B
European journal of neurology : the official journal of the European Federation of Neurological Societies, vol. 20, (no. 2), pp. 211-3, 2013/Feb. | Journal Article
 
Alcohol drinking and deprivation alter basal extracellular glutamate concentrations and clearance in the mesolimbic system of alcohol‐preferring (P) rats
Ding, Zheng MingDing, Zheng‐MingRodd, Zachary ARodd, Zachary AEngleman, Eric AEngleman, Eric ABailey, Jason ABailey, Jason ALahiri, Debomoy KLahiri, Debomoy KMcBride, William J and Mc Bride, William J
Addiction Biology, vol. 18, (no. 2), pp. 306, March 2013. | Journal Article
 
A specific microRNA (miR-339-5p) is reduced in Alzheimer's disease brain and able to lower BACE1 and BETA-AMYLOID peptide levels in human fetal brain cultures, suggesting a novel drug target for ALZHEIMER'S
Lahiri, DebomoyLong, Justin and Ray, Balmiki
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 8, (no. 4), pp. S769, 2013. | Journal Article
 
Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway.
Lahiri, Debomoy KSokol, Deborah KErickson, CraigRay, BalmikiHo, Chang Y and Maloney, Bryan
Frontiers in cellular neuroscience, vol. 7, pp. 94, 2013. | Journal Article
 
BACE1 gene regulation: A novel drug target in Alzheimer's disease
Bayon, BainduLahiri, Debomoy and Bailey, Jason
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 9, (no. 4), pp. P304, 2013. | Journal Article
 
Current Alzheimer Research: Editorial [Progress of “Current Alzheimer Research” and Future Direction]
Lahiri, Debomoy
Current Alzheimer Research, vol. 10, (no. 1), pp. 3, 2013-January. | Journal Article
 
Effect of IVIg in preserving human primary neurons and protecting them against oxidative stress
Lahiri, Debomoy and Ray, Balmiki
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 9, (no. 4), pp. P800, 2013. | Journal Article