154 Publications (Page 3 of 7)
2019
Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets
Sato, Keisaku⋅Sato, Keisaku⋅Glaser, Shannon⋅Glaser, Shannon⋅Kennedy, Lindsey⋅Kennedy, Lindsey⋅Liangpunsakul, Suthat⋅Liangpunsakul, Suthat⋅Meng, Fanyin⋅Meng, Fanyin⋅Francis, Heather⋅Francis, Heather⋅Alpini, Gianfranco and Alpini, Gianfranco
Expert Opinion on Therapeutic Targets, vol. 23, (no. 6), pp. 472, 6/3/2019. | Journal Article
 
Sa1502 – Knockout (KO) of the Melatonin Receptor, Mt2, Enhances Alcohol-Induced Ductular Reaction (DR), Biliary Senescence and Hepatic Fibrosis During Alcoholic Liver Disease (ALD)
Wu, Nan⋅Wu, Nan⋅Guillot, Adrien⋅Guillot, Adrien⋅Zhou, Tianhao⋅Zhou, Tianhao⋅Venter, Julie⋅Venter, Julie⋅Kennedy, Lindsey⋅Kennedy, Lindsey⋅Kyritsi, Konstantina⋅Kyritsi, Konstantina⋅Ceci, Ludovica⋅Ceci, Ludovica⋅Chen, Lixian⋅Chen, Lixian⋅Francis, Heather L⋅Francis, Heather L⋅White, Tori⋅White, Tori⋅Gao, Bin⋅Gao, Bin⋅Liangpunsakul, Suthat⋅Liangpunsakul, Suthat⋅Zawieja, David C⋅Zawieja, David C⋅Alpini, Gianfranco⋅Alpini, Gianfranco⋅Glaser, Shannon⋅Glaser, Shannon⋅Meng, Fanyin and Meng, Fanyin
Gastroenterology, vol. 156, (no. 6), pp. S-1226, May 2019. | Journal Article
 
Sa1508 – Biliary L-Histidine Decarboxylase (HDC) Activity Induces Ductular Reaction (DR) and Subsequent Liver Fibrosis During Alcoholic Liver Injury (ALI)
Kennedy, Lindsey⋅Kennedy, Lindsey⋅Demieville, Jennifer⋅Demieville, Jennifer⋅Hargrove, Laura⋅Hargrove, Laura⋅Meadows, Vik⋅Meadows, Vik⋅Meng, Fanyin⋅Meng, Fanyin⋅Glaser, Shannon⋅Glaser, Shannon⋅Tolefree, Julie Ann⋅Tolefree, Julie Ann⋅Reinhart, Evan⋅Reinhart, Evan⋅Virani, Shohaib⋅Virani, Shohaib⋅Liangpunsakul, Suthat⋅Liangpunsakul, Suthat⋅Alpini, Gianfranco⋅Alpini, Gianfranco⋅Francis, Heather L and Francis, Heather L
Gastroenterology, vol. 156, (no. 6), pp. S-1228, May 2019. | Journal Article
 
Sa1510 – Increased Serotonin (5HT) Biliary Synthesis Due to Enhanced Expression of Tryptophan Hydroxylase1 (TPH1) and Reduced Monoamine-Oxidase-A (MAO-A) Expression is Couple with Alcohol-Induced Liver Injury (ALI)
Kyritsi, Konstantina⋅Kyritsi, Konstantina⋅Chen, Lixian⋅Chen, Lixian⋅Venter, Julie⋅Venter, Julie⋅Zhou, Tianhao⋅Zhou, Tianhao⋅Ceci, Ludovica⋅Ceci, Ludovica⋅Kennedy, Lindsey⋅Kennedy, Lindsey⋅Guillot, Adrien⋅Guillot, Adrien⋅Francis, Heather L⋅Francis, Heather L⋅Gao, Bin⋅Gao, Bin⋅Wu, Nan⋅Wu, Nan⋅White, Tori⋅White, Tori⋅Liangpunsakul, Suthat⋅Liangpunsakul, Suthat⋅Meng, Fanyin⋅Meng, Fanyin⋅Alpini, Gianfranco⋅Alpini, Gianfranco⋅Glas, Shannon and Glas, Shannon
Gastroenterology, vol. 156, (no. 6), pp. S-1229, May 2019. | Journal Article
 
Sa1520 – Knockdown of Stimulator of Interferon Genes (STING) Reduces Biliary Senescence and Liver Inflammation and Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis (PSC)
Zhou, Tianhao⋅Chen, Lixian⋅Wu, Nan⋅Kyritsi, Konstantina⋅Venter, Julie⋅Ceci, Ludovica⋅Meng, Fanyin⋅Kennedy, Lindsey⋅Francis, Heather L⋅Zawieja, David C⋅Gashev, Anatoliy⋅Alpini, Gianfranco⋅Wu, Chaodong and Glaser, Shannon
Gastroenterology, vol. 156, (no. 6), pp. S-1231, May 2019. | Journal Article
 
Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early‐stage primary biliary cholangitis
Kennedy, Lindsey⋅Francis, Heather⋅Invernizzi, Pietro⋅Venter, Julie⋅Wu, Nan⋅Carbone, Marco⋅Eric Gershwin, M⋅Bernuzzi, Francesca⋅Franchitto, Antonio⋅Alvaro, Domenico⋅Marzioni, Marco⋅Onori, Paolo⋅Gaudio, Eugenio⋅Sybenga, Amelia⋅Fabris, Luca⋅Meng, Fanyin⋅Glaser, Shannon and Alpini, Gianfranco
The FASEB Journal, vol. 33, (no. 9), pp. 10279, September 2019. | Journal Article
 
Su1023 – Regulation of Endothelial Progenitor Cell Function by Microrna in Cholestatic Liver Injury
Zhou, Tianhao⋅Wu, Nan⋅McDaniel, Kelly M⋅Glaser, Shannon⋅Francis, Heather L⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 156, (no. 6), pp. S-1267, May 2019. | Journal Article
 
Su1545 – Differential Dna Methylation Status in Core Clock Genes Leads to Altered Circadian Rhythm in High-Fat Diet Fed Mice
Han, Yuyan⋅Cheplick, Faith⋅Wu, Nan⋅Zhou, Tianhao⋅Kennedy, Lindsey⋅Francis, Heather L⋅Meng, Fanyin⋅Chen, Lixian⋅Glaser, Shannon and Alpini, Gianfranco
Gastroenterology, vol. 156, (no. 6), pp. S-1294, May 2019. | Journal Article
2018
245 - Liver Specific Deletion of Microrna-34A Alleviates Cellular Senescence and Liver Fibrosis During Experimental Cholestasis
Zhou, Tianhao⋅McDaniel, Kelly M⋅Ramos-Lorenzo, Sugeily⋅Wu, Nan⋅Francis, Heather L⋅Glaser, Shannon⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 154, (no. 6), pp. S-1079, May 2018. | Journal Article
 
507 - Mast Cells Promote Biliary Damage and Angiogenesis via Increased TGF-β1 Signaling in Normal and Mast Celldeficient Mice
Hargrove, Laura⋅Kennedy, Lindsey⋅Demieville, Jennifer⋅Meadows, Victoria⋅Stephenson, Kristen⋅Smith, Steven⋅Virani, Shohaib and Francis, Heather L
Gastroenterology, vol. 154, (no. 6), pp. S-1094, May 2018. | Journal Article
 
509 - Therapeutic Effects of Extracellular Vesicles Isolated from Cholangiocytes Lacking the Secretin/Secretin Receptor (SCT/SRT) Axis on a Mouse Model of Primary Sclerosing Cholangitis
Keisaku, Sato⋅Venter, Julie⋅Giang, Thao⋅Francis, Heather L⋅Glaser, Shannon⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 154, (no. 6), pp. S-1095, May 2018. | Journal Article
 
513 - Senescent Cholangiocytes Induce Mast Cell Migration, which Exacerbates Hepatic Damage and Fibrosis Following High Fat Diet Feeding
Kennedy, Lindsey⋅Demieville, Jennifer⋅Hargrove, Laura⋅Meadows, Victoria⋅Polireddy, Kishore⋅Bailey, Jennifer M⋅Dar, Wasim and Francis, Heather L
Gastroenterology, vol. 154, (no. 6), pp. S-1096, May 2018. | Journal Article
 
557 - Melatonin and Dark Therapy Reduce Biliary Damage, Liver Fibrosis and Angiogenesis in a Murine Model of Early Stage Primary Biliary Cholangitis (PBC)
Kennedy, Lindsey⋅Wu, Nan⋅Francis, Heather L⋅Venter, Julie⋅Meng, Fanyin⋅Mancinelli, Romina⋅Bennett, Morgan⋅Giang, Thao⋅Invernizzi, Pietro⋅Bernuzzi, Francesca⋅Onori, Paolo⋅Franchitto, Antonio⋅Kyritsi, Konstantina⋅Zhou, Tianhao⋅Alvaro, Domenico⋅Gaudio, Eugenio⋅Glaser, Shannon and Alpini, Gianfranco
Gastroenterology, vol. 154, (no. 6), pp. S-1097, May 2018. | Journal Article
 
Comprehensive Review of Molecular Mechanisms during Cholestatic Liver Injury and Cholangiocarcinoma.
Virani, Shohaib⋅Akers, Austin⋅Stephenson, Kristen⋅Smith, Steven⋅Kennedy, Lindsey⋅Alpini, Gianfranco and Francis, Heather
Journal of liver, vol. 7, (no. 3), 2018. | Journal Article
 
Mo1372 - Loss of the Biliary Secretin/Secretin Receptor (SCT/SR) Axis Decreases Liver Fibrosis by Enhanced Senescence of Hepatic Stellate Cells (HSCS) Through Decreased Biliary Secretion of TGFβ1
Wu, Nan⋅Zhou, Tianhao⋅Venter, Julie⋅Wu, Chaodong⋅Onori, Paolo⋅Alvaro, Domenico⋅Franchitto, Antonio⋅Meng, Fanyin⋅Giang, Thao⋅Gaudio, Eugenio⋅Francis, Heather L⋅Kyritsi, Konstantina⋅Alpini, Gianfranco and Glaser, Shannon
Gastroenterology, vol. 154, (no. 6), pp. S-1185, May 2018. | Journal Article
 
Mo1373 - Knockout of Secretin/Secretin Receptor Axis (SCT/SR) Reduces Liver Fibrosis by Angiogenesis-Dependent Reduced Senescence of Cholangiocytes but Increased Senescence of Hepatic Stellate Cells (HSCS) in the MDR2−/− Mouse Model of Primary Sclerosing Cholangitis (PSC)
Zhou, Tianhao⋅Kyritsi, Konstantina⋅Wu, Nan⋅Venter, Julie⋅Francis, Heather L⋅Meng, Fanyin⋅Chen, Lixian⋅Giang, Thao⋅White, Tori⋅Alpini, Gianfranco and Glaser, Shannon
Gastroenterology, vol. 154, (no. 6), pp. S-1185, May 2018. | Journal Article
 
Mo1376 - Therapeutic Effects of Microrna-21 Depletion on Inflammatory Response in Liver Macrophages During Cholestatic Liver Injury
Sato, Keisaku⋅Kennedy, Lindsey⋅Giang, Thao⋅Zhou, Tianhao⋅Ramos-Lorenzo, Sugeily⋅Francis, Heather L⋅Glaser, Shannon⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 154, (no. 6), pp. S-1187, May 2018. | Journal Article
 
Sa1453 - Secretin Knockout Reduces Liver Damage in Alcoholic Liver Disease
McDaniel, Kelly⋅Guillot, Adrien⋅Wu, Nan⋅Kyritsi, Konstantina⋅Ramos-Lorenzo, Sugeily⋅Giang, Thao⋅Francis, Heather L⋅Venter, Julie⋅Glaser, Shannon⋅Meng, Fanyin⋅Gao, Bin and Alpini, Gianfranco
Gastroenterology, vol. 154, (no. 6), pp. S-1118, May 2018. | Journal Article
 
Sa1466 - Knockout of Microrna-21 Attenuates Alcoholic Hepatitis Through VHL/NF-KB Signaling Pathway
Wu, Nan⋅Sato, Keisaku⋅Kennedy, Lindsey⋅Zhou, Tianhao⋅McDaniel, Kelly M⋅Ramos-Lorenzo, Sugeily⋅Francis, Heather L⋅Glaser, Shannon⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 154, (no. 6), pp. S-1122, May 2018. | Journal Article
 
Updates on Dietary Models of Nonalcoholic Fatty Liver Disease: Current Studies and Insights
Stephenson, Kristen⋅Kennedy, Lindsey⋅Hargrove, Laura⋅Demieville, Jennifer⋅Thomson, Joanne⋅Alpini, Gianfranco and Francis, Heather
Gene Expression, vol. 18, (no. 1), pp. 5-17, 2018. | Journal Article
2017
Bile duct ligation–induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell–deficient KitW‐sh mice
Hargrove, Laura⋅Kennedy, Lindsey⋅Demieville, Jennifer⋅Jones, Hannah⋅Meng, Fanyin⋅DeMorrow, Sharon⋅Karstens, Walker⋅Madeka, Taronish⋅Greene, John and Francis, Heather
Hepatology, vol. 65, (no. 6), pp. 2004, June 2017. | Journal Article
 
Characterization of Endothelial Dysfunction in Microrna-34A Knockout Mice with Alcoholic Liver Injury
Wan, Ying⋅McDaniel, Kelly⋅Wu, Nan⋅Ramos-Lorenzo, Sugeily⋅Zhou, Tianhao⋅Sato, Keisaku⋅Venter, Julie⋅Francis, Heather⋅Glaser, Shannon⋅Tsukamoto, Hidekazu⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 152, (no. 5), pp. S1111, 2017. | Journal Article
 
Commonly Used H1 and H2 Histamine Receptor (HR) Blockers Decrease Cholangiocarcinoma Xenograft Tumor Growth, Angiogenesis and EMT
Hargrove, Laura⋅Kennedy, Lindsey⋅Demieville, Jennifer⋅Karstens, Allen⋅Smith, Steven and Francis, Heather
Gastroenterology, vol. 152, (no. 5), pp. S1183, 2017. | Journal Article
 
Depletion of Microrna-21 Reduces Infiltration of Macrophages and Neutrophils in the Liver and Attenuates Inflammatory Cytokine Production in Liver Macrophages During Experimental Cholestatic Liver Injury
Sato, Keisaku⋅Kennedy, Lindsey⋅Zhou, Tianhao⋅McDaniel, Kelly⋅Ramos-Lorenzo, Sugeily⋅Wan, Ying⋅Venter, Julie⋅Francis, Heather⋅Glaser, Shannon⋅Alpini, Gianfranco and Meng, Fanyin
Gastroenterology, vol. 152, (no. 5), pp. S1064, 2017. | Journal Article
 
High Fat Diet-Induced Biliary Damage, Steatosis, Inflammation and Hepatic Fibrosis are Decreased in Mast Cell-Deficient Mice
Kennedy, Lindsey⋅Demieville, Jennifer⋅Hargrove, Laura and Francis, Heather
Gastroenterology, vol. 152, (no. 5), pp. S1067, 2017. | Journal Article