27 Publications (Page 1 of 2)
2021
TRACT revisited: an algebraic solution for determining overall rotational correlation times from cross-correlated relaxation ratesRobson, Scott A⋅⋅Wu, Hongwei and Ziarek, Joshua JJournal of Biomolecular NMR, vol. 75, (no. 8-9), pp. 293-302, Sep 2021.
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2018
15 N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteinsChhabra, Sandeep⋅Chhabra, Sandeep⋅Fischer, Patrick⋅Fischer, Patrick⋅Takeuchi, Koh⋅Takeuchi, Koh⋅Dubey, Abhinav⋅Dubey, Abhinav⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Boeszoermenyi, Andras⋅Boeszoermenyi, Andras⋅Mathieu, Daniel⋅Mathieu, Daniel⋅Bermel, Wolfgang⋅Bermel, Wolfgang⋅Davey, Norman E⋅Davey, Norman E⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Arthanari, Haribabu and Arthanari, HaribabuProceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 8), pp. E1710, 2018-02-20.
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15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteinsChhabra, Sandeep⋅Chhabra, Sandeep⋅Fischer, Patrick⋅Fischer, Patrick⋅Takeuchi, Koh⋅Takeuchi, Koh⋅Dubey, Abhinav⋅Dubey, Abhinav⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Boeszoermenyi, Andras⋅Boeszoermenyi, Andras⋅Mathieu, Daniel⋅Mathieu, Daniel⋅Bermel, Wolfgang⋅Bermel, Wolfgang⋅Davey, Norman E⋅Davey, Norman E⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Arthanari, Haribabu and Arthanari, HaribabuProceedings of the National Academy of Sciences, vol. 115, (no. 8), pp. E1719, 2018-02-20.
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Biased antagonism of CXCR4 avoids antagonist toleranceHitchinson, Ben⋅Hitchinson, Ben⋅Hitchinson, Ben⋅Eby, Jonathan M⋅Eby, Jonathan M⋅Eby, Jonathan M⋅Gao, Xianlong⋅Gao, Xianlong⋅Gao, Xianlong⋅Guite-Vinet, Francois⋅Guite-Vinet, Francois⋅Guite-Vinet, Francois⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Abdelkarim, Hazem⋅Abdelkarim, Hazem⋅Abdelkarim, Hazem⋅Lee, Youngshim⋅Lee, Youngshim⋅Lee, Youngshim⋅Okamoto, Yukari⋅Okamoto, Yukari⋅Okamoto, Yukari⋅Shikano, Sojin⋅Shikano, Sojin⋅Shikano, Sojin⋅Majetschak, Matthias⋅Majetschak, Matthias⋅Majetschak, Matthias⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Volkman, Brian F⋅Volkman, Brian F⋅Volkman, Brian F⋅Tarasova, Nadya I⋅Tarasova, Nadya I⋅Tarasova, Nadya I⋅Gaponenko, Vadim⋅Gaponenko, Vadim and Gaponenko, VadimScience signaling, vol. 11, (no. 552), pp. eaat2214, 2018-Oct-16.
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Bicelle size modulates the rate of bacteriorhodopsin foldingGruenhagen, Timothy C⋅Gruenhagen, Timothy C⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Schlebach, Jonathan P and Schlebach, Jonathan PProtein Science, vol. 27, (no. 6), pp. 1112, 2018-06-00.
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Recent developments in solution nuclear magnetic resonance (NMR)-based molecular biologyZiarek, Joshua J⋅Ziarek, Joshua⋅Baptista, Diego⋅Baptista, Diego⋅Wagner, Gerhard and Wagner, GerhardJournal of Molecular Medicine, vol. 96, (no. 1), pp. 8, 20180100.
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Recent developments in solution nuclear magnetic resonance (NMR)-based molecular biologyZiarek, Joshua⋅Ziarek, Joshua J⋅Baptista, Diego⋅Baptista, Diego⋅Wagner, Gerhard and Wagner, GerhardJournal of Molecular Medicine, vol. 96, (no. 1), pp. 1-8, Jan 2018.
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sup 15^N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteinsChhabra, Sandeep⋅Chhabra, Sandeep⋅Fischer, Patrick⋅Fischer, Patrick⋅Takeuchi, Koh⋅Takeuchi, Koh⋅Dubey, Abhinav⋅Dubey, Abhinav⋅Ziarek, Joshua⋅Ziarek, Joshua⋅Boeszoermenyi, Andras⋅Boeszoermenyi, Andras⋅Mathieu, Daniel⋅Mathieu, Daniel⋅Bermel, Wolfgang⋅Bermel, Wolfgang⋅Davey, Norman⋅Davey, Norman⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Arthanari, Haribabu and Arthanari, HaribabuProceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 8), pp. E1710, 20180220.
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2017
Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activationZiarek, Joshua J⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Kleist, Andrew B⋅Kleist, Andrew B⋅Kleist, Andrew B⋅London, Nir⋅London, Nir⋅London, Nir⋅Raveh, Barak⋅Raveh, Barak⋅Raveh, Barak⋅Montpas, Nicolas⋅Montpas, Nicolas⋅Montpas, Nicolas⋅Bonneterre, Julien⋅Bonneterre, Julien⋅Bonneterre, Julien⋅St-Onge, Geneviève⋅St-Onge, Geneviève⋅St-Onge, Geneviève⋅DiCosmo-Ponticello, Crystal J⋅DiCosmo-Ponticello, Crystal J⋅DiCosmo-Ponticello, Crystal J⋅Koplinski, Chad A⋅Koplinski, Chad A⋅Koplinski, Chad A⋅Roy, Ishan⋅Roy, Ishan⋅Roy, Ishan⋅Stephens, Bryan⋅Stephens, Bryan⋅Stephens, Bryan⋅Thelen, Sylvia⋅Thelen, Sylvia⋅Thelen, Sylvia⋅Veldkamp, Christopher T⋅Veldkamp, Christopher T⋅Veldkamp, Christopher T⋅Coffman, Frederick D⋅Coffman, Frederick D⋅Coffman, Frederick D⋅Cohen, Marion C⋅Cohen, Marion C⋅Cohen, Marion C⋅Dwinell, Michael B⋅Dwinell, Michael B⋅Dwinell, Michael B⋅Thelen, Marcus⋅Thelen, Marcus⋅Thelen, Marcus⋅Peterson, Francis C⋅Peterson, Francis C⋅Peterson, Francis C⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Volkman, Brian F⋅Volkman, Brian F and Volkman, Brian FScience signaling, vol. 10, (no. 471), pp. eaah5756, 2017-Mar-21.
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2016
Behavioural interseasonal adaptations in Daphnia pulicaria (Crustacea: Cladocera) as induced by predation infochemicalsNihongi, Ai⋅Ziarek, Joshua⋅Uttieri, Marco⋅Sandulli, Roberto⋅Zambianchi, Enrico and Strickler, JAquatic Ecology, vol. 50, (no. 4), pp. 684, 20161200.
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New paradigms in chemokine receptor signal transduction: Moving beyond the two-site modelKleist, Andrew B⋅Kleist, Andrew B⋅Getschman, Anthony E⋅Getschman, Anthony E⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Nevins, Amanda M⋅Nevins, Amanda M⋅Gauthier, Pierre-Arnaud⋅Gauthier, Pierre-Arnaud⋅Chevigné, Andy⋅Chevigné, Andy⋅Szpakowska, Martyna⋅Szpakowska, Martyna⋅Volkman, Brian F and Volkman, Brian FBiochemical Pharmacology, vol. 114, pp. 68, 2016-08-15.
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2014
Discovery and Characterization of a Disulfide-Locked C2-Symmetric Defensin PeptideWommack, Andrew J⋅Wommack, Andrew J⋅Wommack, Andrew J⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Tomaras, Jill⋅Tomaras, Jill⋅Tomaras, Jill⋅Chileveru, Haritha R⋅Chileveru, Haritha R⋅Chileveru, Haritha R⋅Zhang, Yunfei⋅Zhang, Yunfei⋅Zhang, Yunfei⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Nolan, Elizabeth M⋅Nolan, Elizabeth M and Nolan, Elizabeth MJournal of the American Chemical Society, vol. 136, (no. 39), pp. 13497, 2014-10-00.
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Discovery and characterization of a disulfide-locked [C.sub.2]-symmetric defensin peptideWommack, Andrew⋅Wommack, Andrew⋅Ziarek, Joshua⋅Ziarek, Joshua⋅Tomaras, Jill⋅Tomaras, Jill⋅Chileveru, Haritha⋅Chileveru, Haritha⋅Zhang, Yunfei⋅Zhang, Yunfei⋅Wagner, Gerhard⋅Wagner, Gerhard⋅Nolan, Elizabeth and Nolan, ElizabethJournal of the American Chemical Society, vol. 136, (no. 39), pp. 13494, 20141001.
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Examining weak protein-protein interactions in start codon recognition via nuclear magnetic resonance spectroscopyLuna, Rafael E⋅Luna, Rafael E⋅Akabayov, Sabine R⋅Akabayov, Sabine R⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Wagner, Gerhard and Wagner, GerhardThe FEBS journal, vol. 281, (no. 8), pp. 1973, 2014-01-02.
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Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 ChemokineSmith, Emmanuel W⋅Smith, Emmanuel W⋅Liu, Yan⋅Liu, Yan⋅Getschman, Anthony E⋅Getschman, Anthony E⋅Peterson, Francis C⋅Peterson, Francis C⋅Ziarek, Joshua J⋅Ziarek, Joshua J⋅Li, Rongshi⋅Li, Rongshi⋅Volkman, Brian F⋅Volkman, Brian F⋅Chen, Yu and Chen, YuJournal of Medicinal Chemistry, vol. 57, (no. 22), pp. 9699, 20141126.
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2013
Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N TerminusZiarek, Josh⋅Ziarek, Joshua J⋅Veldkamp, Christopher T⋅Veldkamp, Christopher⋅Zhang, Fuming⋅Zhang, Fuming⋅Murray, Nathan J⋅Murray, Nathan J⋅Kartz, Gabriella A⋅Kartz, Gabriella A⋅Liang, Xinle⋅Liang, Xinle⋅Su, Jidong⋅Su, Jidong⋅Baker, John E⋅Baker, John E⋅Linhardt, Robert J⋅Linhardt, Robert J⋅Volkman, Brian F and Volkman, Brian FThe Journal of biological chemistry, vol. 288, (no. 1), pp. 746, 2013-Jan-04.
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Sulfopeptide Probes of the CXCR4/CXCL12 Interface Reveal Oligomer-Specific Contacts and Chemokine AllosteryZiarek, Joshua J⋅Ziarek, Josh⋅Ziarek, Joshua J⋅Getschman, Anthony E⋅Getschman, Anthony E⋅Getschman, Anthony E⋅Butler, Stephen J⋅Butler, Stephen J⋅Butler, Stephen J⋅Taleski, Deni⋅Taleski, Deni⋅Taleski, Deni⋅Stephens, Bryan⋅Stephens, Bryan⋅Stephens, Bryan⋅Kufareva, Irina⋅Kufareva, Irina⋅Kufareva, Irina⋅Handel, Tracy M⋅Handel, Tracy M⋅Handel, Tracy M⋅Payne, Richard J⋅Payne, Richard J⋅Payne, Richard J⋅Volkman, Brian F⋅Volkman, Brian F and Volkman, Brian FACS Chemical Biology, vol. 8, (no. 9), pp. 1963, 20130920.
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2012
Fragment-Based Optimization of Small Molecule CXCL12 Inhibitors for Antagonizing the CXCL12/CXCR4 InteractionZiarek, Joshua⋅Ziarek, Josh⋅Liu, Yan⋅Liu, Yan⋅Smith, Emmanuel⋅Smith, Emmanuel⋅Zhang, Guolin⋅Zhang, Guolin⋅Peterson, Francis⋅Peterson, Francis⋅Chen, Jun⋅Chen, Jun⋅Yu, Yongping⋅Yu, Yongping⋅Chen, Yu⋅Chen, Yu⋅Volkman, Brian⋅Volkman, Brian F⋅Li, Rongshi and Li, RongshiCurrent Topics in Medicinal Chemistry, vol. 12, (no. 24), pp. 2740, 2012-December.
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NMR in the analysis of functional chemokine interactions and drug discoveryZiarek, Joshua J⋅Ziarek, Joshua J⋅Volkman, Brian F and Volkman, Brian FDrug Discovery Today: Technologies, vol. 9, (no. 4), pp. e299, Winter 2012.
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Structure-based ligand discovery for the protein—protein interface of chemokine receptor CXCR4Mysinger, Michael M⋅Mysinger, Michael⋅Weiss, Dahlia R⋅Weiss, Dahlia⋅Ziarek, Josh⋅Ziarek, Joshua⋅Gravel, Stéphanie⋅Gravel, Stéphanie⋅Doak, Allison K⋅Doak, Allison⋅Karpiak, Joel⋅Karpiak, Joel⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Shoichet, Brian K⋅Shoichet, Brian⋅Volkman, Brian F and Volkman, BrianProceedings of the National Academy of Sciences of the United States of America, vol. 109, (no. 14), pp. 5522, 20120403.
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2011
Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approachZiarek, Josh⋅Ziarek, Joshua J⋅Peterson, Francis C⋅Peterson, Francis⋅Lytle, Betsy L⋅Lytle, Betsy L⋅Volkman, Brian F and Volkman, Brian FMethods in enzymology, vol. 493, pp. 275, 2011-00-00.
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CXCL12 Oligomerization Dictates Divergent Signaling and Migratory Responses in Intestinal Epithelial CellsDrury, Luke⋅Ziarek, Joshua⋅Volkman, Brian and Dwinell, MichaelGastroenterology, vol. 140, (no. 5), pp. S-645, 2011.
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Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathwaysDrury, Luke⋅Drury, Luke J⋅Ziarek, Joshua⋅Ziarek, Josh⋅Gravel, Stéphanie⋅Gravel, Stéphanie⋅Veldkamp, Christopher⋅Veldkamp, Christopher⋅Takekoshi, Tomonori⋅Takekoshi, Tomonori⋅Hwang, Samuel⋅Hwang, Sam T⋅Heveker, Nikolaus⋅Heveker, Nikolaus⋅Volkman, Brian F⋅Volkman, Brian⋅Dwinell, Michael and Dwinell, Michael BProceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 43), pp. 17660, 20111025.
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Seasonal adaptations of Daphnia pulicaria swimming behaviour: the effect of water temperatureZiarek, Joshua⋅Ziarek, Joshua⋅Nihongi, Ai⋅Nihongi, Ai⋅Nagai, Takeyoshi⋅Nagai, Takeyoshi⋅Uttieri, Marco⋅Uttieri, Marco⋅Strickler, J and Strickler, JHydrobiologia, vol. 661, (no. 1), pp. 327, 20110200.
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The CXC Chemokine Receptor 4 Ligands Ubiquitin and Stromal Cell-derived Factor-1α Function through Distinct Receptor InteractionsSaini, Vikas⋅Saini, Vikas⋅Staren, Daniel M⋅Staren, Daniel M⋅Ziarek, Joshua J⋅Ziarek, Josh⋅Nashaat, Zayd N⋅Nashaat, Zayd N⋅Campbell, Edward M⋅Campbell, Edward M⋅Volkman, Brian F⋅Volkman, Brian F⋅Marchese, Adriano⋅Marchese, Adriano⋅Majetschak, Matthias and Majetschak, MatthiasThe Journal of biological chemistry, vol. 286, (no. 38), pp. 33477, 2011-Sep-23.
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