Dr. Klaunig's research has focused on understanding the toxicological and pathological effects of chemical agents including pharmaceuticals. His work has concentrated primarily in the area of chemically induced carcinogenesis with particular interest in the mechanisms by which agents induce liver and lung cancer.
Current Research
- Mechanistic Studies of Chemically Induced Liver Focal Necrosis in Rat
- Development of a Multiscale Mechanistic Computer Model of Acetaminophen Induced Liver Toxicity
- MOA Analysis of Liver Tumors In Rodents Induced by Organochlorine Insecticides
- Interaction of Environmental Chemical with the Progression of Nonalcoholic Fatty Liver Disease
- Mechanistic Investigation of Retro-Element Mediated Non-genotoxic Carcinogenicity in Rodents
- Understanding the Mechanism of PFOA Carcinogenesis in the Rodent and the Application of these Findings to Human Health Risk Assessment
Research: Carcinogenesis; Human health; Toxicology
Research Area:
- Environment and Human Health
Research Interests
- Nuclear receptor mediated toxicity
- Pesticide toxicity and human risk
- Cancer biology
- Dose response
- Risk assessment
- Carcinogenesis
- Toxicology
