Expertise
Dr. Singh’s laboratory at the Indiana Center for Regenerative Medicine and Engineering (ICRME) focuses on epigenetics of diabetic vasculopathy and wound healing.
  • Wound healing: His laboratory is investigating the epigenetic mechanisms such as DNA methylation as a proxy for abnormal gene–environmental interactions in diabetic ischemic wounds. Current line of study aims to develop a simple and point of care approach to achieve targeted epigenetic editing of adult diabetic ischemic tissue in vivo. The research is funded through peer-reviewed grant from Department of Defense (DoD).
  • Diabetic Vasculopathy: His laboratory is also investigating the molecular mechanism in diabetic vasculopathy and limb ischemia. His laboratory is applying single-cell RNA sequencing technology to study the endothelial cells of the human diabetic skin to identify novel ligands and receptors that can improve outcomes of the VEGF therapy. To that end, his team is employing ICRME’s Tissue Nanotransfection technology as a delivery platform to administer combination gene therapy for diabetic ischemic limb rescue.
Past Affiliations

Post Doctoral Appointee, Department of Surgery, Indiana University School of Medicine

Degrees
PhD, Banaras Hindu University, Biotechnology, 2015
Honors

Translational and Regenerative Science Award, Wound Healing Foundation/Wound Healing Society, April, 2022

Junior Faculty award, Wound Healing Foundation, May, 2021

Young Investigator Award, Wound Healing Society, May, 2019

Scholarship for Notable Young Investigator Research, Wound Healing Foundation, April, 2018

Senior Research Fellowship, Department of Biotechnology, India, May, 2013

Junior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Govt. of India, December, 2010

Gold medal for standing first in B. Tech biotechnology, Sam Higginbottom University of Agriculture, Technology and Sciences, India, Sep, 2010

Trainee Travel Award, Wound Healing Foundation, July, 2020