22 Publications
2010
Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts.
Taramino, Silvia⋅Teske, Brian⋅Oliaro Bosso, Simonetta⋅Bard, Martin and Balliano, Gianni
Biochimica et biophysica acta, vol. 1801, (no. 11), pp. 1232-7, 2010/Nov. | Journal Article
2008
A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus
Willger, Sven D⋅Puttikamonkul, Srisombat⋅Kim, Kwang-Hyung⋅Burritt, James B⋅Grahl, Nora⋅Metzler, Laurel J⋅Barbuch, Robert⋅Bard, Martin⋅Lawrence, Christopher⋅Cramer, Robert and Filler, Scott G
PLoS Pathogens, vol. 4, (no. 11), pp. e1000200, 2008. | Journal Article
 
Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae.
Teske, B⋅Taramino, S⋅Bhuiyan, M S⋅Kumaraswami, N S⋅Randall, Stephen⋅Barbuch, R⋅Eckstein, J⋅Balliano, Gianni and Bard, Martin
Biochimica et biophysica acta, vol. 1781, (no. 8), pp. 359-66, 2008/Aug. | Journal Article
2007
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
Hughes, Adam L⋅Powell, David W⋅Bard, Martin⋅Eckstein, James⋅Barbuch, Robert⋅Link, Andrew J and Espenshade, Peter J
Cell metabolism, vol. 5, (no. 2), pp. 143-9, 2007/Feb. | Journal Article
 
Synthetically Lethal Interactions Involving Loss of the Yeast ERG24: The Sterol C-14 Reductase Gene
Bhuiyan, M. S⋅Eckstein, James⋅Barbuch, Robert and Bard, Martin
Lipids, vol. 42, (no. 1), pp. 69-76, Feb 2007. | Journal Article
 
The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum
Nakayama, Hironobu⋅Tanabe, Koichi⋅Bard, Martin⋅Hodgson, Wesley⋅Wu, Sung⋅Takemori, Daiki⋅Aoyama, Toshihiro⋅Kumaraswami, N S⋅Metzler, Laurel⋅Takano, Yukie⋅Chibana, Hiroji and Niimi, Masakazu
The Journal of Antimicrobial Chemotherapy, vol. 60, (no. 6), pp. 1264-72, Dec 2007. | Journal Article
2006
Cumulative Mutations Affecting Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae Result in Synthetic Lethality That Is Suppressed by Alterations in Sphingolipid Profiles
Valachovic, Martin⋅Bareither, Bart M⋅Bhuiyan, MShah A⋅Eckstein, James⋅Barbuch, Robert⋅Balderes, Dina⋅Wilcox, Lisa⋅Sturley, Stephen L⋅Dickson, Robert C and Bard, Martin
Genetics, vol. 173, (no. 4), pp. 1893-1908, 2006. | Journal Article
 
Endoplasmic Reticulum-Associated Degradation Is Required for Cold Adaptation and Regulation of Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae
Loertscher, Jennifer⋅Larson, Lynnelle L⋅Matson, Clinton K⋅Parrish, Mark L⋅Felthauser, Alicia⋅Sturm, Aaron⋅Tachibana, Christine⋅Bard, Martin and Wright, Robin
Eukaryotic Cell, vol. 5, (no. 4), pp. 712-722, 2006. | Journal Article
2005
Sterol uptake in Candida glabrata: Rescue of sterol auxotrophic strains
Bard, Martin⋅Sturm, Aaron M⋅Pierson, Charles A⋅Brown, Shaleak⋅Rogers, Kristina M⋅Nabinger, Sarah⋅Eckstein, James⋅Barbuch, Robert⋅Lees, Norman D⋅Howell, Susan A and Hazen, Kevin C
Diagnostic Microbiology and Infectious Disease, vol. 52, (no. 4), pp. 285-293, 2005. | Journal Article
2004
A Mutation in Sphingolipid Synthesis Suppresses Defects in Yeast Ergosterol Metabolism
Valachovic, Martin⋅Wilcox, Lisa J⋅Sturley, Stephen L and Bard, Martin
Lipids, vol. 39, (no. 8), pp. 747-52, Aug 2004. | Journal Article
2002
Candida albicans Sterol C-14 Reductase, Encoded by the ERG24 Gene, as a Potential Antifungal Target Site
Jia, N.⋅Arthington-Skaggs, B.⋅Lee, W.⋅Pierson, CA⋅Lees, Norman D⋅Eckstein, J.⋅Barbuch, R. and Bard, Martin
Antimicrobial Agents & Chemotherapy, vol. 46, (no. 4), pp. 947-957, 2002. | Journal Article
 
Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis
Mo, C.⋅Valachovic, M.⋅Randall, Stephen K⋅Nickels, JT and Bard, Martin
Proceedings of the National Academy of Sciences, USA, vol. 99, (no. 15), pp. 9739-9744, 2002. | Journal Article
2001
The Candida albicans ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) is essential for growth.
Aaron, K E⋅Pierson, C A⋅Lees, Norman D and Bard, Martin
FEMS yeast research, vol. 1, (no. 2), pp. 93-101, 2001/Jul. | Journal Article
 
Transcriptional Regulation of the Two Sterol Esterification Genes in the Yeast Saccharomyces cerevisiae
Jensen-Pergakes, K.⋅Guo, Z.⋅Giattina, M.⋅Sturley, SL and Bard, Martin
Journal of Bacteriology, vol. 183, (no. 17), pp. 4950-4957, 2001. | Journal Article
1999
Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation
Gachotte, D.⋅Sen, SE⋅Eckstein, J.⋅Barbuch, R.⋅Krieger, M.⋅Ray, BD and Bard, Martin
Proceedings of the National Academy of Sciences, USA, vol. 96, (no. 22), pp. 12655-12660, 1999. | Journal Article
 
Transcriptional regulation of the squalene synthase gene (ERG9) in the yeast Saccharomyces cerevisiae.
Kennedy, Matthew A⋅Barbuch, R. and Bard, Martin
Biochimica et biophysica acta = International journal of biochemistry and biophysics., vol. 1445, (no. 1), pp. 110-122, 1999. | Journal Article
1998
Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae.
Daum, G⋅Lees, Norman D⋅Bard, Martin and Dickson, R
Yeast (Chichester, England), vol. 14, (no. 16), pp. 1471-510, 1998/Dec. | Journal Article
 
Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis
Gachotte, D.⋅Barbuch, R.⋅Gaylor, J.⋅Nickel, E. and Bard, Martin
Proceedings of the National Academy of Sciences, USA, vol. 95, (no. 23), pp. 13794-13799, 1998. | Journal Article
 
Sequencing, disruption, and characterization of the Candida albicans sterol methyltransferase (ERG6) gene: Drug susceptibility studies in erg6 mutants
Jensen-Pergakes, KL⋅Kennedy, Matthew A⋅Lees, Norman D⋅Barbuch, R.⋅Koegel, C. and Bard, Martin
Antimicrobial Agents & Chemotherapy, vol. 42, (no. 5), pp. 1160-1167, 1998. | Journal Article
1997
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme
Gachotte, D.⋅Pierson, CA⋅Lees, Norman D⋅Barbuch, R.⋅Koegel, C. and Bard, Martin
Proceedings of the National Academy of Sciences, USA, vol. 94, (no. 21), pp. 11173-11178, 1997. | Journal Article
1996
Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase.
Bard, Martin⋅Bruner, D A⋅Pierson, C A⋅Lees, Norman D⋅Biermann, B⋅Frye, L⋅Koegel, C and Barbuch, R
Proceedings of the National Academy of Sciences of the United States of America, vol. 93, (no. 1), pp. 186-90, 1996/Jan/9. | Journal Article
1993
Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans.
Bard, Martin⋅Lees, Norman D⋅Turi, T⋅Craft, D⋅Cofrin, L⋅Barbuch, R⋅Koegel, C and Loper, John C
Lipids, vol. 28, (no. 11), pp. 963-7, 1993/Nov. | Journal Article