Expertise

Specifically, his laboratory is focused on developing and optimizing dosing schedules and novel composite lipid-nanoparticles as drug carriers. His research aims to gain insights into how dosing schedules and nanomedicines can be used to improve drug delivery, modulate drug exposure profiles, and improve drug treatment.

Research:

  • Development of Nanomedicines for Treatment of Prostate Cancer and Tumor Imaging
  • Experimental Therapeutics (PK) and Dose Optimization
  • CNS Disorders, Drug Toxicity and Treatment

The focus of his research is the development and utilization of nanomedicines and alternate dosing schedules to improve the treatment of cancers. Specifically, he is interested in developing composite nanomedicines to improve drug delivery to primary tumors and metastatic disease and utilizing pharmacokinetic–pharmacodynamics (PK/PD) modeling and simulation to optimize drug dosing schedules.


Research focuses on determining the effect of alternate dosing schedules and developing targeted nanomedicines to improve detection of disease and improve drug delivery and antitumor efficacy.

Affiliations

Professor, Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University
2018

Senior Scientist, Experimental Therapeutics, UAB O'Neal Comprehensive Cancer Center

Past Affiliations

Adjunct Professor, Department of Pathobiology, College of Veterinary Medicine, Auburn University

Adjunct Professor, Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia (past)

Assistant Professor, Pharmaceutical and Biomedical Sciences

Postdoctoral Fellow, Small Animal Imaging Facility

Associate Member, Center for Drug Discovery, University of Georgia (past)

Scientist, Liquid and Parenteral Formulations Research

Postdoctoral Fellow, Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York at Buffalo (past)

Associate Member, Biomedical Health Sciences Institute, University of Georgia (past)

Associate Member, Georgia Cancer Center, University of Georgia (past)

Associate Professor, Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University

Communities
Veterinary Medicine, Pharmacy
Degrees
PhD, University at Buffalo, Pharmaceutical Sciences, 2004
BS, State University of New York College at Plattsburgh, Biochemistry, 1994
Keywords
pharmacy & pharmacology cancer or carcinogenesis pharmaceuticals drug delivery systems pharmacokinetics antineoplastic agents chemotherapy methods of drug delivery nanotechnology nanomedicine nanoparticles preclinical translational studies pk/pd
Languages
English
Honors

Teacher of the Year Award, University of Georgia, College of Pharmacy, 2011

Induction into Rho Chi Society, Academic Honors Society of Pharmacy, 2009

Distinguished Cancer Scholar, Georgia Cancer Coaltion, 2007

First Prize - Poster Competition, Alteration in Pharmacokinetics, Drug Biodistribution, and Tumor Vascular Permeability after Repetitive Treatment with Doxorubicin Liposomes in Rats, The 7th Annual Regional Cancer Center Consortium for Biological Treatment of Cancer (Roswell Park Cancer Institute), 2004

Presenter - Graduate Student Symposium in Drug Delivery and Pharmaceutical Sciences, American Association of Pharmaceutical Scientists (AAPS National Meeting in Salt Lake City, Utah), 2003-2003

Best Platform Presentation Award, Modulation of Tumor Vascular Permeability by Doxorubicin Liposomes, University at Buffalo - Roswell Park Drug Research Symposium, 2003

Pharmaceutical Sciences Graduate Scholar Award, Department of Pharmaceutical Sciences (University at Buffalo), 2002-2002

Outstanding Graduate Student Poster Award, Reversed-Phase LC-MS/MS Assay for TNP-470, Sigma Xi, 2002

Fellow - AFPE, American Foundation for Pharmaceutical Education, 1999-2002

Associations
American Association for Cancer Research
American Association for the Advancement of Science
American Association of Colleges of Pharmacy
American Association of Pharmaceutical Scientists
International Liposome Society