425 Publications (Page 4 of 17)
2014
Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammationSrinivasan, Mythily⋅Srinivasan, Mythily⋅Blackburn, Corrine⋅Blackburn, Corinne⋅Lahiri, Debomoy K and Lahiri, Debomoy KDrug design, development and therapy, vol. 8, pp. 2421, 2014-00-00.
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Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research.Ray, Balmiki⋅Chopra, Nipun⋅Long, Justin M and Lahiri, Debomoy KMolecular brain, vol. 7, pp. 63, September 16, 2014.
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Impact of acamprosate on plasma amyloid-β precursor protein in youth: A pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein markerErickson, Craig⋅Erickson, Craig⋅Erickson, Craig A⋅Ray, Balmiki⋅Ray, Balmiki⋅Ray, Balmiki⋅Maloney, Bryan⋅Maloney, Bryan⋅Maloney, Bryan⋅Wink, Logan K⋅Wink, Logan⋅Wink, Logan⋅Bowers, Katherine⋅Bowers, Katherine⋅Bowers, Katherine⋅Schaefer, Tori⋅Schaefer, Tori L⋅Schaefer, Tori⋅McDougle, Christopher⋅McDougle, Christopher⋅McDougle, Christopher J⋅Sokol, Deborah⋅Sokol, Deborah⋅Sokol, Deborah K⋅Lahiri, Debomoy⋅Lahiri, Debomoy and Lahiri, Debomoy KJournal of Psychiatric Research, vol. 59, pp. 228, 2014.
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Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.Greig, Nigel H⋅Tweedie, David⋅Rachmany, Lital⋅Li, Yazhou⋅Rubovitch, Vardit⋅Schreiber, Shaul⋅Chiang, Yung-Hsiao⋅Hoffer, Barry J⋅Miller, Jonathan⋅Lahiri, Debomoy K⋅Sambamurti, Kumar⋅Becker, Robert E and Pick, Chaim GAlzheimer's & dementia : the journal of the Alzheimer's Association, vol. 10, (no. 1 Suppl), pp. S62-75, 2014/Feb.
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Intravenous immunoglobulin (IVIG) treatment exerts antioxidant and neuropreservatory effects in preclinical models of Alzheimer's diseaseCounts, Scott E⋅Ray, Balmiki⋅Mufson, Elliott J⋅Perez, Sylvia E⋅He, Bin and Lahiri, Debomoy KJournal of clinical immunology, vol. 34 Suppl 1, (no. 1), pp. S85, 2014-Jul.
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Intravenous immunoglobulin treatment preserves and protects primary rat hippocampal neurons and primary human brain cultures against oxidative insults.Lahiri, Debomoy K and Ray, BalmikiCurrent Alzheimer research, vol. 11, (no. 7), pp. 645-654, 2014.
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K114 inhibits A-beta aggregation and inflammation in vitro and in vivo in AD/Tg mice.Zhang, Yi-Hong⋅Mann, Dushyant⋅Raymick, James⋅Sarkar, Sumit⋅Paule, Merle G⋅Lahiri, Debomoy K⋅Dumas, Melanie⋅Bell-Cohen, Ashlee and Schmued, Larry CCurrent Alzheimer research, vol. 11, (no. 3), pp. 299-308, 2014/Mar.
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Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.Perez, Felipe P⋅Perez, Felipe P⋅Bose, David⋅Bose, David⋅Maloney, Bryan⋅Maloney, Bryan⋅Nho, Kwangsik⋅Nho, Kwangsik⋅Shah, Kavita⋅Shah, Kavita⋅Lahiri, Debomoy K and Lahiri, Debomoy KJournal of Alzheimer's disease : JAD, vol. 40, (no. 1), pp. 1-17, 2014.
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Lessons from a BACE1 inhibitor trial: off-site but not off base.Lahiri, Debomoy K⋅Maloney, Bryan⋅Long, Justin M and Greig, Nigel HAlzheimer's & dementia : the journal of the Alzheimer's Association, vol. 10, (no. 5 Suppl), pp. S411-S419, October 2014.
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MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects.Long, Justin M⋅Ray, Balmiki and Lahiri, Debomoy KThe Journal of biological chemistry, vol. 289, (no. 8), pp. 5184-98, 2014/Feb/21.
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MICRORNA-339-5P IS DYSREGULATED IN ALZHEIMER'S DISEASE AND IS INVERSELY PROPORTIONAL TO BACE1 EXPRESSION: IMPLICATION IN TESTING NOVEL DRUG TARGETSLahiri, Debomoy and Long, JustinAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P868, 2014.
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NEUROPRESERVATIVE AND NEUROPROTECTIVE ROLE OF IVIG PREPARATIONLahiri, Debomoy and Ray, BalmikiAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P779, 2014.
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Overview of Immunotherapy in Alzheimer’s Disease (AD) and Mechanisms of IVIG Neuroprotection in Preclinical Models of ADCounts, Scott E and Lahiri, Debomoy KCurrent Alzheimer research, vol. 11, (no. 7), pp. 625, 2014-01-01.
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Role of early life exposure and environment on neurodegeneration: implications on brain disorders.Modgil, Shweta⋅Lahiri, Debomoy K⋅Sharma, Vijay L and Anand, AkshayTranslational neurodegeneration, vol. 3, pp. 9, 2014.
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Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-β Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimerµs Disease Subjects: Exploring the Cholinergic Anti-inflammatory PathwayReale, Marcella⋅Nicola, Marta⋅Velluto, Lucia⋅D'Angelo, Chiara⋅Costantini, Erica⋅Lahiri, Debomoy⋅Kamal, Mohammad⋅Yu, Qian-sheng and Greig, NigelCurrent Alzheimer Research, vol. 11, (no. 6), pp. 622, 2014-July.
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Selective Acetyl- and Butyrylcholinesterase Inhibitors Reduce Amyloid-β Ex Vivo Activation of Peripheral Chemo-cytokines From Alzheimer’s Disease Subjects: Exploring the Cholinergic Anti-inflammatory PathwayReale, Marcella⋅Nicola, Marta⋅Velluto, Lucia⋅D’Angelo, Chiara⋅Costantini, Erica⋅Lahiri, Debomoy⋅Kamal, Mohammad⋅Yu, Qian-sheng and Greig, NigelCurrent Alzheimer Research, vol. 11, (no. 6), pp. 622, 2014-07-31.
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TREATMENT WITH SP1 INHIBITING DRUGS MODULATES APP AND BACE1 LEVELS IN HUMAN CELLS: IMPLICATION IN TESTING A NOVEL TARGET FOR ALZHEIMER'S DISEASEBayon, Baindu and Lahiri, DebomoyAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 10, (no. 4), pp. P327, 2014.
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2013
Abnormal cerebrospinal fluid (CSF) dynamics in Alzheimer's disease and normal pressure hydrocephalus: CSF-amyloid beta precursor protein metabolites as possible biomarkersLahiri, Debomoy K and Ray, B.European Journal of Neurology, vol. 20, (no. 2), pp. 211-213, 2013.
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Abnormal cerebrospinal fluid (CSF) dynamics in Alzheimer's disease and normal pressure hydrocephalus: CSF-amyloid β precursor protein metabolites as possible biomarkers.Lahiri, Debomoy K and Ray, BEuropean journal of neurology : the official journal of the European Federation of Neurological Societies, vol. 20, (no. 2), pp. 211-3, 2013/Feb.
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Alcohol drinking and deprivation alter basal extracellular glutamate concentrations and clearance in the mesolimbic system of alcohol‐preferring (P) ratsDing, Zheng Ming⋅Ding, Zheng‐Ming⋅Rodd, Zachary A⋅Rodd, Zachary A⋅Engleman, Eric A⋅Engleman, Eric A⋅Bailey, Jason A⋅Bailey, Jason A⋅Lahiri, Debomoy K⋅Lahiri, Debomoy K⋅McBride, William J and Mc Bride, William JAddiction Biology, vol. 18, (no. 2), pp. 306, March 2013.
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A specific microRNA (miR-339-5p) is reduced in Alzheimer's disease brain and able to lower BACE1 and BETA-AMYLOID peptide levels in human fetal brain cultures, suggesting a novel drug target for ALZHEIMER'SLahiri, Debomoy⋅Long, Justin and Ray, BalmikiAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 8, (no. 4), pp. S769, 2013.
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Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway.Lahiri, Debomoy K⋅Sokol, Deborah K⋅Erickson, Craig⋅Ray, Balmiki⋅Ho, Chang Y and Maloney, BryanFrontiers in cellular neuroscience, vol. 7, pp. 94, 2013.
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BACE1 gene regulation: A novel drug target in Alzheimer's diseaseBayon, Baindu⋅Lahiri, Debomoy and Bailey, JasonAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 9, (no. 4), pp. P304, 2013.
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Current Alzheimer Research: Editorial [Progress of “Current Alzheimer Research” and Future Direction]Lahiri, DebomoyCurrent Alzheimer Research, vol. 10, (no. 1), pp. 3, 2013-January.
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Effect of IVIg in preserving human primary neurons and protecting them against oxidative stressLahiri, Debomoy and Ray, BalmikiAlzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 9, (no. 4), pp. P800, 2013.
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