The Brutkiewicz laboratory studies immune evasion by viruses and tumors, the regulation of antigen presentation by various signal transduction pathways, and the role of innate and adaptive immune responses in CNS injuries and disorders.
Ongoing studies are analyzing additional mechanisms by which some tumors can evade this arm of the host's innate antitumor defenses, including those signal transduction pathways that play an important role in such activity.
Dr. Brutkiewicz's research interests include:
- How blood cancer cells can evade recognition by the host's immune system, with the ultimate goal to identify new targets for effective antitumor therapy.
Expertise: Spinal Cord and Brain Injury Research