18 Publications
2012
P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells.
Hwang, Melissa⋅Hwang, Melissa⋅Peddibhotla, Sirisha⋅Peddibhotla, Sirisha⋅McHenry, Peter⋅McHenry, Peter⋅Chang, Peggy⋅Chang, Peggy⋅Yochum, Zachary⋅Yochum, Zachary⋅Park, Ko U⋅Park, Ko Un⋅Sears, James Cooper⋅Sears, James C⋅Vargo-Gogola, Tracy C and Vargo Gogola, Tracy
Cancers, vol. 4, (no. 2), pp. 475-89, 2012/Jun. | Journal Article
2011
P190A RhoGAP is required for mammary gland development.
Heckman-Stoddard, B M⋅Vargo-Gogola, Tracy C⋅Herrick, M P⋅Visbal, A P⋅Lewis, Michael T⋅Settleman, J and Rosen, Jeffrey M
Developmental biology, vol. 360, (no. 1), pp. 1-10, 2011/Dec/1. | Journal Article
2010
Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA.
Lynch, Conor⋅Lynch, Conor C⋅Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅Matrisian, Lynn M⋅Matrisian, Lynn M⋅Fingleton, Barbara and Fingleton, Barbara
Journal of oncology, vol. 2010, pp. 530745, 2010. | Journal Article
 
P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis.
McHenry, Peter R⋅McHenry, Peter R⋅Sears, James C⋅Sears, James C⋅Herrick, Matthew P⋅Herrick, Matthew P⋅Chang, Peggy⋅Chang, Peggy⋅Heckman-Stoddard, Brandy M⋅Heckman-Stoddard, Brandy M⋅Rybarczyk, Megan⋅Rybarczyk, Megan⋅Chodosh, Lewis A⋅Chodosh, Lewis A⋅Gunther, Edward J⋅Gunther, Edward J⋅Hilsenbeck, Susan G⋅Hilsenbeck, Susan G⋅Rosen, Jeffrey M⋅Rosen, Jeffrey M⋅Vargo-Gogola, Tracy C and Vargo Gogola, Tracy
Breast cancer research : BCR, vol. 12, (no. 5), pp. R73, 2010. | Journal Article
 
Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?
McHenry, P R and Vargo-Gogola, Tracy C
Current drug targets, vol. 11, (no. 9), pp. 1043-58, 2010/Sep. | Journal Article
 
Putting the brakes on breast cancer: therapeutic opportunities to bring cancer stem cells and the tumor microenvironment to a screeching halt.
Vargo-Gogola, Tracy C
Current drug targets, vol. 11, (no. 9), pp. 1041-2, 2010/Sep. | Journal Article
2009
Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.
Heckman-Stoddard, Brandy M⋅Heckman-Stoddard, Brandy M⋅Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅McHenry, Peter R⋅McHenry, Peter R⋅Jiang, Vivian⋅Jiang, Vivian⋅Herrick, Matthew P⋅Herrick, Matthew P⋅Hilsenbeck, Susan G⋅Hilsenbeck, Susan G⋅Settleman, Jeffrey⋅Settleman, Jeffrey⋅Rosen, Jeffrey M and Rosen, Jeffrey M
Breast cancer research : BCR, vol. 11, (no. 4), pp. R61, 2009. | Journal Article
2007
Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.
Heckman, Brandy M⋅Heckman, Brandy M⋅Chakravarty, Geetika⋅Chakravarty, Geetika⋅Vargo-Gogola, Tracy C⋅Vargo Gogola, Tracy⋅Gonzales-Rimbau, Maria⋅Gonzales-Rimbau, Maria⋅Hadsell, Darryl L⋅Hadsell, Darryl L⋅Lee, Adrian V⋅Lee, Adrian V⋅Settleman, Jeffrey⋅Settleman, Jeffrey⋅Rosen, Jeffrey M and Rosen, Jeffrey M
Developmental biology, vol. 309, (no. 1), pp. 137-49, 2007/Sep/1. | Journal Article
 
Matrix Metalloproteinase 7 Mediates Mammary Epithelial Cell Tumorigenesis through the ErbB4 Receptor
Lynch, Conor C⋅Lynch, Conor⋅Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅Martin, Michelle D⋅Martin, Michelle⋅Fingleton, Barbara⋅Fingleton, Barbara⋅Crawford, Howard⋅Crawford, Howard⋅Matrisian, Lynn M and Matrisian, Lynn
Cancer Research, vol. 67, (no. 14), pp. 6760-6767, 2007. | Journal Article
 
Modelling breast cancer: one size does not fit all
Vargo Gogola, Tracy⋅Rosen, Jeffrey M⋅Vargo-Gogola, Tracy and Rosen, Jeffrey M
Nature Reviews. Cancer, vol. 7, (no. 9), pp. 659-72, Sep 2007. | Journal Article
2006
P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland.
Vargo-Gogola, Tracy C⋅Vargo Gogola, Tracy⋅Heckman, Brandy M⋅Heckman, Brandy M⋅Gunther, Edward J⋅Gunther, Edward J⋅Chodosh, Lewis A⋅Chodosh, Lewis A⋅Rosen, Jeffrey M and Rosen, Jeffrey M
Molecular endocrinology (Baltimore, Md.), vol. 20, (no. 6), pp. 1391-405, 2006/Jun. | Journal Article
2005
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL
Lynch, Conor C⋅Lynch, Conor C⋅Hikosaka, Atsuya⋅Hikosaka, Atsuya⋅Acuff, Heath B⋅Acuff, Heath B⋅Martin, Michelle D⋅Martin, Michelle D⋅Kawai, Noriyasu⋅Kawai, Noriyasu⋅Singh, Rakesh K⋅Singh, Rakesh K⋅Vargo Gogola, Tracy C⋅Vargo-Gogola, Tracy C⋅Begtrup, Jennifer L⋅Begtrup, Jennifer L⋅Peterson, Todd E⋅Peterson, Todd E⋅Fingleton, Barbara⋅Fingleton, Barbara⋅Shirai, Tomoyuki⋅Shirai, Tomoyuki⋅Matrisian, Lynn M⋅Matrisian, Lynn M⋅Futakuchi, Mitsuru and Futakuchi, Mitsuru
Cancer Cell, vol. 7, (no. 5), pp. 485-496, 2005. | Journal Article
 
Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model
Xian, Wa⋅Xian, Wa⋅Schwertfeger, Kathryn L⋅Schwertfeger, Kathryn⋅Vargo-Gogola, Tracy⋅Vargo Gogola, Tracy⋅Rosen, Jeffrey M and Rosen, Jeffrey
The Journal of Cell Biology, vol. 171, (no. 4), pp. 663-673, Nov 21, 2005. | Journal Article
2002
Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand.
Vargo-Gogola, Tracy C⋅Vargo Gogola, Tracy⋅Crawford, Howard C⋅Crawford, Howard⋅Fingleton, Barbara⋅Fingleton, Barbara⋅Matrisian, Lynn M and Matrisian, Lynn M
Archives of biochemistry and biophysics, vol. 408, (no. 2), pp. 155-61, 2002/Dec/15. | Journal Article
 
Matrilysin (matrix metalloproteinase-7) selects for apoptosis-resistant mammary cells in vivo.
Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅Fingleton, Barbara⋅Fingleton, Barbara⋅Crawford, Howard⋅Crawford, Howard⋅Matrisian, Lynn and Matrisian, Lynn M
Cancer Research, vol. 62, (no. 19), pp. 5559-63, 2002/Oct/1. | Journal Article
 
The mechanisms by which matrix metalloproteinase-7 promotes mammary tumorigenesis (Dissertation)
Vargo-Gogola, Tracy (2002).
2001
Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis.
Fingleton, Barbara⋅Fingleton, Barbara⋅Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅Crawford, Howard⋅Crawford, Howard C⋅Matrisian, Lynn M and Matrisian, Lynn M
Neoplasia (New York, N.Y.), vol. 3, (no. 6), pp. 459-68, 2001 Nov-Dec. | Journal Article
1998
Direct evidence for rapid degradation of Bacillus thuringiensis toxin mRNA as a cause of poor expression in plants.
De Rocher, E.J.⋅De Rocher, E.⋅Vargo Gogola, Tracy⋅Vargo-Gogola, Tracy C⋅Diehn, S.H.⋅Diehn, Scott⋅Green, Pamela J and Green, Pamela
Plant physiology., vol. 117, (no. 4), pp. 1445-1461, 1998. | Journal Article