Expertise

The research of ANEL focuses on nano-biotechnology, where we use materials as the central core and build around with nanotechnology and microsystems in surface patterning, self assembly, micromachining and advanced optics to push forward the frontiers in Biosensing, Medicine/NanoEHS, Biophysics and Immunology. Specifically, we are seeking solutions allowing ultrasensitive protein biomarker detection for early disease screening and diagnosis. We are interested in multi-parametric cellular functional analysis of immune cells using optofluidics biosensors for future medicine and nano environmental health and safety. In addition, we would like to develop nanoplasmonic biosensors for mapping single cell secretion and cell-to-cell communication to gain a deeper understanding in biology and immunology.

Chen's research interests focus on advancing nanotechnology and microsystems in surface patterning, self-assembly, micromachining and optics to push forward the frontiers in Biosensing, Medicine/NanoEHS, Biophysics and Immunology.

Research:

  • Ultrasensitive Biomarker Detection for Precision Medicine and Early Disease Screening
  • Multi-parametric immunoanalysis for Personalized Immune Therapy and NanoEHS 
  • Real-time Mapping Cytokine Secretion for Single Cell Immunoanalysis

Research Interests:

  • Advancing nanomaterial based optofluidic biosensors for biomarker detection, enviromental sensing, and precision medicine.
  • Extrapolating the biological fate of nanoparticles (NPs) by evaluating the unknown interactions of NPs and proteins to understand the transformation of NPs by ligands in biological systems.
  • Real-time mapping cytokine secretion for single cell immunoanalysis, cell-to-cell communication.

Subject Areas:

  • Nanomaterials
  • Biosensors
  • Precision Medicine
  • Food Safety
  • Biophysics

Research Areas:

Nanoplasmonic Biosensors
Single-cell Analysis
Precision Medicine
Protein-nanomaterial Interaction
Food and Environmental Safety

Communities
Mechanical Engineering
Degrees
PhD, Clemson University, Materials Science and Engineering, 2012
MS, Clemson University, Materials Science and Engineering, 2009
BS, Nanjing University, Nanjing, China, Materials Science and Engineering, 2006