32 Publications (Page 1 of 2)
2024
Bridging population pharmacokinetic and semimechanistic absorption modeling of APX3330
Silva, Larissa L⋅Stratford, Robert E⋅Messmann, Richard⋅Kelley, Mark R and Quinney, Sara K
CPT: Pharmacometrics & Systems Pharmacology, vol. 13, (no. 1), pp. 106-117, Jan 2024. | Journal Article
2021
Novel Quantification of Extracellular Vesicles with Unaltered Surface Membranes Using an Internalized Oligonucleotide Tracer and Applied Pharmacokinetic Multiple Compartment Modeling
De Luca, Thomas⋅Stratford, Robert E⋅Stratford, Robert E.⋅Stratford, Robert E⋅Edwards, Madison E⋅Edwards, Madison E⋅Edwards, Madison E.⋅Ferreira, Christina R.⋅Ferreira, Christina R⋅Ferreira, Christina R⋅Benson, Eric A⋅Benson, Eric A. and Benson, Eric A
Pharmaceutical Research, vol. 38, (no. 10), pp. 1677-1695, Oct 2021. | Journal Article
2020
In search of healthy policy ecologies for education in relation to sustainability: Beyond evidence-based policy and post-truth politics
Stratford, Robert and Wals, Arjen
Policy Futures in Education, pp. 147821032090665, 2020. | Journal Article
 
Simultaneous Pharmacokinetic Analysis of Nitrate and its Reduced Metabolite, Nitrite, Following Ingestion of Inorganic Nitrate in a Mixed Patient Population
Coggan, Andrew R⋅Coggan, Andrew R.⋅Coggan, Andrew R.⋅Racette, Susan B.⋅Racette, Susan B.⋅Racette, Susan B⋅Thies, Dakkota⋅Thies, Dakkota⋅Peterson, Linda R.⋅Peterson, Linda R.⋅Peterson, Linda R⋅Stratford, Robert E.⋅Stratford, Robert E. and Stratford, Robert E
Pharmaceutical Research, vol. 37, (no. 12), Dec 2020. | Journal Article
2019
3552 Advancing Glioblastoma (GBM) drug regimen development to support combination therapy through integrated PKPD modeling and simulation-based predictions
Adhikari, Saugat⋅Adhikari, Saugat⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Pollok, Karen E⋅Pollok, Karen E⋅Stratford, Robert E and Stratford, Robert E
Journal of Clinical and Translational Science, vol. 3, (no. s1), pp. 2, 2019-03-00. | Journal Article
 
Comparison of In Vitro Stereoselective Metabolism of Bupropion in Human, Monkey, Rat, and Mouse Liver Microsomes
Bhattacharya, Chandrali⋅Bhattacharya, Chandrali⋅Kirby, Danielle⋅Kirby, Danielle⋅Van Stipdonk, Michael⋅Van Stipdonk, Michael⋅Stratford, Robert and Stratford, Robert
European Journal of Drug Metabolism and Pharmacokinetics, vol. 44, (no. 2), pp. 274, 20190409. | Journal Article
 
Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs
Hasan, Mahmud⋅Marzouk, Mohamed Akmal⋅Adhikari, Saugat⋅Wright, Thomas D⋅Miller, Benton P⋅Matossian, Margarite D⋅Elliott, Steven⋅Wright, Maryl⋅Alzoubi, Madlin⋅Collins-Burow, Bridgette M⋅Burow, Matthew E⋅Holzgrabe, Ulrike⋅Zlotos, Darius P⋅Stratford, Robert E and Witt-Enderby, Paula A
Molecular pharmacology, vol. 96, (no. 2), pp. 296, 2019-08-00. | Journal Article
2018
Cellular Pharmacokinetic Model-Based Analysis of Genistein, Glyceollin, and MK-571 Effects on 5 (and 6)-Carboxy-2′,7′-Dichloroflourescein Disposition in Caco-2 Cells
Drennen, Callie⋅Gorse, Erin and Stratford, Robert E
Journal of Pharmaceutical Sciences, vol. 107, (no. 4), pp. 1203, April 2018. | Journal Article
 
Drug conjugates—an emerging approach to treat breast cancer
Hasan, Mahmud⋅Leak, Rehana K⋅Stratford, Robert E⋅Zlotos, Darius P and Witt‐Enderby, Paula A
Pharmacology Research & Perspectives, vol. 6, (no. 4), pp. n/a, July 2018. | Journal Article
2016
Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions
Chimezie, Chukwuemezie⋅Ewing, Adina⋅Schexnayder, Chandler⋅Bratton, Melyssa⋅Glotser, Elena⋅Skripnikova, Elena⋅Sá, Pedro⋅Boué, Stephen and Stratford, Robert E
Journal of Pharmaceutical Sciences, vol. 105, (no. 2), pp. 981, February 2016. | Journal Article
2015
Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists
Liu, Bin⋅Croy, Carrie H⋅Hitchcock, Stephen A⋅Allen, Jennifer R⋅Rao, Zhigang⋅Evans, David⋅Bures, Mark G⋅McKinzie, David L⋅Watt, Marla Leigh⋅Stuart Gregory, G⋅Hansen, Marvin M⋅Hoogestraat, Paul J⋅Jamison, James A⋅Okha-Mokube, Fese M⋅Stratford, Robert E⋅Turner, William⋅Bymaster, Frank and Felder, Christian C
Bioorganic & Medicinal Chemistry Letters, vol. 25, (no. 19), pp. 4163, 2015-10-01. | Journal Article
 
Genistein and Glyceollin Effects on ABCC2 (MRP2) and ABCG2 (BCRP) in Caco-2 Cells
Schexnayder, Chandler and Stratford, Robert E
International journal of environmental research and public health, vol. 13, (no. 1), pp. ijerph13010017, 2015-Dec-22. | Journal Article
2014
Glyceollin Transport, Metabolism, and Effects on P-Glycoprotein Function in Caco-2 Cells
Chimezie, Chukwuemezie⋅Chimezie, Chukwuemezie⋅Ewing, Adina C⋅Ewing, Adina C⋅Quadri, Syeda S⋅Quadri, Syeda S⋅Cole, Richard B⋅Cole, Richard B⋅Boue, Stephen M⋅Boué, Stephen M⋅Omari, Christopher F⋅Omari, Christopher F⋅Bratton, Melyssa⋅Bratton, Melyssa⋅Glotser, Elena⋅Glotser, Elena⋅Skripnikova, Elena⋅Skripnikova, Elena⋅Townley, Ian⋅Townley, Ian⋅Stratford, Robert E and Stratford, Robert E
Journal of Medicinal Food, vol. 17, (no. 4), pp. 471, 2014-04-01. | Journal Article
 
Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics
Li, Claire H⋅Li, Claire H⋅Stratford, Robert E⋅Stratford, Robert E⋅Velez de Mendizabal, Nieves⋅Velez de Mendizabal, Nieves⋅Cremers, Thomas I⋅Cremers, Thomas I F H⋅Pollock, Bruce G⋅Pollock, Bruce G⋅Mulsant, Benoit H⋅Mulsant, Benoit H⋅Remington, Gary⋅Remington, Gary⋅Bies, Robert R and Bies, Robert R
Journal of Translational Medicine , vol. 12, pp. 203, 2014. | Journal Article
2013
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models
Martinez-Perez, Jose A⋅Iyengar, Smriti⋅Shannon, Harlan E⋅Bleakman, David⋅Alt, Andrew⋅Arnold, Brian M⋅Bell, Michael G⋅Bleisch, Thomas J⋅Castaño, Ana M⋅Del Prado, Miriam⋅Dominguez, Esteban⋅Escribano, Ana M⋅Filla, Sandra A⋅Ho, Ken H⋅Hudziak, Kevin J⋅Jones, Carrie K⋅Mateo, Ana⋅Mathes, Brian M⋅Mattiuz, Edward L⋅Ogden, Ann Marie L⋅Simmons, Rosa Maria A⋅Stack, Douglas R⋅Stratford, Robert E⋅Winter, Mark A⋅Wu, Zhipei and Ornstein, Paul L
Bioorganic & Medicinal Chemistry Letters, vol. 23, (no. 23), pp. 6462, 2013-12-01. | Journal Article
 
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy
Martinez-Perez, Jose A⋅Iyengar, Smriti⋅Shannon, Harlan E⋅Bleakman, David⋅Alt, Andrew⋅Clawson, David K⋅Arnold, Brian M⋅Bell, Michael G⋅Bleisch, Thomas J⋅Castaño, Ana M⋅Del Prado, Miriam⋅Dominguez, Esteban⋅Escribano, Ana M⋅Filla, Sandra A⋅Ho, Ken H⋅Hudziak, Kevin J⋅Jones, Carrie K⋅Mateo, Ana⋅Mathes, Brian M⋅Mattiuz, Edward L⋅Ogden, Ann Marie L⋅Simmons, Rosa Maria A⋅Stack, Douglas R⋅Stratford, Robert E⋅Winter, Mark A⋅Wu, Zhipei and Ornstein, Paul L
Bioorganic & Medicinal Chemistry Letters, vol. 23, (no. 23), pp. 6466, 2013-12-01. | Journal Article
2012
Microdialysis Evaluation of Clozapine and N-Desmethylclozapine Pharmacokinetics in Rat Brain
Cremers, Thomas I⋅Cremers, Thomas⋅Flik, Gunnar⋅Flik, Gunnar⋅Hofland, Corry⋅Hofland, Corry⋅Stratford, Robert and Stratford, Robert
Drug Metabolism and Disposition, vol. 40, (no. 10), pp. 1916, 2012-10. | Journal Article
2011
'When you looked at me, you didn't judge me': supporting transient students and their families in New Zealand primary schools
Mutch, Carol⋅Mutch, Carol Anne⋅Rarere, Vivienne⋅Rarere, Vivienne⋅Stratford, Robert and Stratford, Robert
Pastoral Care in Education: International Associate Editors, vol. 29, (no. 4), pp. 245, 12/1/2011. | Journal Article
2009
Microdialysis Evaluation of Atomoxetine Brain Penetration and Central Nervous System Pharmacokinetics in Rats
Kielbasa, William⋅Kalvass, J. and Stratford, Robert
Drug Metabolism and Disposition, vol. 37, (no. 1), pp. 142, 20090101. | Journal Article
2006
Pharmacological Characterization of the Competitive GLUK5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo
Weiss, Brianne⋅Alt, Andrew⋅Ogden, Ann⋅Gates, Mary⋅Dieckman, Donna⋅Clemens-Smith, Amy⋅Ho, Ken⋅Jarvie, Keith⋅Rizkalla, Geihan⋅Wright, Rebecca⋅Calligaro, David⋅Schoepp, Darryle⋅Mattiuz, Edward⋅Stratford, Robert⋅Johnson, Bryan⋅Salhoff, Craig⋅Katofiasc, Mary⋅Phebus, Lee⋅Schenck, Kathryn⋅Cohen, Marlene⋅Filla, Sandra⋅Ornstein, Paul⋅Johnson, Kirk and Bleakman, David
Journal of Pharmacology and Experimental Therapeutics, vol. 318, (no. 2), pp. 781, 20060801. | Journal Article
2005
Dipeptides as Effective Prodrugs of the Unnatural Amino Acid (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740), a Selective Group II Metabotropic Glutamate Receptor Agonist
Bueno, Ana Belén⋅Collado, Iván⋅de Dios, Alfonso⋅Domínguez, Carmen⋅Martín, José Alfredo⋅Martín, Luisa M⋅Martínez-Grau, María Angeles⋅Montero, Carlos⋅Pedregal, Concepción⋅Catlow, John⋅Coffey, D. Scott⋅Clay, Michael P⋅Dantzig, Anne H⋅Lindstrom, Terry⋅Monn, James A⋅Jiang, Haiyan⋅Schoepp, Darryle D⋅Stratford, Robert E⋅Tabas, Linda B⋅Tizzano, Joseph P⋅Wright, Rebecca A and Herin, Marc F
Journal of Medicinal Chemistry, vol. 48, (no. 16), pp. 5320, 20050811. | Journal Article
 
Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain
Dominguez, Esteban⋅Iyengar, Smriti⋅Shannon, Harlan E⋅Bleakman, David⋅Alt, Andrew⋅Arnold, Brian M⋅Bell, Michael G⋅Bleisch, Thomas J⋅Buckmaster, Jennifer L⋅Castano, Ana M⋅Del Prado, Miriam⋅Escribano, Ana⋅Filla, Sandra A⋅Ho, Ken H⋅Hudziak, Kevin J⋅Jones, Carrie K⋅Martinez-Perez, Jose A⋅Mateo, Ana⋅Mathes, Brian M⋅Mattiuz, Edward L⋅Ogden, Ann Marie L⋅Simmons, Rosa Maria A⋅Stack, Douglas R⋅Stratford, Robert E⋅Winter, Mark A⋅Wu, Zhipei and Ornstein, Paul L
Journal of Medicinal Chemistry, vol. 48, (no. 13), pp. 4203, 20050630. | Journal Article
2002
ChemInform Abstract: Three‐Dimensional Quantitative Structure—Permeability Relationship Analysis for a Series of Inhibitors of Rhinovirus Replication
Ekins, Sean⋅Durst, Gregory L⋅Stratford, Robert E⋅Thorner, David A⋅Lewis, Richard⋅Loncharich, Richard J and Wikel, James H
ChemInform, vol. 33, (no. 9), pp. no, March 5, 2002. | Journal Article
 
Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester:  A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Models of Acute Migraine
Filla, Sandra A⋅Winter, Mark A⋅Johnson, Kirk W⋅Bleakman, David⋅Bell, Michael G⋅Bleisch, Thomas J⋅Castaño, Ana M⋅Clemens-Smith, Amy⋅del Prado, Miriam⋅Dieckman, Donna K⋅Dominguez, Esteban⋅Escribano, Ana⋅Ho, Ken H⋅Hudziak, Kevin J⋅Katofiasc, Mary A⋅Martinez-Perez, Jose A⋅Mateo, Ana⋅Mathes, Brian M⋅Mattiuz, Edward L⋅Ogden, Ann Marie L⋅Phebus, Lee A⋅Stack, Douglas R⋅Stratford, Robert E and Ornstein, Paul L
Journal of Medicinal Chemistry, vol. 45, (no. 20), pp. 4386, 20020926. | Journal Article
2001
Three-Dimensional Quantitative Structure-Permeability Relationship Analysis for a Series of Inhibitors of Rhinovirus Replication
Ekins, Sean⋅Durst, Gregory L⋅Stratford, Robert E⋅Thorner, David A⋅Lewis, Richard⋅Loncharich, Richard J and Wikel, James H
Journal of Chemical Information and Computer Sciences, vol. 41, (no. 6), pp. 1586, 20011126. | Journal Article