134 Publications (Page 3 of 6)
2006
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt
Solenkova, Nataliya VSolodushko, ViktoriyaCohen, Michael and Downey, James M
American Journal of Physiology, vol. 59, (no. 1), pp. H441-H449, Jan 2006. | Journal Article
 
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
Solenkova, Nataliya VSolodushko, ViktoriyaCohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 290, (no. 1), pp. H441-9, 2006/Jan. | Journal Article
 
Localizing extracellular signal-regulated kinase (ERK) in pharmacological preconditioning's trigger pathway.
Philipp, SebastianCritz, Stuart DCui, LinSolodushko, ViktoriyaCohen, Michael V and Downey, James M
Basic research in cardiology, vol. 101, (no. 2), pp. 159-67, 2006/Mar. | Journal Article
 
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase.
Förster, KarinaPaul, InaSolenkova, NataliaStaudt, AlexanderCohen, Michael VDowney, James MFelix, Stephan B and Krieg, Thomas
Basic research in cardiology, vol. 101, (no. 4), pp. 319-26, 2006/Jul. | Journal Article
 
Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies.
Cohen, Michael VYang, Xi-Ming and Downey, James M
Cardiovascular research, vol. 70, (no. 2), pp. 231-9, 2006/May/1. | Journal Article
 
Protection from post-conditioning depends on the number of short ischemic insults in anesthetized pigs.
Iliodromitis, Efstathios KGeorgiadis, MichaelCohen, Michael VDowney, James MBofilis, Elias and Kremastinos, Dimitrios T
Basic research in cardiology, vol. 101, (no. 6), pp. 502-7, 2006/Nov. | Journal Article
2005
Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart.
Krieg, ThomasPhilipp, SebastianCui, LinDostmann, Wolfgang RDowney, James M and Cohen, Michael V
American journal of physiology. Heart and circulatory physiology, vol. 288, (no. 4), pp. H1976-81, 2005/Apr. | Journal Article
 
Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation.
Yang, Xi-MingPhilipp, SebastianDowney, James M and Cohen, Michael V
Basic research in cardiology, vol. 100, (no. 1), pp. 57-63, 2005/Jan. | Journal Article
2004
Acetylcholine and bradykinin trigger preconditioning in the heart through a pathway that includes Akt and NOS.
Krieg, ThomasQin, QiningPhilipp, SebastianAlexeyev, Mikhail FCohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 287, (no. 6), pp. H2606-11, 2004/Dec. | Journal Article
 
Efficacy of preconditioning should be gauged by reduction of infarction
Cohen, Michael
British Journal of Pharmacology, vol. 141, (no. 2), pp. 197-198, Jan 2004. | Journal Article
 
Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF.
Krieg, ThomasCui, LinQin, QiningCohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 36, (no. 3), pp. 435-43, 2004/Mar. | Journal Article
 
Protective and anti-protective effects of acute ethanol exposure in myocardial ischemia/reperfusion.
Krenz, MaikeCohen, Michael V and Downey, James M
Pathophysiology : the official journal of the International Society for Pathophysiology / ISP, vol. 10, (no. 2), pp. 113-9, 2004/Apr. | Journal Article
2003
Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase
Qin, QiningDowney, James M and Cohen, Michael
American Journal of Physiology, vol. 53, (no. 2), pp. H727-H734, Feb 2003. | Journal Article
 
Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase.
Qin, QiningDowney, James M and Cohen, Michael V
American journal of physiology. Heart and circulatory physiology, vol. 284, (no. 2), pp. H727-34, 2003/Feb. | Journal Article
 
Acetylcholine-induced production of reactive oxygen species in adult rabbit ventricular myocytes is dependent on phosphatidylinositol 3- and Src-kinase activation and mitochondrial K(ATP) channel opening.
Oldenburg, OlafCritz, Stuart DCohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 6), pp. 653-60, 2003/Jun. | Journal Article
 
Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals.
Krieg, ThomasLandsberger, MartinAlexeyev, Mikhail FFelix, Stephan BCohen, Michael V and Downey, James M
Cardiovascular research, vol. 58, (no. 1), pp. 196-202, 2003/Apr/1. | Journal Article
 
CGX-1051, a peptide from Conus snail venom, attenuates infarction in rabbit hearts when administered at reperfusion.
Zhang, Shi JYang, Xi-MingLiu, Guang SCohen, Michael VPemberton, Karen and Downey, James M
Journal of cardiovascular pharmacology, vol. 42, (no. 6), pp. 764-71, 2003/Dec. | Journal Article
 
Mitochondria and their role in preconditioning's trigger phase
Krieg, ThomasCohen, Michael and Downey, James M
Basic Research in Cardiology, vol. 98, (no. 4), pp. 228-234, Jul 2003. | Journal Article
 
Mitochondrial K(ATP) channels in preconditioning.
Oldenburg, OlafCohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 6), pp. 569-75, 2003/Jun. | Journal Article
 
P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.
Oldenburg, OlafYang, Xi-MingKrieg, ThomasGarlid, Keith DCohen, Michael VGrover, Gary J and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 9), pp. 1035-42, 2003/Sep. | Journal Article
2002
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Oldenburg, OlafQin, QiningSharma, Ana RCohen, Michael VDowney, James M and Benoit, Joseph N
Cardiovascular research, vol. 55, (no. 3), pp. 544-52, 2002/Aug/15. | Journal Article
 
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases
Krieg, ThomasQin, QiningMcIntosh, Elizabeth CCohen, Michael and Downey, James M
American Journal of Physiology, vol. 52, (no. 6), pp. H2322-H2330, Dec 2002. | Journal Article
 
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.
Krieg, ThomasQin, QiningMcIntosh, Elizabeth CCohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 283, (no. 6), pp. H2322-30, 2002/Dec. | Journal Article
 
Mitochondrial K(ATP) channels: role in cardioprotection.
Oldenburg, OlafCohen, Michael VYellon, Derek and Downey, James M
Cardiovascular research, vol. 55, (no. 3), pp. 429-37, 2002/Aug/15. | Journal Article
 
Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells.
Krenz, MaikeKrenz, MaikeOldenburg, OlafOldenburg, OlafWimpee, HollyWimpee, HollyCohen, Michael VCohen, Michael VGarlid, Keith DGarlid, Keith DCritz, Stuart DCritz, Stuart DDowney, James MDowney, James MBenoit, Joseph N and Benoit, Joseph N
Basic research in cardiology, vol. 97, (no. 5), pp. 365-73, 2002/Sep. | Journal Article