The focus of Dr. Scott’s basic research is the development of simple and inexpensive equipment and combinatorial synthetic methodologies to quickly make large numbers of “drug-like” molecules that facilitate the Distributed Drug Discovery project. These compounds can be screened in biological assays to generate leads for drug discovery. His synthetic focus is on the solid-phase synthesis of conformationally constrained peptidomimetic molecules, other general classes of biomimetic molecules, and unnatural amino acids.
