Expertise

Research, Clinical, and/or Academic Interests

  • Tissue nanotransfection, electroceutical infection management, nanomedicine and bioinformatics with the aim to develop a simple and point-of-care approach to achieve targeted epigenetic editing of adult diabetic ischemic tissue in vivo​
  • The molecular mechanism in diabetic vasculopathy and limb ischemia, employing tissue nanotransfection technology as a delivery platform to administer combination gene therapy for diabetic ischemic limb rescue

Keywords

  • Diabetic Wound Healing Impairment, Diabetes, Vasculopathy, Epigenetics, Wound Healing, Methylation, MicroRNA, Single cell RNA sequencing (scRNA-seq), Proteomics, Genetics, Spatial transcriptomics (Visium), Angiogenesis, Amputation, Immunology, Epithelial mesenchymal transition (EMT), Endothelial dysfunction, Molecular Biology.

Dr. Singh’s laboratory focuses on epigenetics of diabetic vasculopathy and wound healing.

His laboratory is investigating epigenetic mechanisms such as DNA methylation as a proxy for abnormal gene–environmental interactions in diabetic ischemic wounds.

Affiliations

Assistant Professor, Indiana Center for Regenerative Medicine and Engineering, Centers and Institutes, Indiana University School of Medicine

Associate Professor, Department of Surgery, School of Medicine, University of Pittsburgh

McGowan Institute for Regenerative Medicine, University of Pittsburgh Centers and Institutes, University of Pittsburgh

Past Affiliations

Post Doctoral Appointee, Department of Surgery, Indiana University School of Medicine

Degrees
PhD, Banaras Hindu University, Varanasi, India, Biotechnology, 2015
Honors

Translational and Regenerative Science Award, Wound Healing Foundation/Wound Healing Society, April, 2022

Junior Faculty award, Wound Healing Foundation, May, 2021

Young Investigator Award, Wound Healing Society, May, 2019

Scholarship for Notable Young Investigator Research, Wound Healing Foundation, April, 2018

Senior Research Fellowship, Department of Biotechnology, India, May, 2013

Junior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Govt. of India, December, 2010

Gold medal for standing first in B. Tech biotechnology, Sam Higginbottom University of Agriculture, Technology and Sciences, India, Sep, 2010

Trainee Travel Award, Wound Healing Foundation, July, 2020