Expertise

Dr. Kim’s laboratory is interested in understanding the molecular and cellular basis of neuronal and glial dysfunction in Alzheimer’s disease, other aging-associated neurodegenerative diseases, and normal brain aging. Research in our lab is aimed at developing therapeutic strategies for Alzheimer’s disease by targeting brain lipid-regulating proteins, such as apolipoprotein E (ApoE), low density lipoprotein receptor (LDLR), and ATP-binding cassette transporter A1 (ABCA1). We are also interested in the role of epigenetics and non-coding RNAs in the pathogenesis of Alzheimer’s disease and other aging-associated neurodegenerative diseases.

The main interest of Kim lab is to understand the pathogenic mechanisms of Alzheimer’s disease and other neurodegenerative diseases (Parkinson's disease, Frontotemporal dementia, Huntington's disease, and Amyotrophic Lateral Sclerosis) and to identify novel therapeutic targets.

In addition, we are investigating whether microRNAs of our interest affect cardiovascular diseases, obesity, and diabetes.


Research: Complication of Diabetes and Obesity


Expertise:

  • Neurodegenerative Disorders Research
  • Neuroimaging (in vivo) Research
Past Affiliations

Senior Associate Consultant, Department of Neuroscience, Mayo Clinic (past)

Assistant Professor, Department of Neurology, School of Medicine, Washington University in St. Louis (past)

Hope Center for Neurological Disorders, Department of Neurology, School of Medicine, Washington University in St. Louis (past)

Professor, Department of Medical and Molecular Genetics, Indiana University School of Medicine

Member, Center for Diabetes and Metabolic Diseases, Centers and Institutes, Indiana University School of Medicine

Assistant Professor, Neurosciences, Division of Biology and Biomedical Sciences, School of Medicine, Washington University in St. Louis (past)

Molecular Cell Biology, Division of Biology and Biomedical Sciences, School of Medicine, Washington University in St. Louis (past)

Biochemistry, Division of Biology and Biomedical Sciences, School of Medicine, Washington University in St. Louis (past)

Communities
Human Genetics, Neuroscience, Biomedical Science
Degrees
PhD, Mayo Clinic College of Medicine, Molecular Neuroscience, 2007
BS, Pohang University of Science and Technology, Life Science, 2000
Keywords
transcriptomics quantitative genetics dementia alzheimers disease proteomics single cell biology