10 Publications
2018
LRRK2 deficiency impairs trans-Golgi to lysosome trafficking and endocytic cargo degradation in human renal proximal tubule epithelial cells
Lanning, Nathan James⋅VanOpstall, Calvin⋅Goodall, Megan L⋅MacKeigan, Jeffrey P and Looyenga, Brendan David
American journal of physiology. Renal physiology, vol. 315, (no. 5), pp. F1465-F1477, Nov 1, 2018. | Journal Article
2017
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
Mulcahy Levy, Jean M⋅Zahedi, Shadi⋅Griesinger, Andrea M⋅Morin, Andrew⋅Davies, Kurtis D⋅Aisner, Dara L⋅Kleinschmidt-DeMasters, B K⋅Fitzwalter, Brent E⋅Goodall, Megan L⋅Thorburn, Jacqueline⋅Amani, Vladimir⋅Donson, Andrew M⋅Birks, Diane K⋅Mirsky, David M⋅Hankinson, Todd C⋅Handler, Michael H⋅Green, Adam L⋅Vibhakar, Rajeev⋅Foreman, Nicholas K and Thorburn, Andrew
eLife, vol. 6, Jan 17, 2017. | Journal Article
 
Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells
Thorburn, Jacqueline⋅Staskiewicz, Leah⋅Goodall, Megan L⋅Dimberg, Lina⋅Frankel, Arthur E⋅Ford, Heide L and Thorburn, Andrew
Molecular pharmacology, vol. 91, (no. 1), pp. 58-64, Jan 2017. | Journal Article
2016
Autophagy complexes cell death by necroptosis
Goodall, Megan L⋅Cramer, Scott D and Thorburn, Andrew
Oncotarget, vol. 7, (no. 32), pp. 50818-50819, Aug 9, 2016. | Journal Article
 
Autophagy RIPs into cell death
Goodall, Megan L⋅Cramer, Scott D and Thorburn, Andrew
Cell Cycle, vol. 15, (no. 22), pp. 3014-3015, Nov 16, 2016. | Journal Article
 
The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis
Goodall, Megan L⋅Fitzwalter, Brent E⋅Zahedi, Shadi⋅Wu, Min⋅Rodriguez, Diego⋅Mulcahy-Levy, Jean M⋅Green, Douglas R⋅Morgan, Michael⋅Cramer, Scott D and Thorburn, Andrew
Developmental Cell, vol. 37, (no. 4), pp. 337-349, May 23, 2016. | Journal Article
2015
Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion
Maycotte, Paola⋅Maycotte, P.⋅Jones, K.L.⋅Jones, Kenneth L⋅Goodall, M.L.⋅Goodall, Megan L⋅Thorburn, Jacqueline⋅Thorburn, J.⋅Thorburn, A. and Thorburn, Andrew
Molecular cancer research : MCR, vol. 13, (no. 4), pp. 651-658, Apr 2015. | Journal Article
 
Synthesis of Improved Lysomotropic Autophagy Inhibitors
Wang, Tong⋅Goodall, Megan L⋅Gonzales, Paul⋅Sepulveda, Mario⋅Martin, Katie R⋅Gately, Stephen and MacKeigan, Jeffrey P
Journal of medicinal chemistry, vol. 58, (no. 7), pp. 3025-3035, Apr 9, 2015. | Journal Article
2014
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
Goodall, Megan L⋅Wang, Tong⋅Martin, Katie R⋅Kortus, Matthew G⋅Kauffman, Audra L⋅Trent, Jeffrey M⋅Gately, Stephen and MacKeigan, Jeffrey P
Autophagy, vol. 10, (no. 6), pp. 1120-1136, Jun 1, 2014. | Journal Article
 
Identifying specific receptors for cargo-mediated autophagy
Goodall, Megan and Thorburn, Andrew
Cell Research, vol. 24, (no. 7), pp. 783-784, 2014. | Journal Article