145 Publications (Page 1 of 6)
2024
APOE loss of function: A genetic shield against Alzheimer’s disease. Neuron
. | Journal Article
 
Effects of SPI1-mediated transcriptome remodeling on Alzheimer’s disease-related phenotypes in mouse models of Aβ amyloidosis. Nature Communications
. | Journal Article
 
Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity
2023
A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer’s disease risk and rates of disease progression
Bae, Jinhyeong⋅Logan, Paige E.⋅Acri, Dominic J.⋅Bharthur, Apoorva⋅Nho, Kwangsik⋅Saykin, Andrew J.⋅Risacher, Shannon L.⋅Nudelman, Kelly⋅Polsinelli, Angelina J.⋅Pentchev, Valentin⋅Kim, Jungsu⋅Hammers, Dustin B. and and, Liana G. Apostolova
Alzheimer’s &\mathsemicolon Dementia. | Journal Article
 
Endogenous recapitulation of Alzheimer?s disease neuropathology through human 3D direct neuronal reprogramming
Sun, Z.⋅Kwon, J.-S.⋅Ren, Y.⋅Chen, S.⋅Cates, K.⋅Lu, X.⋅Walker, C.K.⋅Karahan, H.⋅Sviben, S.⋅Fitzpatrick, J.A.J.⋅Valdez, C.⋅Houlden, H.⋅Karch, C.M.⋅Bateman, R.J.⋅Sato, C.⋅Mennerick, S.J.⋅Diamond, M.I.⋅Kim, J.⋅Tanzi, R.E.⋅Holtzman, D.M. and Yoo, A.S.
 
Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer ′s disease
 
Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
Lancaster, M.S.⋅Kim, B.⋅Doud, E.H.⋅Tate, M.D.⋅Sharify, A.D.⋅Gao, H.⋅Chen, D.⋅Simpson, E.⋅Gillespie, P.⋅Chu, X.⋅Miller, M.J.⋅Wang, Y.⋅Liu, Y.⋅Mosley, A.L. and Graham, B.H.
Cell Reports, vol. 42. | Journal Article
 
Network analysis identifies strain-dependent response to tau and tau seeding-associated genes
Acri, D.J.⋅You, Y.⋅Tate, M.D.⋅Karahan, H.⋅Martinez, P.⋅McCord, B.⋅Sharify, A.D.⋅John, S.⋅Kim, B.⋅Dabin, L.C.⋅Philtjens, S.⋅Wijeratne, H.R.S.⋅McCray, T.J.⋅Smith, D.C.⋅Bissel, S.J.⋅Lamb, B.T. and Lasagna-Reeves, C.A.
The Journal of experimental medicine, vol. 220. | Journal Article
 
Network analysis reveals strain-dependent response to misfolded tau aggregates. BioRxiv
. | Journal Article
 
The effect of Abi3 locus deletion on the progression of Alzheimer’s disease-related pathologies
Karahan, Hande⋅Smith, Daniel C.⋅Kim, Byungwook⋅McCord, Brianne⋅Mantor, Jordan⋅John, Sutha K.⋅Al-Amin, Md Mamun⋅Dabin, Luke C. and Kim, Jungsu
Frontiers in Immunology, vol. 14. | Journal Article
 
TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo. Cells
Lee-Gosselin, Audrey⋅Jury-Garfe, Nur⋅You, Yanwen⋅Dabin, Luke⋅Soni, Disha⋅Dutta, Sayan⋅Rochet, Jean-Christophe⋅Kim, Jungsu⋅Oblak, Adrian L. and Lasagna-Reeves, Cristian A.
. | Journal Article
2022
Deletion of the Alzheimer’s disease risk gene Abi3 locus results in obesity and systemic metabolic disruption in mice
Smith, Daniel C.⋅Karahan, Hande⋅Wijeratne, H. R. Sagara⋅Al-Amin, Mamun⋅McCord, Brianne⋅Moon, Younghye and Kim, Jungsu
Frontiers in Aging Neuroscience, vol. 14. | Journal Article
2021
Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer?s disease in a mouse model of A? amyloidosis
Karahan, H.⋅Smith, D.C.⋅Kim, B.⋅Dabin, L.C.⋅Al-Amin, M.M.⋅Sagara Wijeratne, H.R.⋅Pennington, T.⋅Prisco, G.V.D.⋅McCord, B.⋅Lin, P.B.-C.⋅Li, Y.⋅Peng, J.⋅Oblak, A.L.⋅Chu, S.⋅Atwood, B.K. and Kim, J.
Science Advances, vol. 7. | Journal Article
 
Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer s disease in a mouse model of A beta amyloidosis. Science Advances
. | Journal Article
 
Identification of Genetic Variants Regulating the Abundance of Clinically Relevant Plasma Proteins using the Diversity Outbred Mouse Model
Philtjens, S.⋅Acri, D.J. and Kim, B.
 
MicroRNAs on the move: microRNAs in astrocyte-derived ApoE particles regulate neuronal function.
Karahan, Hande⋅Dabin, Luke C⋅Tate, Mason D and Kim, Jungsu
Neuron, vol. 109, (no. 6), pp. 907-909, March 17, 2021. | Journal Article
 
Tubular human brain organoids to model microglia-mediated neuroinflammation
Ao, Zheng⋅Cai, Hongwei⋅Wu, Zhuhao⋅Song, Sunghwa⋅Karahan, Hande⋅Kim, Byungwook⋅Lu, Hui-Chen⋅Kim, Jungsu⋅Mackie, Ken and Guo, Feng
Lab on a Chip. | Journal Article
2020
Acoustofluidic assembly of 3D neurospheroids to model alzheimer?s disease
Cai, H.⋅Ao, Z.⋅Hu, L.⋅Moon, Y.⋅Wu, Z.⋅Lu, H.-C.⋅Kim, J. and Guo, F.
 
Acoustofluidic assembly of 3D neurospheroids to model Alzheimer s disease.
The Analyst. | Journal Article
 
Chemogenetic activation of astrocytes in the hippocampus and cortex changes the transcriptome of microglia and other cell types.
Philtjens, Stéphanie⋅Turnbull, Marion T.⋅Thedy, Brian P.⋅Moon, Younghye and Kim, Jungsu
Cold Spring Harbor Laboratory
 
Disrupted structural connectivity in ArcA\upbeta mouse model of A\upbeta amyloidosis
Al-Amin, Md. Mamun⋅Grandjean, Joanes⋅Klohs, Jan and Kim, Jungsu
Cold Spring Harbor Laboratory
 
Erratum: Correction to: Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy (Acta neuropathologica communications (2020) 8 1 (72))
Kempthorne, L.⋅Yoon, H.⋅Madore, C.⋅Smith, S.⋅Wszolek, Z.K.⋅Rademakers, R.⋅Kim, J.⋅Butovsky, O. and Dickson, D.W.
Acta neuropathologica communications, vol. 8, pp. 90. | Journal Article
 
Identification of genetic variants regulating the abundance of clinically relevant plasma proteins using the Diversity Outbred mouse model
 
Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy
Kempthorne, L.⋅Yoon, H.⋅Madore, C.⋅Smith, S.⋅Wszolek, Z.K.⋅Rademakers, R.⋅Kim, J.⋅Butovsky, O. and Dickson, D.W.
Acta Neuropathologica Communications, vol. 8. | Journal Article
 
Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy. Acta Neuropathologica Communications
. | Journal Article