Expertise

We study the Epidermal Growth Factor (EGF) family of peptide hormones and their receptors, the ErbB receptor tyrosine kinases. This network regulates the proliferation and differentiation of epithelial cells and deregulated signaling by this network contributes to human tumorigenesis and increased tumor cell invasiveness, metastatic potential, and chemoresistance. Consequently, we seek to understand the mechanism by which this network regulates cell function, with the ultimate goal being the development of novel cancer treatments.

Past Affiliations

Associate Dean, Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University

Associate Professor, Purdue University Center for Cancer Research, Purdue University (past)

Associate Professor, Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University (past)

Associate Professor, Integrative Neuroscience Graduate Program, Graduate School, Purdue University (past)

Postdoctoral Training, Department of Pathology, Yale School of Medicine, Yale University (past)

Adjunct Professor, Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University (past)

Communities
Pharmacy
Degrees
PhD, Yale University, Genetics, 1993
MPhil, Yale University, Human Genetics, 1989
AB, Wabash College, Biology, 1987
Keywords
medical imaging medicinal chemistry cancer biology cancer or carcinogenesis breast cancer bioinstrumentation chemotherapeutic agents medical diagnosis growth factors growth factor receptors
Languages
English
Honors

President's Outstanding Collaborative Unit Award, Auburn University, October 2014

Outstanding Cancer Research Award, Purdue University Center for Cancer Research and Lafayette (IN) Lions Club, May 2010

Fellow, Academic Leadership Fellowship Program, American Association of Colleges of Pharmacy, 2011-2012

George Fulton Gilliland and Olga Hooser Gilliland Franklin Professorship, Auburn University Harrison School of Pharmacy, 2010-present

New Investigator Award (Prostate Cancer Research), US Army Medical Research and Materiel Command (Purdue University), 2002-2005

Career Development Award (Breast Cancer Research), US Army Medical Research and Materiel Command (Purdue University), 2000-2004

Outstanding Pharmacy Undergraduate Teaching Award (Medicinal Chemistry and Molecular Pharmacology), Purdue University School of Pharmacy, 2000

Postdoctoral Fellowship (Breast Cancer Research), US Army Medical Research and Materiel Command (Yale University), 1994-1997

Predoctoral Fellowship (Genetics), Howard Hughes Medical Institute (Yale University), 1988-1993

Associations
American Association for Cancer Research
American Association for the Advancement of Science
American Association of Colleges of Pharmacy
American Chemical Society
American Society for Biochemistry and Molecular Biology
American Society for Microbiology
Biochemical Society
Phi Beta Kappa
Sigma Xi, The Scientific Research Society