59 Publications (Page 1 of 3)
2023
Generating high-fidelity cochlear organoids from human pluripotent stem cells.
Moore, Stephen TMoore, Stephen TMoore, Stephen T.Nakamura, TakashiNakamura, TakashiNakamura, TakashiNie, JingNie, JingNie, JingSolivais, Alexander JSolivais, Alexander J.Solivais, Alexander JAristizábal-Ramírez, IsabelAristizábal-Ramírez, IsabelAristizábal-Ramı́rez, IsabelUeda, YoshitomoUeda, YoshitomoUeda, YoshitomoManikandan, MayakannanManikandan, MayakannanManikandan, MayakannanReddy, V ShwetaReddy, V. ShwetaReddy, V ShwetaRomano, Daniel RRomano, Daniel R.Romano, Daniel RHoffman, John RHoffman, John R.Hoffman, John RPerrin, Benjamin J.Perrin, Benjamin JPerrin, Benjamin JNelson, Rick FNelson, Rick F.Nelson, Rick FFrolenkov, Gregory IFrolenkov, Gregory IFrolenkov, Gregory I.Chuva de Sousa Lopes, Susana MSousa Lopes, Susana M. ChuvaChuva de Sousa Lopes, Susana MHashino, EriHashino, Eri and Hashino, Eri
Cell stem cell, vol. 30, (no. 7), pp. 950-961.e7, July 6, 2023. | Journal Article
2021
Deafness-in-a-dish: modeling hereditary deafness with inner ear organoids.
Romano, Daniel RHashino, Eri and Nelson, Rick F
Human genetics, August 3, 2021. | Journal Article
 
Directed Differentiation of Human Pluripotent Stem Cells into Inner Ear Organoids.
Ueda, YoshitomoMoore, Stephen T and Hashino, Eri
Methods in molecular biology (Clifton, N.J.), November 2, 2021. | Journal Article
2020
Generation of inner ear organoids from human pluripotent stem cells.
Nie, JingNie, JingHashino, Eri and Hashino, Eri
Methods in cell biology, vol. 159, pp. 303-321, 2020. | Journal Article
 
Progress in Modeling and Targeting Inner Ear Disorders with Pluripotent Stem Cells.
Tang, Pei-CiaoHashino, Eri and Nelson, Rick F
Stem cell reports, May 6, 2020. | Journal Article
2019
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids
Tang, Pei-CiaoTang, Pei CiaoTang, Pei-CiaoAlex, Alpha LAlex, Alpha LAlex, Alpha LNie, JingNie, JingNie, JingLee, JiyoonLee, JiyoonLee, JiyoonRoth, Adam ARoth, Adam ARoth, Adam ABooth, Kevin TBooth, Kevin TBooth, Kevin TKoehler, Karl RKoehler, Karl RKoehler, Karl RHashino, EriHashino, EriHashino, EriNelson, Rick FNelson, Rick F and Nelson, Rick F
Stem Cell Reports, vol. 13, (no. 1), pp. 162, 2019-07-09. | Journal Article
2018
The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex
Patel, DharmeshkumarPatel, DharmeshkumarShimomura, AtsushiShimomura, AtsushiMajumdar, SreeparnaMajumdar, SreeparnaHolley, Matthew CHolley, Matthew CHashino, Eri and Hashino, Eri
PLoS One, vol. 13, (no. 1), Jan 2018. | Journal Article
2017
Directed Differentiation of Mouse Embryonic Stem Cells Into Inner Ear Sensory Epithelia in 3D Culture.
Nie, JingNie, JingKoehler, Karl RKoehler, Karl RHashino, Eri and Hashino, Eri
Methods in molecular biology (Clifton, N.J.), vol. 1597, pp. 67-83, 2017. | Journal Article
 
Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells
Koehler, KarlKoehler, Karl RKoehler, Karl RKoehler, Karl RNie, JingNie, JingNie, JingLongworth-Mills, EmmaLongworth-mills, EmmaLongworth-Mills, EmmaLongworth-Mills, EmmaLiu, Xiao-PingLiu, Xiao-PingLiu, Xiao-PingLiu, Xiao-pingLee, JiyoonLee, JiyoonLee, JiyoonLee, JiyoonHolt, JeffreyHolt, Jeffrey RHolt, Jeffrey RHolt, Jeffrey RHashino, EriHashino, Eri and Hashino, Eri
Nature Biotechnology, vol. 35, (no. 6), pp. 583-589, Jun 2017. | Journal Article
 
Organoid technologies meet genome engineering.
Nie, JingNie, JingHashino, Eri and Hashino, Eri
EMBO reports, February 15, 2017. | Journal Article
2016
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.
Liu, Xiao-PingKoehler, Karl RMikosz, Andrew MHashino, Eri and Holt, Jeffrey R
Nature communications, vol. 7, pp. 11508, May 24, 2016. | Journal Article
 
Generating Inner Ear Organoids from Mouse Embryonic Stem Cells.
Longworth-Mills, EmmaKoehler, Karl R and Hashino, Eri
Methods in molecular biology (Clifton, N.J.), vol. 1341, pp. 391-406, 2016. | Journal Article
 
Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture.
DeJonge, Rachel EDeJonge, Rachel ELiu, Xiao-PingLiu, Xiao-PingDeig, Christopher RDeig, Christopher RHeller, StefanHeller, StefanKoehler, Karl RKoehler, Karl RHashino, Eri and Hashino, Eri
PloS one, vol. 11, (no. 9), pp. e0162508. | Journal Article
2015
Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP.
Shimomura, AtsushiPatel, DharmeshkumarWilson, Sarah MKoehler, Karl RKhanna, Rajesh and Hashino, Eri
PloS one, vol. 10, (no. 8), pp. e0135060, 2015. | Journal Article
2014
3D mouse embryonic stem cell culture for generating inner ear organoids.
Koehler, Karl RKoehler, Karl RHashino, Eri and Hashino, Eri
Nature protocols, vol. 9, (no. 6), pp. 1229-1244, 2014. | Journal Article
2013
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture.
Koehler, Karl RKoehler, Karl RMikosz, Andrew MMikosz, Andrew MMolosh, Andrei IMolosh, Andrei IPatel, DharmeshkumarPatel, DharmeshkumarHashino, Eri and Hashino, Eri
Nature, vol. 500, (no. 7461), pp. 217-221, August 8, 2013. | Journal Article
 
Retinoic acid deficiency impairs the vestibular function.
Romand, RaymondKrezel, WojciechBeraneck, MathieuCammas, LauraFraulob, ValérieMessaddeq, NadiaKessler, PascalHashino, Eri and Dollé, Pascal
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 33, (no. 13), pp. 5856-66, 2013/Mar/27. | Journal Article
2012
Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes.
Krishnan, SubhaKrishnan, SubhaMali, Raghuveer SinghMali, Raghuveer SinghKoehler, Karl RKoehler, Karl RVemula, SasidharVemula, SasidharChatterjee, AnindyaChatterjee, AnindyaGhosh, JoydeepGhosh, JoydeepRamdas, BaskarRamdas, BaskarMa, PeilinMa, PeilinHashino, EriHashino, EriKapur, Reuben and Kapur, Reuben
PloS one, vol. 7, (no. 1), pp. e28979, 2012. | Journal Article
 
Class IA PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes
Krishnan, SubhaKoehler, KarlVemula, SasidharChatterjee, AnindyaGhosh, JoydeepMa, PeilinHashino, Eri and Kapur, Reuben
PLoS One, vol. 7, (no. 1), Jan 2012. | Journal Article
 
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53.
Vemula, SasidharVemula, SasidharVemula, SasidharShi, JianjianShi, JianjianShi, JianjianMali, Raghuveer SinghMali, Raghuveer SinghMali, Raghuveer SinghMa, PeilinMa, PeilinMa, PeilinLiu, YanLiu, YanLiu, YanHanneman, PhilipHanneman, PhilipHanneman, PhilipKoehler, Karl RKoehler, Karl RKoehler, Karl RHashino, EriHashino, EriHashino, EriWei, LeiWei, LeiWei, LeiKapur, ReubenKapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 14), pp. 2868-2878, October 4, 2012. | Journal Article
2011
Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
Ma, PeilinMa, PeilinVemula, SasidharVemula, SasidharMunugalavadla, VeerendraMunugalavadla, VeerendraChen, JinbiaoChen, JinbiaoSims, EmilySims, EmilyBorneo, JovencioBorneo, JovencioKondo, TakakoKondo, TakakoRamdas, BaskarRamdas, BaskarMali, RaghuveerMali, Raghuveer SLi, ShuoLi, ShuoHashino, EriHashino, EriTakemoto, CliffordTakemoto, CliffordKapur, Reuben and Kapur, Reuben
Molecular and cellular biology, vol. 31, (no. 19), pp. 4052-62, 2011/Oct. | Journal Article
 
Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells.
Koehler, Karl RTropel, PhilippeTheile, Jonathan WKondo, TakakoCummins, Theodore RViville, Stéphane and Hashino, Eri
BMC neuroscience, vol. 12, pp. 82, 2011. | Journal Article
 
Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3.
Kondo, TakakoMatsuoka, Akihiro JShimomura, AtsushiKoehler, Karl RChan, Rebecca JMiller, Josef MSrour, Edward F and Hashino, Eri
Stem cells (Dayton, Ohio), vol. 29, (no. 5), pp. 836-46, 2011/May. | Journal Article
2010
In‐vivo assessment of migration and engraftment of stem cells in the cochlea using a high‐resolution microscopic‐endoscope
Matsuoka, Akihiro JMatsuoka, Akihiro JFritsch, Michael HFritsch, Michael HKoehler, Karl RKoehler, Karl RHashino, Eri and Hashino, Eri
The Laryngoscope, vol. 120, (no. S4), pp. S212, 2010. | Journal Article
 
Magnetic Resonance Imaging of Stem Cells in the Cochlea
Fritsch, MichaelMatsuoka, Akihiro and Hashino, Eri
Otolaryngology - Head and Neck Surgery, vol. 143, (no. 2), pp. P98, 2010. | Journal Article