19 Publications
2009
Human carboxylesterases: an update on CES1, CES2 and CES3.
Sanghani, Sonal P⋅Sanghani, Paresh C⋅Schiel, Marissa A and Bosron, William F
Protein and peptide letters, vol. 16, (no. 10), pp. 1207-14, 2009. | Journal Article
2008
Expression of carboxylesterase and lipase genes in rat liver cell-types.
Mello, Tommaso⋅Nakatsuka, Alice⋅Fears, Sharry⋅Davis, Wilhelmina⋅Tsukamoto, Hidekazu⋅Bosron, William F and Sanghani, Sonal P
Biochemical and biophysical research communications, vol. 374, (no. 3), pp. 460-4, 2008/Sep/26. | Journal Article
2007
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme.
Janecki, Dariusz J⋅Bemis, Kerry G⋅Tegeler, Tony J⋅Sanghani, Paresh C⋅Zhai, Lanmin⋅Hurley, Thomas D⋅Bosron, William F and Wang, Mu
Analytical biochemistry, vol. 369, (no. 1), pp. 18-26, 2007/Oct/1. | Journal Article
 
Expression and characterization of a human carboxylesterase 2 splice variant.
Schiel, Marissa A⋅Green, Scheri-Lyn⋅Davis, Wilhelmina I⋅Sanghani, Paresh C⋅Bosron, William F and Sanghani, Sonal P
The Journal of pharmacology and experimental therapeutics, vol. 323, (no. 1), pp. 94-101, 2007/Oct. | Journal Article
2006
Absolute Quantification of ADH Isoenzymes in Human Liver using Multiple Reaction Monitoring (MRM) Method
Janecki, Dariusz J⋅Tegeler, Tony⋅Bemis, Kerry⋅Hurley, Thomas D⋅Bosron, William F and Wang, Mu
54th ASMS Conference Proceedings, 2006. | Journal Article
2005
Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide.
Quinney, S K⋅SK, Quinney⋅Quinney, Sk⋅Sanghani, Sonal P⋅SP, Sanghani⋅Sanghani, SP⋅Davis, WI⋅Davis, W I⋅WI, Davis⋅TD, Hurley⋅Hurley, T D⋅Hurley, TD⋅Sun, Z⋅Z, Sun⋅Sun, Z⋅DJ, Murry⋅Murry, Daryl J⋅Murry, DJ⋅Bosron, WF⋅Bosron, William F and WF, Bosron
The Journal of pharmacology and experimental therapeutics, vol. 313, (no. 3), pp. 1011-6, 2005/Jun. | Journal Article
2004
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3.
Sanghani, Sonal⋅Sanghani, Sonal P⋅Quinney, Sara⋅Quinney, Sara K⋅Fredenburg, Tyler B⋅Fredenburg, Tyler⋅Davis, Wilhelmina⋅Davis, Wilhelmina I⋅Murry, Daryl J⋅Murry, Daryl⋅Bosron, William and Bosron, William F
Drug metabolism and disposition: the biological fate of chemicals, vol. 32, (no. 5), pp. 505-11, 2004/May. | Journal Article
 
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1.
Sun, Zejin⋅Sun, Z.⋅Murry, Daryl J⋅Murry, D.J.⋅Sanghani, Sonal P⋅Sanghani, S.P.⋅Davis, Wilhelmina I⋅Davis, W.I.⋅Kedishvili, N.Y.⋅Kedishvili, Natalia Y⋅Zou, Q.⋅Zou, Qin⋅Hurley, Thomas D⋅Hurley, T.D.⋅Bosron, W.F. and Bosron, William F
The Journal of pharmacology and experimental therapeutics, vol. 310, (no. 2), pp. 469-76, 2004/Aug. | Journal Article
2003
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis.
Sanghani, Sonal⋅Sanghani, Sonal P⋅Sanghani, SP⋅Quinney, Sara K⋅Quinney, Sara⋅Quinney, Sk⋅Fredenburg, TB⋅Fredenburg, Tyler B⋅Fredenburg, Tyler⋅Sun, ZJ⋅Sun, Zejin⋅Sun, Zejin⋅Davis, WI⋅Davis, Wilhelmina⋅Davis, Wilhelmina I⋅Murry, Daryl J⋅Murry, Daryl⋅Murry, DJ⋅Cummings, OW⋅Cummings, Oscar⋅Cummings, Oscar W⋅Seitz, David⋅Seitz, DE⋅Seitz, David E⋅Bosron, William⋅Bosron, William F and Bosron, WF
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 9, (no. 13), pp. 4983-91, 2003/Oct/15. | Journal Article
 
Structure-function relationships in human Class III alcohol dehydrogenase (formaldehyde dehydrogenase).
Sanghani, Paresh C⋅Robinson, Howard⋅Bennett-Lovsey, Riccardo⋅Hurley, Thomas D and Bosron, William F
Chemico-biological interactions, vol. 143-144, pp. 195-200, 2003/Feb/1. | Journal Article
2002
Current progress on esterases: from molecular structure to function.
Satoh, Tetsuo⋅Taylor, Palmer⋅Bosron, William F⋅Sanghani, Sonal P⋅Hosokawa, Masakiyo and La Du, Bert N
Drug metabolism and disposition: the biological fate of chemicals, vol. 30, (no. 5), pp. 488-93, 2002/May. | Journal Article
 
Human glutathione-dependent formaldehyde dehydrogenase. Structural changes associated with ternary complex formation.
Sanghani, Paresh C⋅Bosron, William F and Hurley, Thomas D
Biochemistry, vol. 41, (no. 51), pp. 15189-94, 2002/Dec/24. | Journal Article
 
Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Sanghani, Paresh C⋅Robinson, Howard⋅Bosron, William F and Hurley, Thomas D
Biochemistry, vol. 41, (no. 35), pp. 10778-86, 2002/Sep/3. | Journal Article
 
Identification of microsomal rat liver carboxylesterases and their activity with retinyl palmitate.
Sanghani, Sonal P⋅Davis, Wilhelmina I⋅Dumaual, Natividad G⋅Mahrenholz, Alan and Bosron, William F
European journal of biochemistry / FEBS, vol. 269, (no. 18), pp. 4387-98, 2002/Sep. | Journal Article
 
Lessons from a bacterial cocaine esterase
Bosron, William F and Hurley, Thomas D
Nature Structural Biology, vol. 9, (no. 1), pp. 4-5, Jan 2002. | Journal Article
2001
Research advances in ethanol metabolism.
Ramchandani, Vijay A⋅Bosron, William F and Li, T K
Pathologie-biologie, vol. 49, (no. 9), pp. 676-82, 2001/Nov. | Journal Article
2000
Kinetic mechanism of human glutathione-dependent formaldehyde dehydrogenase.
Sanghani, Paresh C⋅PC, Sanghani⋅Stone, C L⋅CL, Stone⋅Ray, B D⋅BD, Ray⋅Pindel, E V⋅EV, Pindel⋅Hurley, T D⋅TD, Hurley⋅Bosron, William F and WF, Bosron
Biochemistry, vol. 39, (no. 35), pp. 10720-9, 2000/Sep/5. | Journal Article
1987
Ethanol metabolism.
Crabb, David W⋅Bosron, William F and Li, T K
Pharmacology & therapeutics, vol. 34, (no. 1), pp. 59-73, 1987. | Journal Article
1973
TPNH-LINKED ALDEHYDE REDUCTASE (Dissertation)
Bosron, William F (1973).