147 Publications (Page 6 of 6)
2009
Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patientsBulitta, Juergen B⋅Bulitta, Juergen B.⋅Zhao, Ping⋅Zhao, Ping⋅Arnold, Robert D⋅Arnold, Robert D.⋅Kessler, Dean R⋅Kessler, Dean R.⋅Daifuku, Richard⋅Daifuku, Richard⋅Pratt, James⋅Pratt, James⋅Luciano, Gabriel⋅Luciano, Gabriel⋅Hanauske, Axel-R⋅Hanauske, Axel-R.⋅Gelderblom, Hans⋅Gelderblom, Hans⋅Awada, Ahmad⋅Awada, Ahmad⋅Jusko, William J. and Jusko, WilliamCancer Chemotherapy and Pharmacology, vol. 63, (no. 6), pp. 1035-1048, 2009.
| Journal Article
2007
A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancerO’Connor, R.⋅O’Leary, M.⋅Ballot, J.⋅Collins, C.D.⋅Kinsella, P.⋅Mager, D.E.⋅Arnold, R.D.⋅O’Driscoll, L.⋅Larkin, A.⋅Kennedy, S.⋅Fennelly, D.⋅Clynes, M. and Crown, J.Cancer Chemotherapy and Pharmacology, vol. 59, pp. 79-87.
| Journal Article
Biotechnology-Derived Drug Product DevelopmentCarl, S.M.⋅Lindley, D.J.⋅Knipp, G.T.⋅Morris, K.R.⋅Oliver, E.⋅Becker, G.W. and Arnold, R.D.2007
2006
A Phase 1 clinical and pharmacokinetic study of the Multidrug Resistance Protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancerO'Conner, R⋅O'Leary, M.O., Ballot, R., Collins, C., Kinsella, P., Mager, D.M., Arnold, R.D., O'Driscoll, L.O., Larkin, A.M., Kennedy, S., Fennelly, D., Clynes, M., and Crown, J. and Arnold, Robert DCancer Chemotherapy and Pharmacology, 2006.
| Journal Article
2005
Effect of repetitive administration of doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistributionArnold, Robert D⋅Mager, D.E.⋅Slack, J.E. and Straubinger, R.MClinical Cancer Research, 2005.
| Journal Article
Effect of Repetitive Administration of Doxorubicin-Containing Liposomes on Plasma Pharmacokinetics and Drug Biodistribution in a Rat Brain Tumor ModelArnold, Robert⋅Arnold, Robert D⋅Mager, Donald⋅Mager, Donald E⋅Slack, Jeanine E⋅Slack, Jeanine⋅Straubinger, Robert and Straubinger, Robert MClinical Cancer Research, vol. 11, (no. 24), pp. 8865, 20051215.
| Journal Article
Effect of Repetitive Administration of Doxorubicin-Containing Liposomes on Plasma Pharmacokinetics and Drug Biodistribution in a Rat Brain Tumor ModelArnold, Robert⋅Arnold, Robert D⋅Mager, Donald⋅Mager, Donald E⋅Slack, Jeanine E⋅Slack, Jeanine⋅Straubinger, Robert and Straubinger, Robert MClinical Cancer Research, vol. 11, (no. 24), pp. 8856-8865, 2005.
| Journal Article
Tumor antivascular effects of sterically-stabilized doxorubicin-containing liposomesArnold, R.D.,⋅Mager, D.E., Spernyak, J.A., Mazurchuk, R.V., Straubinger, R. and Arnold, Robert DAACR National Meeting, Anaheim, CA.. 2005.
| Conference Proceeding
2004
Altered plasma pharmacokinetics, tumor/tissue biodistribution, and barrier properties of the tumor microvasculature in rats following repetitive dosing of doxorubicin liposomesArnold, R.D.,⋅Slack, J.E., Mager, D.E., R., Spernyak, J., Mazurchuk, R., Straubinger, R. and Arnold, Robert DAdvances in Liposomes: New Technologies and New Therapies, Chicago, IL. 2004.
| Conference Proceeding
Antivascular and antitumor activities of liposome-associated drugsStraubinger RM⋅Arnold, Robert D⋅Zhou R⋅Mazurchuk R and Slack JEAnticancer Research, vol. 24, (no. 2A), pp. 397-404, Mar-Apr 2004.
| Journal Article
Antivascular and antitumor activities of liposome-associated drugs.Straubinger, Robert M⋅Arnold, Robert D⋅Zhou, Rong⋅Mazurchuk, Richard and Slack, Jeanine EAnticancer research, vol. 24, (no. 2A), pp. 397-404, 2004 Mar-Apr.
| Journal Article
Antivascular and Antitumor Activities of Liposome-associated DrugsStraubinger, Robert M⋅Arnold, Robert D⋅Zhou, R.⋅Mazurchuk, R. and Slack, JEAnticancer Research, vol. 24, (no. 2A), pp. 397-404, 2004.
| Journal Article
Effect of repetitive administration of doxorubicin encapsulated in sterically stabilized liposomes on plasma kinetics, brain tumor/tissue drug deposition, and tumor vascular permeability in RatsArnold, R.D.,⋅Slack, J.E., Mager, D.E., and Straubinger R.M. and Arnold, Robert DAACR National Meeting, Orlando, FL. 2004.
| Conference Proceeding
Increased brain tumor deposition of doxorubicin liposomes following repetitive dosing: alterations in plasma pharmacokinetics and barrier properties of the tumor microvasculature in ratsArnold, R.D.,⋅Slack, J.E., Mager, D.E., and Straubinger, R., and Arnold, Robert DAAPS National Meeting, Baltimore, MD. 2004.
| Conference Proceeding
Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopyArnold, Robert D⋅Arnold, Robert D⋅Slack, Jeanine E⋅Slack, Jeanine E⋅Straubinger, Robert M and Straubinger, Robert MJournal of Chromatography B, vol. 808, (no. 2), pp. 152, 2004.
| Journal Article
Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy.Arnold, Robert D⋅Arnold, Robert D⋅Slack, Jeanine E⋅Slack, Jeanine E⋅Straubinger, Robert M and Straubinger, Robert MJournal of chromatography. B, Analytical technologies in the biomedical and life sciences, vol. 808, (no. 2), pp. 141-52, 2004/Sep/5.
| Journal Article
Tumor antivascular effects of liposome-incorporated drugs (Dissertation)Arnold, Robert D (2004).
Tumor Antivascular Effects of Liposome-Incorporated DrugsArnold, Robert DSpring 2004
2003
Analysis of doxorubicin in rat tissues by liquid chromatography tandem mass spectroscopy (LC-MS/MS)Arnold, R.D.,⋅Slack, J.E., and Straubinger R.M. and Arnold, Robert DAAPS National Meeting, Salt Lake City, UT. 2003.
| Conference Proceeding
Antivascular effect of doxorubicin liposomes in a rat brain tumor modelArnold, R.D.,⋅Slack, J.E., Zhou, R., Mazurchuk, Chau, R.I., and Straubinger R.M. and Arnold, Robert DAAPS National Meeting, Salt Lake City, UT. 2003.
| Conference Proceeding
n.d.no date or unknown
Enhanced tumor vascular permeability with repetitive administration of doxorubicin-containing liposomes in a rat brain tumor modelArnold, Robert D and Slack, J.E., and Straubinger R.M..
| Journal Article
Liposomal formulation of TNP-470 and plasma stabilityArnold, R.D., Balasubramanian, S., Straubinger, R.M and Arnold, Robert D.
| Journal Article