54 Publications (Page 1 of 3)
2021
Designing new antitubercular isoniazid derivatives with improved reactivity and membrane trafficking abilities.
de Faria, Catarina Frazão⋅Moreira, Tânia⋅Lopes, Pedro⋅Costa, Henrique⋅Krewall, Jessica R⋅Barton, Callie M⋅Santos, Susana⋅Goodwin, Douglas⋅Machado, Diana⋅Viveiros, Miguel⋅Machuqueiro, Miguel and Martins, Filomena
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, vol. 144, pp. 112362, October 25, 2021. | Journal Article
2018
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, Mansour S⋅Alturki, M.S.⋅Fuanta, Ngolui Rene⋅Fuanta, N.R.⋅Jarrard, Madison A⋅Jarrard, M.A.⋅Hobrath, Judith V⋅Hobrath, J.V.⋅Goodwin, Douglas C⋅Goodwin, D.C.⋅Rants'o, Thankhoe A⋅Rants’o, T.A.⋅Calderón, Angela I and Calderón, A.I.
Bioorganic & Medicinal Chemistry Letters, vol. 28, (no. 4), pp. 808, 2018-02-15. | Journal Article
 
Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone.
Simithy, Johayra⋅Simithy, J.⋅Fuanta, N.R.⋅Fuanta, Ngolui Rene⋅Hobrath, J.V.⋅Hobrath, Judith V⋅Kochanowska-Karamyan, A.⋅Kochanowska-Karamyan, Anna⋅Hamann, Mark T⋅Hamann, M.T.⋅Goodwin, D.C.⋅Goodwin, Douglas C⋅Calderón, A.I. and Calderón, Angela I
Biochimica et biophysica acta, vol. 1866, (no. 5-6), pp. 731-739. | Journal Article
 
Slow-Binding Inhibition of Mycobacterium tuberculosis Shikimate Kinase by Manzamine Alkaloids.
Simithy, J.⋅Simithy, Johayra⋅Fuanta, N.R.⋅Fuanta, Ngolui Rene⋅Alturki, M.⋅Alturki, Mansour⋅Hobrath, J.V.⋅Hobrath, Judith V⋅Wahba, A.E.⋅Wahba, Amir E⋅Pina, I.⋅Pina, Ivett⋅Rath, Jnanendra⋅Rath, J.⋅Hamann, Mark T⋅Hamann, M.T.⋅DeRuiter, Jack⋅Deruiter, J.⋅Goodwin, D.C.⋅Goodwin, Douglas C⋅Calderón, Angela I and Calderón, A.I.
Biochemistry, July 31, 2018. | Journal Article
2017
A multifaceted approach to identify non-specific enzyme inhibition:Application to Mycobacterium tuberculosis shikimate kinase
Alturki, Mansour⋅Fuanta, Ngolui⋅Jarrard, Madison⋅Hobrath, Judith⋅Goodwin, Douglas⋅Rants'o, Thankhoe and Calderón, Angela
2017-12-05. | Journal Article
 
Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron hole-hopping within the enzyme
Njuma, Olive J⋅Njuma, Olive J⋅Davis, Ian⋅Davis, Ian⋅Ndontsa, Elizabeth N⋅Ndontsa, Elizabeth N⋅Krewall, Jessica R⋅Krewall, Jessica R⋅Liu, Aimin⋅Liu, Aimin⋅Goodwin, Douglas C and Goodwin, Douglas C
The Journal of biological chemistry, vol. 292, (no. 45), pp. 18421, 2017-11-10. | Journal Article
2015
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity.
Kudalkar, Shalley N⋅Njuma, Olive J⋅Li, Yongjiang⋅Muldowney, Michelle⋅Fuanta, N Rene and Goodwin, Douglas C
Biochemistry, vol. 54, (no. 8), pp. 1648-1662, March 3, 2015. | Journal Article
 
Development of an ESI-LC-MS-based assay for kinetic evaluation of Mycobacterium tuberculosis shikimate kinase activity and inhibition.
Simithy, Johayra⋅Simithy, J.⋅Gill, G.⋅Gill, Gobind⋅Wang, Yu⋅Wang, Y.⋅Goodwin, D.C.⋅Goodwin, Douglas C⋅Calderón, Angela I and Calderón, A.I.
Analytical chemistry, vol. 87, (no. 4), pp. 2129-2136, February 17, 2015. | Journal Article
 
Inactivation of myeloperoxidase by benzoic acid hydrazide
Huang, Jiansheng⋅Huang, Jiansheng⋅Huang, Jiansheng⋅Smith, Forrest⋅Smith, Forrest⋅Smith, Forrest⋅Panizzi, Peter⋅Panizzi, Jennifer R.⋅Panizzi, Jennifer R⋅Panizzi, Jennifer R⋅Panizzi, Peter⋅Goodwin, Douglas C⋅Goodwin, Douglas C.⋅Goodwin, Douglas C and Panizzi, Peter
Archives of Biochemistry and Biophysics, vol. 570, pp. 14--22. | Journal Article
 
Plasmodium falciparum Thioredoxin Reductase (PfTrxR) and Its Role as a Target for New Antimalarial Discovery.
McCarty, Sara E⋅McCarty, S.E.⋅Schellenberger, A.⋅Schellenberger, Amanda⋅Goodwin, Douglas C⋅Goodwin, D.C.⋅Fuanta, Ngolui Rene⋅Fuanta, N.R.⋅Tekwani, Babu L⋅Tekwani, B.L.⋅Calderón, A.I. and Calderón, Angela I
Molecules (Basel, Switzerland), vol. 20, (no. 6), pp. 11459-11473, 2015. | Journal Article
 
Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials.
Gordon, Sara⋅Gordon, S.⋅Simithy, J.⋅Simithy, Johayra⋅Goodwin, D.C.⋅Goodwin, Douglas C⋅Calderón, Angela I and Calderón, A.I.
Perspectives in medicinal chemistry, vol. 7, pp. 9-20, 2015. | Journal Article
2014
Catalase in peroxidase clothing: Interdependent cooperation of two cofactors in the catalytic versatility of KatG.
Njuma, Olive J⋅Ndontsa, Elizabeth N and Goodwin, Douglas C
Archives of biochemistry and biophysics, vol. 544, pp. 27-39, February 15, 2014. | Journal Article
2013
From Contrastive Rhetoric towards Perceptions of Identity: Written Academic English in Central Mexico
Crawford, Troy⋅Mora Pablo, Irasema⋅Goodwin, Douglas and Lengelin, Martha
Colombian Applied Linguistics Journal, vol. 15, (no. 1), pp. 24, 20130601. | Journal Article
 
Integral role of the I'-helix in the function of the "inactive" C-terminal domain of catalase-peroxidase (KatG).
Wang, Yu and Goodwin, Douglas
Biochimica et biophysica acta, vol. 1834, (no. 1), pp. 362-71, 2013/Jan. | Journal Article
2012
Bone Dielectric Property Variation as a Function of Mineralization at Microwave Frequencies
Meaney, Paul M⋅Meaney, Paul⋅Zhou, Tian⋅Zhou, Tian⋅Goodwin, Douglas⋅Goodwin, Douglas⋅Golnabi, Amir⋅Golnabi, Amir⋅Attardo, Elia⋅Attardo, Elia A⋅Paulsen, Keith D and Paulsen, Keith
International journal of biomedical imaging, vol. 2012, pp. 9, 2012. | Journal Article
 
Enhancing the peroxidatic activity of KatG by deletion mutagenesis.
Kudalkar, Shalley N⋅Campbell, Robert A⋅Li, Yongjiang⋅Varnado, Cornelius L⋅Prescott, Corey and Goodwin, Douglas
Journal of inorganic biochemistry, vol. 116, pp. 106-15, 2012/Nov. | Journal Article
 
Stimulation of KatG catalase activity by peroxidatic electron donors.
Ndontsa, Elizabeth N⋅Moore, Robert L and Goodwin, Douglas
Archives of biochemistry and biophysics, vol. 525, (no. 2), pp. 215-22, 2012/Sep/15. | Journal Article
2011
An Improvised Mechanism for H2O2 Disproportionation Based on an Old Enzyme Scaffold
Ndontsa, Elizabeth N and Goodwin, Douglas C
Free Radical Biology and Medicine, vol. 51, pp. S148, 2011-11-00. | Journal Article
 
Contribution of An “Inactive” Domain To Rapid H2O2Decomposition by KatG
Wang, Yu and Goodwin, Douglas
Free Radical Biology and Medicine, vol. 51, pp. S151, 2011-11-00. | Journal Article
 
Essential Role of Distant Interdomain Interactions in H2O2 Decomposition by Catalase-Peroxidases
Duan, Haijun and Goodwin, Douglas C
Free Radical Biology and Medicine, vol. 51, pp. S144, 2011-11-00. | Journal Article
 
Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase.
Tejero, Jesús⋅Tejero Bravo, Jesus⋅Biswas, Ashis⋅Haque, Mohammad M⋅Wang, Zhi Qiang⋅Hemann, Craig⋅Varnado, Cornelius L⋅Novince, Zachary⋅Hille, Charles Russell⋅Goodwin, Douglas and Stuehr, Dennis J
The Biochemical journal, vol. 433, (no. 1), pp. 163-74, 2011/Jan/1. | Journal Article
 
Students and Teachers' Reasons for Using the First Language Within the Foreign Language Classroom (French and English) in Central Mexico
Mora Pablo, Irasema⋅Lengeling, M. Martha⋅Rubio Zenil, Buenaventura⋅Crawford, Troy and Goodwin, Douglas
Profile Issues in Teachers` Professional Development, vol. 13, (no. 2), pp. 129, 20111001. | Journal Article
 
Students and teachers' reasons for using the first language within the foreign language classroom (French and English) in Central Mexico/Razones de alumnos y maestros sobre el uso de la primera lengua en el salon de lenguas extranjeras en el centro de Mexico
Pablo, Irasema⋅Lengeling, M.⋅Zenil, Buenaventura⋅Crawford, Troy and Goodwin, Douglas
Revista PROFILE Issues in Teachers' Professional Development, vol. 13, (no. 2), pp. 113, 20111001. | Journal Article
2008
Substitution of strictly conserved Y111 in catalase-peroxidases: Impact of remote interdomain contacts on active site structure and catalytic performance.
Moore, Robert L⋅Cook, Carma O⋅Williams, Rachel and Goodwin, Douglas
Journal of inorganic biochemistry, vol. 102, (no. 9), pp. 1819-24, 2008/Sep. | Journal Article
 
The kinetic properties producing the perfunctory pH profiles of catalase-peroxidases.
Moore, Robert L⋅Powell, Luke J and Goodwin, Douglas
Biochimica et biophysica acta, vol. 1784, (no. 6), pp. 900-7, 2008/Jun. | Journal Article