Much of our work focuses on the pathogenesis of betaherpeviruses, which includes the human pathogen Human Cytomegalovirus (HCMV).
Our interests lie in understanding host innate immune defenses and the mechanisms by which MCMV, and a growing number of other pathogens including reovirus, influenza, and vaccinia virus, thwart these defenses.
Areas:
- Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis.
- Murine Cytomegalovirus Deubiquitinase Regulates Viral Chemokine Levels To Control Inflammation and Pathogenesis
Research:
- Viral control of programmed cell death
- Beta Herpesvirus Deubiquitinases
- Beta Herpesvirus dUTPases
