134 Publications (Page 3 of 6)
2006
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt
Solenkova, Nataliya V⋅Solodushko, Viktoriya⋅Cohen, Michael and Downey, James M
American Journal of Physiology, vol. 59, (no. 1), pp. H441-H449, Jan 2006. | Journal Article
 
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
Solenkova, Nataliya V⋅Solodushko, Viktoriya⋅Cohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 290, (no. 1), pp. H441-9, 2006/Jan. | Journal Article
 
Localizing extracellular signal-regulated kinase (ERK) in pharmacological preconditioning's trigger pathway.
Philipp, Sebastian⋅Critz, Stuart D⋅Cui, Lin⋅Solodushko, Viktoriya⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 101, (no. 2), pp. 159-67, 2006/Mar. | Journal Article
 
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase.
Förster, Karina⋅Paul, Ina⋅Solenkova, Natalia⋅Staudt, Alexander⋅Cohen, Michael V⋅Downey, James M⋅Felix, Stephan B and Krieg, Thomas
Basic research in cardiology, vol. 101, (no. 4), pp. 319-26, 2006/Jul. | Journal Article
 
Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies.
Cohen, Michael V⋅Yang, Xi-Ming and Downey, James M
Cardiovascular research, vol. 70, (no. 2), pp. 231-9, 2006/May/1. | Journal Article
 
Protection from post-conditioning depends on the number of short ischemic insults in anesthetized pigs.
Iliodromitis, Efstathios K⋅Georgiadis, Michael⋅Cohen, Michael V⋅Downey, James M⋅Bofilis, Elias and Kremastinos, Dimitrios T
Basic research in cardiology, vol. 101, (no. 6), pp. 502-7, 2006/Nov. | Journal Article
2005
Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart.
Krieg, Thomas⋅Philipp, Sebastian⋅Cui, Lin⋅Dostmann, Wolfgang R⋅Downey, James M and Cohen, Michael V
American journal of physiology. Heart and circulatory physiology, vol. 288, (no. 4), pp. H1976-81, 2005/Apr. | Journal Article
 
Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation.
Yang, Xi-Ming⋅Philipp, Sebastian⋅Downey, James M and Cohen, Michael V
Basic research in cardiology, vol. 100, (no. 1), pp. 57-63, 2005/Jan. | Journal Article
2004
Acetylcholine and bradykinin trigger preconditioning in the heart through a pathway that includes Akt and NOS.
Krieg, Thomas⋅Qin, Qining⋅Philipp, Sebastian⋅Alexeyev, Mikhail F⋅Cohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 287, (no. 6), pp. H2606-11, 2004/Dec. | Journal Article
 
Efficacy of preconditioning should be gauged by reduction of infarction
Cohen, Michael
British Journal of Pharmacology, vol. 141, (no. 2), pp. 197-198, Jan 2004. | Journal Article
 
Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF.
Krieg, Thomas⋅Cui, Lin⋅Qin, Qining⋅Cohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 36, (no. 3), pp. 435-43, 2004/Mar. | Journal Article
 
Protective and anti-protective effects of acute ethanol exposure in myocardial ischemia/reperfusion.
Krenz, Maike⋅Cohen, Michael V and Downey, James M
Pathophysiology : the official journal of the International Society for Pathophysiology / ISP, vol. 10, (no. 2), pp. 113-9, 2004/Apr. | Journal Article
2003
Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase
Qin, Qining⋅Downey, James M and Cohen, Michael
American Journal of Physiology, vol. 53, (no. 2), pp. H727-H734, Feb 2003. | Journal Article
 
Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase.
Qin, Qining⋅Downey, James M and Cohen, Michael V
American journal of physiology. Heart and circulatory physiology, vol. 284, (no. 2), pp. H727-34, 2003/Feb. | Journal Article
 
Acetylcholine-induced production of reactive oxygen species in adult rabbit ventricular myocytes is dependent on phosphatidylinositol 3- and Src-kinase activation and mitochondrial K(ATP) channel opening.
Oldenburg, Olaf⋅Critz, Stuart D⋅Cohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 6), pp. 653-60, 2003/Jun. | Journal Article
 
Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals.
Krieg, Thomas⋅Landsberger, Martin⋅Alexeyev, Mikhail F⋅Felix, Stephan B⋅Cohen, Michael V and Downey, James M
Cardiovascular research, vol. 58, (no. 1), pp. 196-202, 2003/Apr/1. | Journal Article
 
CGX-1051, a peptide from Conus snail venom, attenuates infarction in rabbit hearts when administered at reperfusion.
Zhang, Shi J⋅Yang, Xi-Ming⋅Liu, Guang S⋅Cohen, Michael V⋅Pemberton, Karen and Downey, James M
Journal of cardiovascular pharmacology, vol. 42, (no. 6), pp. 764-71, 2003/Dec. | Journal Article
 
Mitochondria and their role in preconditioning's trigger phase
Krieg, Thomas⋅Cohen, Michael and Downey, James M
Basic Research in Cardiology, vol. 98, (no. 4), pp. 228-234, Jul 2003. | Journal Article
 
Mitochondrial K(ATP) channels in preconditioning.
Oldenburg, Olaf⋅Cohen, Michael V and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 6), pp. 569-75, 2003/Jun. | Journal Article
 
P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.
Oldenburg, Olaf⋅Yang, Xi-Ming⋅Krieg, Thomas⋅Garlid, Keith D⋅Cohen, Michael V⋅Grover, Gary J and Downey, James M
Journal of molecular and cellular cardiology, vol. 35, (no. 9), pp. 1035-42, 2003/Sep. | Journal Article
2002
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Oldenburg, Olaf⋅Qin, Qining⋅Sharma, Ana R⋅Cohen, Michael V⋅Downey, James M and Benoit, Joseph N
Cardiovascular research, vol. 55, (no. 3), pp. 544-52, 2002/Aug/15. | Journal Article
 
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases
Krieg, Thomas⋅Qin, Qining⋅McIntosh, Elizabeth C⋅Cohen, Michael and Downey, James M
American Journal of Physiology, vol. 52, (no. 6), pp. H2322-H2330, Dec 2002. | Journal Article
 
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.
Krieg, Thomas⋅Qin, Qining⋅McIntosh, Elizabeth C⋅Cohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 283, (no. 6), pp. H2322-30, 2002/Dec. | Journal Article
 
Mitochondrial K(ATP) channels: role in cardioprotection.
Oldenburg, Olaf⋅Cohen, Michael V⋅Yellon, Derek and Downey, James M
Cardiovascular research, vol. 55, (no. 3), pp. 429-37, 2002/Aug/15. | Journal Article
 
Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells.
Krenz, Maike⋅Krenz, Maike⋅Oldenburg, Olaf⋅Oldenburg, Olaf⋅Wimpee, Holly⋅Wimpee, Holly⋅Cohen, Michael V⋅Cohen, Michael V⋅Garlid, Keith D⋅Garlid, Keith D⋅Critz, Stuart D⋅Critz, Stuart D⋅Downey, James M⋅Downey, James M⋅Benoit, Joseph N and Benoit, Joseph N
Basic research in cardiology, vol. 97, (no. 5), pp. 365-73, 2002/Sep. | Journal Article