My work balances teaching and research on the neurobiology and genetics of aging and Alzheimer’s disease (AD).
My main research interest is to understand how degeneration of brain cells under laboratory conditions can be more closely made to resemble the “natural” neurodegeneration of AD.
My primary focus is to understand the mechanisms of aging and longevity of the brain; origin and biogenesis of AD-associated amyloid plaque; and gene regulation related to AD and other neuropsychiatric disorders.
My clinical interests are translational, collaborative and limited to using well-characterized human samples (plasma, CSF and brain tissues).