Expertise

Research Interests:

  • Biological silica - Novel methods for cell encapsulation and transplantation
  • Biosensors for measurement of neurotransmitter release and reuptake in single cells
  • Biomaterial approaches to the brain - tissue interface
  • Biomaterial approaches to directing cell fate in neural and cancer stem cells
  • Disease emphasis on applications in epilepsy, diabetes, and cancer

Current Research Areas & Applications

  • Material Systems of Interest
    • Glioblastoma - Grade IV Brain Tumors:Tissue Engineered 3D Brain Mimics for Glioblastoma Research and Therapy Development
    • High Density Array Biosensors for Spatial Mapping of Cellular Gradients and Flux
    • Multi-Optrode Arrays (MOAs) for Quantification of Biological Gradients

Areas of Interest

  • Biological Engineering

Keywords: Biofunctional Materials for Cell Sensing and Actuation


Subject areas:

  • Biomaterials.
  •  Materials to measure, control, and mimic living cells.
  • Biosensors.
  • Nano/micro biosensors for cell physiology. 
  • Applications in cell transplantation, bioreactors, implantable devices.

Expertise: Computational Biomedicine

Affiliations

Professor, Weldon School of Biomedical Engineering, College of Engineering, Purdue University

Center for the Cure of Glioblastoma, Centers and Institutes, Indiana University School of Medicine

Past Affiliations

Bindley Bioscience Center, Discovery Park District, Office of Research, Purdue University (past)

Professor, Purdue Center for Cancer Research, Office of Research, Purdue University (past)

Professor, Department of Agricultural and Biological Engineering, College of Engineering, Purdue University (past)

Professor, Integrative Neuroscience, Graduate School, Purdue University (past)

Associate Professor, Department of Agricultural and Biological Engineering, College of Engineering, Purdue University (past)

Assistant Professor, Department of Agricultural and Biological Engineering, College of Engineering, Purdue University (past)

Associate Professor, Weldon School of Biomedical Engineering, College of Engineering, Purdue University (past)

Assistant Professor, Weldon School of Biomedical Engineering, College of Engineering, Purdue University (past)

Assistant Professor, School of Engineering Education, College of Engineering, Purdue University (past)

Communities
Biotechnology, Agricultural Engineering, Oncology, Biomedical Engineering, Neuroscience, Environmental Engineering
Degrees
PhD, University of California, Los Angeles, NeuroEngineering, 2003
BS, Purdue University, Agricultural and Biological Engineering, 1995
BS, Purdue University, Biochemistry, 1995
Keywords
biosensors agricultural engineering biological engineering bioengineering biological markers & sensor mechanisms