Expertise

My work balances teaching and research on the neurobiology and genetics of aging and Alzheimer’s disease (AD). 

My main research interest is to understand how degeneration of brain cells under laboratory conditions can be more closely made to resemble the “natural” neurodegeneration of AD.

My primary focus is to understand the mechanisms of aging and longevity of the brain; origin and biogenesis of AD-associated amyloid plaque; and gene regulation related to AD and other neuropsychiatric disorders.

My clinical interests are translational, collaborative and limited to using well-characterized human samples (plasma, CSF and brain tissues).

Past Affiliations

Professor, Stark Neurosciences Research Institute, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Assistant Professor, Department of Psychiatry, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Professor, Department of Medical and Molecular Genetics, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Professor, Institute of Psychiatric Research, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Associate Professor, Institute of Psychiatric Research, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Department of Medicine, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Communities
Human Genetics, Psychiatry, Psychiatry, Neuroscience, Biomedical Science
Degrees
PhD, Banaras Hindu University, Biochemistry, 1980
MSc, Banaras Hindu University, Biochemistry, 1975
BSc, Banaras Hindu University, Chemistry, 1973
Keywords
asia, southern biotechnology depression alzheimer's disease antisera gene cloning enzymes gene expression cell lines geriatrics & gerontology cell & developmental biology biochemistry & molecular biology atomic and molecular structure biochemistry, nucleic acids biochemistry, proteins