425 Publications (Page 15 of 17)
2003
Thiothalidomides: novel isosteric analogues of thalidomide with enhanced TNF-alpha inhibitory activity.
Zhu, Xiaoxiang⋅Giordano, Tony⋅Yu, Qian-Sheng⋅Holloway, Harold W⋅Perry, Tracy A⋅Lahiri, Debomoy K⋅Brossi, Arnold and Greig, Nigel H
Journal of medicinal chemistry, vol. 46, (no. 24), pp. 5222-9, 2003/Nov/20. | Journal Article
2002
Advances in the Cellular and Molecular Biology of the Beta-Amyloid Protein in Alzheimer's Disease
Sambamurti, Kumar⋅Greig, Nigel H and Lahiri, Debomoy K
Neuromolecular Medicine, vol. 1, (no. 1), pp. 1-31, 2002. | Journal Article
 
Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region.
Rogers, Jack T⋅Randall, Jeffrey D⋅Eder, Paul S⋅Huang, Xudong⋅Bush, Ashley⋅Tanzi, Rudy E⋅Venti, Amanda⋅Payton, Sandra M⋅Giordano, Tony⋅Nagano, Seiichi⋅Cahill, Catherine M⋅Moir, Robert⋅Lahiri, Debomoy K⋅Greig, Nigel H⋅Sarang, Satinder S and Gullans, Steven R
Journal of molecular neuroscience : MN, vol. 19, (no. 1-2), pp. 77-82, 2002 Aug-Oct. | Journal Article
 
An Iron-responsive Element Type II in the 5'-Untranslated Region of the Alzheimer's Amyloid Precursor Protein Transcript
Rogers, Jack T⋅Randall, JD⋅Cahill, CM⋅Eder, PS⋅Huang, Xudong⋅Gunshin, H.⋅Leiter, L.⋅McPhee, J.⋅Sarang, SS⋅Utsuki, T.⋅Greig, Nigel H⋅Lahiri, Debomoy K⋅Tanzi, Rudy E⋅Bush, Ashley⋅Giordano, Tony and Gullans, Steven R
Journal of Biological Chemistry, vol. 277, (no. 47), pp. 45518-45528, 2002. | Journal Article
 
A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells.
Perry, TracyAnn⋅Lahiri, Debomoy K⋅Chen, Demao⋅Zhou, Jie⋅Shaw, Karen T⋅Egan, Josephine M and Greig, Nigel H
The Journal of pharmacology and experimental therapeutics, vol. 300, (no. 3), pp. 958-66, 2002/Mar. | Journal Article
 
Butyrylcholinesterase: an important new target in Alzheimer's disease therapy.
Greig, Nigel H⋅Lahiri, Debomoy K and Sambamurti, Kumar
International psychogeriatrics / IPA, vol. 14 Suppl 1, pp. 77-91, 2002. | Journal Article
 
Current drug targets for Alzheimer's disease treatment
Lahiri, Debomoy K⋅Lahiri, Debomoy K⋅Farlow, Martin R⋅Farlow, Martin R⋅Greig, Nigel H⋅Greig, Nigel H⋅Sambamurti, Kumar and Sambamurti, Kumar
Drug Development Research, vol. 56, (no. 3), pp. 281, July 2002. | Journal Article
 
Developmental expression of the beta-amyloid precursor protein and heat-shock protein 70 in the cerebral hemisphere region of the rat brain.
Lahiri, Debomoy K⋅Nall, C⋅Chen, D⋅Zaphiriou, M⋅Morgan, C and Nurnberger, J I
Annals of the New York Academy of Sciences. , vol. 965, pp. 324-33, 2002/Jun. | Journal Article
 
Dietary modulation of age-related changes in cerebral pro-oxidant status
Bondy, Stephen C⋅Yang, YE⋅Walsh, TJ⋅Gie, Y-W and Lahiri, Debomoy K
Neurochemistry International, vol. 40, (no. 2), pp. 123-130, 2002. | Journal Article
 
Functional characterization of the 5'-regulatory region of the murine apolipoprotein gene.
Lahiri, Debomoy K⋅Alley, G M⋅Ge, Y-W and Du, Y
Annals of the New York Academy of Sciences. , vol. 973, pp. 340-4, 2002/Nov. | Journal Article
 
Nicotine lowers the secretion of the Alzheimer's amyloid beta -protein precursor that contains amyloid beta -peptide in rat
Utsuki, T.⋅Shoaib, M.⋅Holloway, HW⋅Ingram, Donald K⋅Wallace, WC⋅Haroutunian, V.⋅Sambamurti, Kumar⋅Lahiri, Debomoy K and Greig, Nigel H
Journal of Alzheimer's Disease, vol. 4, (no. 5), pp. 405-415, 2002. | Journal Article
 
Nicotine lowers the secretion of the Alzheimer's amyloid β-protein precursor that contains amyloid β-peptide in rat
Utsuki, Tadanobu⋅Shoaib, Mohammed⋅Holloway, Harold W⋅Ingram, Donald K⋅Wallace, William C⋅Haroutunian, Vahram⋅Sambamurti, Kumar⋅Lahiri, Debomoy K and Greig, Nigel H
Journal of Alzheimer's disease : JAD, vol. 4, (no. 5), pp. 415, 2002-Oct. | Journal Article
 
Nicotine reduces the secretion of Alzheimer's beta-amyloid precursor protein containing beta-amyloid peptide in the rat without altering synaptic proteins.
Lahiri, Debomoy K⋅Utsuki, T⋅Chen, D⋅Farlow, M R⋅Shoaib, M⋅Ingram, D K and Greig, N H
Annals of the New York Academy of Sciences. , vol. 965, pp. 364-72, 2002/Jun. | Journal Article
 
Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.
Zhu, Xiaoxiang⋅Yu, Qian-Sheng⋅Cutler, Roy G⋅Culmsee, Carsten⋅Holloway, Harold W⋅Lahiri, Debomoy K⋅Mattson, Mark P and Greig, Nigel H
Journal of medicinal chemistry, vol. 45, (no. 23), pp. 5090-7, 2002/Nov/7. | Journal Article
 
Potential Intervention by Vaccinia Virus Complement Control Protein of the Signals Contributing to the Progression of Central Nervous System Injury to Alzheimer's Disease
KOTWAL, GIRISH J⋅Lahiri, Debomoy K and HICKS, RAMONA
Annals of the New York Academy of Sciences, vol. 973, (no. 1), pp. 322, November 2002. | Journal Article
 
Targeting APP metabolism for the treatment of Alzheimer's disease
Sambamurti, Kumar⋅Hardy, John⋅Refolo, Lorenzo M and Lahiri, Debomoy K
Drug Development Research, vol. 56, (no. 2), pp. 227, June 2002. | Journal Article
 
The role of the carboxyl-terminal fragments of amyloid precursor protein in Alzheimer's disease.
Lahiri, Debomoy K⋅Kotwal, G J⋅Farlow, M R⋅Sima, Anders A⋅Kupsky, W⋅Sarkar, F H and Sambamurti, K
Annals of the New York Academy of Sciences. , vol. 973, pp. 334-9, 2002/Nov. | Journal Article
2001
A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase.
Greig, Nigel H⋅Utsuki, T⋅Yu, Q⋅Zhu, X⋅Holloway, H W⋅Perry, T⋅Lee, B⋅Ingram, Donald K and Lahiri, Debomoy K
Current medical research and opinion, vol. 17, (no. 3), pp. 159-65, 2001. | Journal Article
 
Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
Shaw, KTY⋅Utsuki, T.⋅Rogers, J.⋅Yu, Q.⋅Sambamurti, Kumar⋅Brossi, A.⋅Ge, Y.⋅Lahiri, Debomoy K and Greig, Nigel H
Proceedings of the National Academy of Sciences, USA, vol. 98, (no. 13), pp. 7605-7610, 2001. | Journal Article
2000
Analysis of the 5'-flanking region of the beta -amyloid precursor protein gene that contributes to increased promoter activity in differentiated neuronal cells
Lahiri, Debomoy K⋅Song, Weihong and Ge, YW
Molecular Brain Research, vol. 77, (no. 2), pp. 185-198, 2000. | Journal Article
 
Cholinesterase inhibitors, beta-amyloid precursor protein and amyloid beta-peptides in Alzheimer's disease.
Lahiri, Debomoy K⋅Farlow, M R⋅Hintz, N⋅Utsuki, T and Greig, N H
Acta Neurologica Scandinavica. Supplementum, vol. 176, pp. 60-7, 2000. | Journal Article
 
Effect of a memory-enhancing drug, AIT-082, on the level of synaptophysin.
Lahiri, Debomoy K⋅Ge, Y W and Farlow, Martin R
Annals of the New York Academy of Sciences. , vol. 903, pp. 387-93, 2000/Apr. | Journal Article
 
Efficient DNA transfection in neuronal and astrocytic cell lines
Ghosh, Chandramallika⋅Song, Weihong and Lahiri, Debomoy
Molecular Biology Reports, vol. 27, (no. 2), pp. 121, 20000600. | Journal Article
 
Electrophoretic mobility shift assay for the detection of specific DNA-protein complex in nuclear extracts from the cultured cells and frozen autopsy human brain tissue.
Lahiri, Debomoy K and Ge, Y
Brain research. Brain research protocols. , vol. 5, (no. 3), pp. 257-65, 2000/Jul. | Journal Article
 
Increased secretion of the β-amyloid precursor protein in PC12 cells treated with a memory-enhancing drug AIT-082
Lahiri, Debomoy K⋅Glasky, Michelle S and Farlow, Martin R
Neurobiology of Aging, vol. 21, pp. 274, 2000. | Journal Article