17 Publications
2014
Vasoreparative Dysfunction of CD34+ Cells in Diabetic Individuals Involves Hypoxic Desensitization and Impaired Autocrine/Paracrine Mechanisms.
Jarajapu, Yagna PHazra, SugataSegal, MarkLicalzi, SergioJhadao, ChandraQian, KevinMitter, Sayak KRaizada, Mohan KBoulton, Mike E and Grant, Maria B
PloS one, vol. 9, (no. 4), pp. e93965, 2014. | Journal Article
2013
Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors.
Jarajapu, Yagna PBhatwadekar, Ashay DCaballero, SergioHazra, SugataShenoy, VinayakMedina, ReinholdKent, DavidStitt, Alan WThut, CatherineFinney, Eva MRaizada, Mohan K and Grant, Maria B
Diabetes, vol. 62, (no. 4), pp. 1258-69, 2013/Apr. | Journal Article
 
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
Shenoy, VinayakGjymishka, AltinJarajapu, Yagna PQi, YanfeiAfzal, AqeelaRigatto, KatyaFerreira, Anderson JFraga-Silva, Rodrigo AKearns, PatrickDouglas, Jane YAgarwal, DeepmalaMubarak, Kamal KBradford, ChastityKennedy, William RJun, Joo YRathinasabapathy, AnandharajanBruce, ErinGupta, DipankarCardounel, Arturo JMocco, JPatel, Jawaharlal MFrancis, JosephGrant, Maria BKatovich, Michael J and Raizada, Mohan K
American journal of respiratory and critical care medicine, vol. 187, (no. 6), pp. 648-57, 2013/Mar/15. | Journal Article
 
Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model.
Hazra, SJarajapu, Yagna PStepps, VCaballero, SThinschmidt, J SSautina, LBengtsson, NLicalzi, SDominguez, JKern, Timothy SSegal, Mark SAsh, J DSaban, DanielBartelmez, S H and Grant, Maria B
Diabetologia, vol. 56, (no. 3), pp. 644-53, 2013/Mar. | Journal Article
2012
Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.
Jarajapu, Yagna PCai, JunYan, YuanqingLi Calzi, SergioKielczewski, Jennifer LHu, PingShaw, LynnFirth, Sue MChan Ling, TailoiBoulton, Mike EBaxter, Robert C and Grant, Maria B
PloS one, vol. 7, (no. 7), pp. e39398, 2012. | Journal Article
2011
Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells.
Jarajapu, Yagna PCaballero, SergioVerma, AmrishaNakagawa, TakahikoLo, Margaret CLi, Qiuhong and Grant, Maria B
Investigative ophthalmology & visual science, vol. 52, (no. 8), pp. 5093-104, 2011/Jul. | Journal Article
 
Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide.
Mc Guane, JonathanDebrah, Julianna ESautina, LauraJarajapu, Yagna PNovak, JacquelineRubin, J. PGrant, Maria BSegal, Mark and Conrad, Kirk P
Endocrinology, vol. 152, (no. 7), pp. 2786-96, 2011/Jul. | Journal Article
 
Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species.
Kirabo, AnnetKearns, Patrick NJarajapu, Yagna PSasser, JenniferOh, Suk PGrant, Maria BKasahara, HidekoCardounel, Arturo JBaylis, ChrisWagner, Kay Uwe and Sayeski, Peter P
Cardiovascular research, vol. 91, (no. 1), pp. 171-9, 2011/Jul/1. | Journal Article
2010
Diabetic eNOS-knockout mice develop accelerated retinopathy.
Li, QiuhongVerma, AmrishaHan, Ping-YangNakagawa, TakahikoJohnson, Richard JGrant, Maria BCampbell Thompson, Martha LJarajapu, Yagna PLei, Bo and Hauswirth, William W
Investigative ophthalmology & visual science, vol. 51, (no. 10), pp. 5240-6, 2010/Oct. | Journal Article
 
The promise of cell-based therapies for diabetic complications: challenges and solutions.
Jarajapu, Yagna P and Grant, Maria B
Circulation research, vol. 106, (no. 5), pp. 854-69, 2010/Mar/19. | Journal Article
 
Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions.
Bhatwadekar, Ashay DGuerin, E PJarajapu, Yagna PCaballero, SergioSheridan, CarlKent, DavidKennedy, LaurenceLansang, M CRuscetti, Francis WPepine, Carl JHiggins, Paul JBartelmez, Stephen H and Grant, Maria B
Diabetes, vol. 59, (no. 8), pp. 2010-9, 2010/Aug. | Journal Article
2009
Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.
Kielczewski, Jennifer LJarajapu, Yagna PMcFarland, Evan LCai, JunAfzal, AqeelaLi Calzi, SergioChang, Kyung HLydic, ToddShaw, Lynn CBusik, JuliaHughes, JeffreyCardounel, Arturo JWilson, KennethLyons, Timothy JBoulton, Mike EMames, Robert NChan Ling, Tailoi and Grant, Maria B
Circulation research, vol. 105, (no. 9), pp. 897-905, 2009/Oct/23. | Journal Article
2008
Myogenic tone and reactivity of cerebral arteries in type II diabetic BBZDR/Wor rat.
Jarajapu, Yagna PGuberski, Dennis LGrant, Maria B and Knot, Harm J
European journal of pharmacology, vol. 579, (no. 1-3), pp. 298-307, 2008/Jan/28. | Journal Article
2007
Characteristics of myogenic tone in the rat ophthalmic artery
Ito, IsamuJarajapu, Yagna PGrant, Maria and Knot, Harm J
American Journal of Physiology, vol. 292, (no. 1), pp. H360, Jan 2007. | Journal Article
2006
Myogenic tone and reactivity of rat ophthalmic artery in acute exposure to high glucose and in a type II diabetic model.
Ito, IsamuJarajapu, Yagna PGuberski, Dennis LGrant, Maria B and Knot, Harm J
Investigative ophthalmology & visual science, vol. 47, (no. 2), pp. 683-92, 2006/Feb. | Journal Article
2005
Mechanisms of Decreased Myogenic Tone by Acute Exposure to High Glucose in the Rat Ophthalmic Artery
Ito, IsamuJarajapu, Yagna PGrant, Maria and Knot, Harm J
Diabetes, vol. 54, pp. A223, Jun 2005. | Journal Article
2004
Myogenic tone and reactivity of the rat ophthalmic artery.
Jarajapu, Yagna PGrant, Maria B and Knot, Harm J
Investigative ophthalmology & visual science, vol. 45, (no. 1), pp. 253-9, 2004/Jan. | Journal Article