The long-term goal of our research is to identify, characterize, and interrogate the molecular mechanisms important for virus-host interactions. Much of our work focuses on the pathogenesis of betaherpeviruses, which includes the human pathogen Human Cytomegalovirus (HCMV). HCMV is a significant cause of morbidity and mortality in immunocompromised individuals and is the leading infectious cause of congenital birth defects in the United States.
- Viral control of programmed cell death
- Beta Herpesvirus Deubiquitinases
- Beta Herpesvirus dUTPases
Subject area: Host-Microbial Interactions Core