36 Publications (Page 1 of 2)
2024
SimService: A Lightweight Library for Building Simulation Services in Python
2023
General, open-source vertex modeling in biological applications using Tissue Forge
Sego, T.J.⋅Comlekoglu, T.⋅Peirce, S.M.⋅Desimone, D.W. and Glazier, J.A.
Scientific Reports, vol. 13. | Journal Article
 
General, Open-Source Vertex Modeling in Biological Applications Using Tissue Forge
Sego, T.J.⋅Comlekoglu, T.⋅Peirce, S.M.⋅Desimone, D. and Glazier, J.A.
 
Mathematical Modeling of the Lethal Synergism of Coinfecting Pathogens in Respiratory Viral Infections: A Review
Mochan, E. and Sego, T.J.
Microorganisms, vol. 11. | Journal Article
 
Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm
 
PhenoCellPy: A Python package for biological cell behavior modeling
Gianlupi, J.F.⋅Sego, T.J.⋅Sluka, J.P. and Glazier, J.A.
 
Tissue Forge: Interactive biological and biophysics simulation environment. PLOS Computational Biology
. | Journal Article
2022
Age-Related Changes to the Immune System Exacerbate the Inflammatory Response to Pandemic H1N1 Infection
Mochan, E.⋅Sego, T.J. and Ermentrout, B.
Bulletin of Mathematical Biology, vol. 84. | Journal Article
 
A spatialised agent-based model of NOTCH signalling pathway in Endothelial Cells predicts emergent heterogeneity due to continual dynamic phenotypic adjustments.
 
Building digital twins of the human immune system: toward a roadmap
Niarakis, A.⋅Helikar, T.⋅An, G.⋅Shapiro, B.⋅Malik-Sheriff, R.S.⋅Sego, T.J.⋅Knapp, A.⋅Macklin, P. and Glazier, J.A.
npj Digital Medicine, vol. 5. | Journal Article
 
Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2.
Gianlupi, J.F.⋅Ferrari Gianlupi, Juliano⋅Mapder, Tarunendu⋅Sego, T J⋅Sluka, James P⋅Sluka, J.P.⋅Quinney, Sara K⋅Craig, Morgan⋅Stratford, Robert E and Glazier, James A
Viruses, vol. 14, (no. 3), March 14, 2022. | Journal Article
 
Tissue Forge: Interactive Biological and Biophysics Simulation Environment
2021
Advancing therapies for viral infections using mechanistic computational models of the dynamic interplay between the virus and host immune response
Zarnitsyna, V.I.⋅Gianlupi, J.F.⋅Hagar, A.⋅Sego, T.J. and Glazier, J.A.
Current Opinion in Virology, vol. 50, pp. 103-109. | Journal Article
 
A Multiscale Multicellular Spatiotemporal Model of Local Influenza Infection and Immune Response
 
A Multiscale Multicellular Spatiotemporal Model of Local Influenza Infection and Immune Response
Journal of Theoretical Biology. | Journal Article
 
Compartmental Model Suggests Importance of Innate Immune Response to COVID-19 Infection in Rhesus Macaques
Mochan, E.⋅Sego, T.J.⋅Gaona, L.⋅Rial, E. and Ermentrout, G.B.
Bulletin of Mathematical Biology, vol. 83. | Journal Article
 
Generating Agent-Based Multiscale Multicellular Spatiotemporal Models from Ordinary Differential Equations of Biological Systems, with Applications in Viral Infection
 
Generation of multicellular spatiotemporal models of population dynamics from ordinary differential equations, with applications in viral infection
BMC Biology. | Journal Article
 
Multicellular spatial model of RNA virus replication and interferon responses reveals factors controlling plaque growth dynamics
Aponte-Serrano, Josua O.⋅Weaver, Jordan J. A.⋅Sego, T. J.⋅Glazier, James A. and Shoemaker, Jason E.
PLOS Computational Biology. | Journal Article
 
Multicellular Spatial Model of RNA Virus Replication and Interferon Responses Reveals Factors Controlling Plaque Growth Dynamics
2020
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
Sego, T. J.⋅Aponte-Serrano, Josua O.⋅Gianlupi, Juliano Ferrari⋅Heaps, Samuel R.⋅Breithaupt, Kira⋅Brusch, Lutz⋅Crawshaw, Jessica⋅Osborne, James M.⋅Quardokus, Ellen M.⋅Plemper, Richard K. and Glazier, James A.
PLOS Computational Biology. | Journal Article
 
A modular framework for multiscale spatial modeling of viral infection and immune response in epithelial tissue
Sego, T.J.⋅Aponte-Serrano, J.O.⋅Gianlupi, J.F.⋅Heaps, S.R.⋅Breithaupt, K.⋅Brusch, L.⋅Osborne, J.M.⋅Quardokus, E.M.⋅Plemper, R.K. and Glazier, J.A.
 
Cover Image
Sego, T. J⋅Sego, T. J.⋅Sego, T. J.⋅Sego, T. J.⋅Sego, T. J⋅Prideaux, Matthew⋅Prideaux, Matthew⋅Prideaux, Matthew⋅Prideaux, Matthew⋅Prideaux, Matthew⋅Sterner, Jane⋅Sterner, Jane⋅Sterner, Jane⋅Sterner, Jane⋅Sterner, Jane⋅McCarthy, Brian Paul⋅McCarthy, Brian Paul⋅McCarthy, Brian Paul⋅McCarthy, Brian Paul⋅McCarthy, Brian Paul⋅Li, Ping⋅Li, Ping⋅Li, Ping⋅Li, Ping⋅Li, Ping⋅Bonewald, Lynda F.⋅Bonewald, Lynda F.⋅Bonewald, Lynda F.⋅Bonewald, Lynda F⋅Bonewald, Lynda F⋅Ekser, Burcin⋅Ekser, Burcin⋅Ekser, Burcin⋅Ekser, Burcin⋅Ekser, Burcin⋅Tovar, Andres⋅Tovar, Andres⋅Tovar, Andres⋅Tovar, Andres⋅Tovar, Andres⋅Jeshua Smith, Lester⋅Smith, Lester Jeshua⋅Smith, Lester Jeshua⋅Jeshua Smith, Lester and Jeshua Smith, Lester
Biotechnology and Bioengineering, vol. 117. | Journal Article
 
Modeling Progressive Damage Accumulation in Bone Remodeling Explains the Thermodynamic Basis of Bone Resorption by Overloading
Sego, T J⋅Hsu, Yung-Ting⋅Chu, Tien-Min and Tovar, Andres
Bulletin of Mathematical Biology. | Journal Article
 
Unification of aggregate growth models by emergence from cellular and intracellular mechanisms
Sego, T J⋅Glazier, James A and Tovar, Andres
Royal Society Open Science. | Journal Article