10 Publications
LRRK2 deficiency impairs trans-Golgi to lysosome trafficking and endocytic cargo degradation in human renal proximal tubule epithelial cells
Lanning, Nathan JamesVanOpstall, CalvinGoodall, Megan LMacKeigan, Jeffrey P and Looyenga, Brendan David
American journal of physiology. Renal physiology, vol. 315, (no. 5), pp. F1465-F1477, Nov 1, 2018. | Journal Article
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
Mulcahy Levy, Jean MZahedi, ShadiGriesinger, Andrea MMorin, AndrewDavies, Kurtis DAisner, Dara LKleinschmidt-DeMasters, B KFitzwalter, Brent EGoodall, Megan LThorburn, JacquelineAmani, VladimirDonson, Andrew MBirks, Diane KMirsky, David MHankinson, Todd CHandler, Michael HGreen, Adam LVibhakar, RajeevForeman, Nicholas K and Thorburn, Andrew
eLife, vol. 6, Jan 17, 2017. | Journal Article
Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells
Thorburn, JacquelineStaskiewicz, LeahGoodall, Megan LDimberg, LinaFrankel, Arthur EFord, Heide L and Thorburn, Andrew
Molecular pharmacology, vol. 91, (no. 1), pp. 58-64, Jan 2017. | Journal Article
Autophagy complexes cell death by necroptosis
Goodall, Megan LCramer, Scott D and Thorburn, Andrew
Oncotarget, vol. 7, (no. 32), pp. 50818-50819, Aug 9, 2016. | Journal Article
Autophagy RIPs into cell death
Goodall, Megan LCramer, Scott D and Thorburn, Andrew
Cell Cycle, vol. 15, (no. 22), pp. 3014-3015, Nov 16, 2016. | Journal Article
The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis
Goodall, Megan LFitzwalter, Brent EZahedi, ShadiWu, MinRodriguez, DiegoMulcahy-Levy, Jean MGreen, Douglas RMorgan, MichaelCramer, Scott D and Thorburn, Andrew
Developmental Cell, vol. 37, (no. 4), pp. 337-349, May 23, 2016. | Journal Article
Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion
Maycotte, PaolaMaycotte, P.Jones, K.L.Jones, Kenneth LGoodall, M.L.Goodall, Megan LThorburn, JacquelineThorburn, J.Thorburn, A. and Thorburn, Andrew
Molecular cancer research : MCR, vol. 13, (no. 4), pp. 651-658, Apr 2015. | Journal Article
Synthesis of Improved Lysomotropic Autophagy Inhibitors
Wang, TongGoodall, Megan LGonzales, PaulSepulveda, MarioMartin, Katie RGately, Stephen and MacKeigan, Jeffrey P
Journal of medicinal chemistry, vol. 58, (no. 7), pp. 3025-3035, Apr 9, 2015. | Journal Article
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
Goodall, Megan LWang, TongMartin, Katie RKortus, Matthew GKauffman, Audra LTrent, Jeffrey MGately, Stephen and MacKeigan, Jeffrey P
Autophagy, vol. 10, (no. 6), pp. 1120-1136, Jun 1, 2014. | Journal Article
Identifying specific receptors for cargo-mediated autophagy
Goodall, Megan and Thorburn, Andrew
Cell Research, vol. 24, (no. 7), pp. 783-784, 2014. | Journal Article