Biomedical vision, computational biology, computer vision, and pattern recognition are the domains of Dr. Tsechpenakis' research. He works with image segmentation with deformable models and learning-based classification approaches, object recognition, feature tracking, 3D shape estimation and tracking of articulated and deformable structures, 3D shape recovery from 2D data, high throughput spatio-temporal analysis, content-based image retrieval, human motion analysis, temporal change-point detection, and semantic knowledge extraction.