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Dr. Klaunig's research has focused on understanding the toxicological and pathological effects of chemical agents including pharmaceuticals. His work has concentrated primarily in the area of chemically induced carcinogenesis with particular interest in the mechanisms by which agents induce liver and lung cancer.

Current Research

  1. Mechanistic Studies of Chemically Induced Liver Focal Necrosis in Rat
  2. Development of a Multiscale Mechanistic Computer Model of Acetaminophen Induced Liver Toxicity
  3. MOA Analysis of Liver Tumors In Rodents Induced by Organochlorine Insecticides
  4. Interaction of Environmental Chemical with the Progression of Nonalcoholic Fatty Liver Disease
  5. Mechanistic Investigation of Retro-Element Mediated Non-genotoxic Carcinogenicity in Rodents
  6. Understanding the Mechanism of PFOA Carcinogenesis in the Rodent and the Application of these Findings to Human Health Risk Assessment

Research: Carcinogenesis; Human health; Toxicology

Research Area:

  • Environment and Human Health

Research Interests

  • Nuclear receptor mediated toxicity
  • Pesticide toxicity and human risk
  • Cancer biology
  • Dose response
  • Risk assessment
  • Carcinogenesis
  • Toxicology
Public Health
PhD, University of Maryland, Experimental Pathology/Toxicology, 1980
MA, Montclair State University, Biology, 1976
BS, Ursinus College, Biology, 1973
alcohol education drug education health and medicine nervous system pharmacy & pharmacology cancer biology drug toxicity cancer or carcinogenesis prostate & testicular cancers liver disorders biomedical research training environmental health environmental health standards environmental medicine chemoprevention cancer prevention biochemical markers biological markers & sensor mechanisms cell lines genetic toxicology environmental biology environmental chemistry environmental effects toxicology water resources environmental impacts environmental toxicology prostate cancer
Academy of Toxicological Sciences
American Association for Cancer Research
American Association for the Advancement of Science
Environmental Mutagen Society
Society of Toxicologic Pathologists
Society of Toxicology