My research focuses on investigating the following:

  • the role of the functional blood-brain barrier (BBB) in maintaining brain function and homeostasis
  • the role of the vasculature in clearing brain waste products like amyloid-β
  • the neurovascular unit that works in concert to maintain a healthy brain
  • targeting the BBB as a preventive and therapeutic approach for AD and CAA
  • discovery and development of drugs that target brain vasculature dysfunction in AD and CAA


  • Role of the blood-brain barrier (BBB) in the pathogenesis of Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA)
  • Drug discovery and development for Alzheimer’s disease and related dementias
  • Extra-virgin olive oil (EVOO) as medical
  • Pharmacokinetic and pharmacokinetics in silico modeling
PhD, Nagasaki University, Japan, Pharmaceutical Sciences, 2004
MS, Nagasaki University, Japan, Pharmaceutical Sciences, 2001
BSc, Kuwait University, Biochemistry , 1985
cerebral amyloid angiopathy olive oil blood-brain barrier alzheimers disease