My research focuses on investigating the following:
- the role of the functional blood-brain barrier (BBB) in maintaining brain function and homeostasis
- the role of the vasculature in clearing brain waste products like amyloid-β
- the neurovascular unit that works in concert to maintain a healthy brain
- targeting the BBB as a preventive and therapeutic approach for AD and CAA
- discovery and development of drugs that target brain vasculature dysfunction in AD and CAA
Research:
My research focuses on investigating the following:
- the role of the functional blood-brain barrier (BBB) in maintaining brain function and homeostasis
- the role of the vasculature in clearing brain waste products like amyloid-β
- the neurovascular unit that works in concert to maintain a healthy brain
- targeting the BBB as a preventive and therapeutic approach for AD and CAA
- discovery and development of drugs that target brain vasculature dysfunction in AD and CAA
Research:
- Role of the blood-brain barrier (BBB) in the pathogenesis of Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA)
- Drug discovery and development for Alzheimer’s disease and related dementias
- Extra-virgin olive oil (EVOO) as medical
- Pharmacokinetic and pharmacokinetics in silico modeling
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