51 Publications (Page 1 of 3)
2021
Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells
Strittmatter, Brady G⋅Strittmatter, Brady G⋅Jerde, Travis J⋅Jerde, Travis J⋅Hollenhorst, Peter C and Hollenhorst, Peter C
PLoS Genetics, vol. 17, (no. 7), Jul 2021. | Journal Article
2020
­­A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS
Nicholas, Taylor R⋅Meng, Jingwei⋅Greulich, Benjamin M⋅Morris, Teresa S and Hollenhorst, Peter C
PLoS One, vol. 15, (no. 9), Sep 2020. | Journal Article
2019
Oncogenic ETS Factors in Prostate Cancer
Nicholas, Taylor R⋅Strittmatter, Brady G and Hollenhorst, Peter C
Advances in experimental medicine and biology, vol. 1210, pp. 409, 2019-00-00. | Journal Article
2018
Abstract A023: Regulation of ERG function in prostate cells by phosphorylation and interaction with Ewing’s sarcoma breakpoint protein EWS
Kedage, Vivekananda⋅Kedage, Vivekananda⋅Nicholas, Taylor R⋅Nicholas, Taylor R⋅Strittmatter, Brady G⋅Strittmatter, Brady G⋅Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Budka, Justin A⋅Budka, Justin A⋅Jerde, Travis J⋅Jerde, Travis J⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Cancer Research, vol. 78, (no. 16 Supplement), pp. A023, 2018-08-15. | Journal Article
 
Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance
Budka, Justin A⋅Ferris, Mary W⋅Capone, Matthew J and Hollenhorst, Peter C
Genes & cancer, vol. 9, (no. 5-6), pp. 214, 2018-May. | Journal Article
 
Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites
Madison, Bethany J⋅Madison, Bethany J⋅Clark, Kathleen A⋅Clark, Kathleen A⋅Bhachech, Niraja⋅Bhachech, Niraja⋅Hollenhorst, Peter⋅Hollenhorst, Peter C⋅Graves, Barbara J⋅Graves, Barbara J⋅Currie, Simon L and Currie, Simon L
The Journal of biological chemistry, vol. 293, (no. 48), pp. 18635, 2018-11-30. | Journal Article
 
ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase
Tomar, Sunil⋅Tomar, Sunil⋅Plotnik, Joshua P⋅Plotnik, Joshua P⋅Haley, James⋅Haley, James⋅Scantland, Joshua⋅Scantland, Joshua⋅Dasari, Subramanyam⋅Dasari, Subramanyam⋅Sheikh, Zahir⋅Sheikh, Zahir⋅Emerson, Robert⋅Emerson, Robert⋅Lenz, Dean⋅Lenz, Dean⋅Hollenhorst, Peter C⋅Hollenhorst, Peter C⋅Mitra, Anirban K and Mitra, Anirban K
Cancer Letters, vol. 414, pp. 204, 2018-02-01. | Journal Article
 
Therapeutic Targeting of TFE3/IRS-1/PI3K/mTOR Axis in Translocation Renal Cell Carcinoma
Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Budka, Justin A⋅Budka, Justin A⋅Budka, Justin A⋅Budka, Justin A⋅Khella, Heba W Z⋅Khella, Heba W⋅Khella, Heba W Z⋅Khella, Heba W Z⋅Ferris, Mary W⋅Ferris, Mary W⋅Ferris, Mary W⋅Ferris, Mary W⋅Ku, Sheng Y⋅Ku, Sheng Yu⋅Ku, Sheng Yu⋅Ku, Sheng Yu⋅Kauffman, Eric⋅Kauffman, Eric⋅Kauffman, Eric⋅Kauffman, Eric⋅Wood, Anthony C⋅Wood, Anthony C⋅Wood, Anthony C⋅Wood, Anthony C⋅Ahmed, Khunsha⋅Ahmed, Khunsha⋅Ahmed, Khunsha⋅Ahmed, Khunsha⋅Chintala, Venkata Nithinsai⋅Chintala, Venkata Nithinsai⋅Chintala, Venkata Nithinsai⋅Chintala, Venkata N⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Kao, Chinghai⋅Kao, Chinghai⋅Kao, Chinghai⋅Kao, Chinghai⋅Linehan, W Marston⋅Linehan, W Marston⋅Linehan, W M⋅Linehan, W Marston⋅Yousef, George M⋅Yousef, George M⋅Yousef, George M⋅Yousef, George M⋅Hollenhorst, Peter C⋅Hollenhorst, Peter C⋅Hollenhorst, Peter C⋅Hollenhorst, Peter C⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto and Pili, Roberto
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 24, (no. 23), pp. 5989, 2018-Dec-01. | Journal Article
2017
Abstract 3510: A role for the Ewing’s sarcoma breakpoint protein EWS in ERG-induced prostate tumorigenesis
Kedage, Vivekananda⋅Kedage, Vivekananda⋅Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Nicholas, Taylor R⋅Nicholas, Taylor R⋅Budka, Justin A⋅Budka, Justin A⋅Jerde, Travis J⋅Jerde, Travis J⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Cancer Research, vol. 77, (no. 13 Supplement), pp. 3510, 2017-07-01. | Journal Article
 
EZH2 Modifies Sunitinib Resistance in Renal Cell Carcinoma by Kinome Reprogramming
Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Adelaiye-Ogala, Remi⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Budka, Justin⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Damayanti, Nur P⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Arrington, Justine⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Ferris, Mary⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Hsu, Chuan-Chih⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Chintala, Sreenivasulu⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Orillion, Ashley⋅Miles, Kiersten Marie⋅Miles, Kiersten Marie⋅Miles, Kiersten Marie⋅Miles, Kiersten Marie⋅Miles, Kiersten M⋅Miles, Kiersten Marie⋅Miles, Kiersten M⋅Miles, Kiersten Marie⋅Miles, Kiersten Marie⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Shen, Li⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Elbanna, May⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Ciamporcero, Eric⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Arisa, Sreevani⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Pettazzoni, Piergiorgio⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Draetta, Giulio F⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Seshadri, Mukund⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Hancock, Bradley⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Radovich, Milan⋅Kota, Janaiah⋅Kota, Janaiah⋅Kota, Janaiah⋅Kota, Janaiah⋅Kota, Janaiah⋅Kota, Janaiah⋅Kota, Janaiah⋅Janaiah, Kota⋅Kota, Janaiah⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Buck, Michael⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅Keilhack, Heike⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅McCarthy, Brian P⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Persohn, Scott A⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Zang, Yong⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Irudayaraj, Joseph⋅Tao, W Andy⋅Tao, W Andy⋅Tao, W Andy⋅Tao, W Andy⋅Tao, W Andy⋅Andy, Tao W⋅Tao, W Andy⋅Tao, W A⋅Tao, W Andy⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Hollenhorst, Peter⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto⋅Pili, Roberto and Pili, Roberto
Cancer research, vol. 77, (no. 23), pp. 6666, 2017-12-01. | Journal Article
 
Genome-Wide Analysis of RAS/ERK Signaling Targets
Plotnik, Joshua P⋅Plotnik, Joshua P⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Methods in molecular biology (Clifton, N.J.), vol. 1487, pp. 288, 2017-00-00. | Journal Article
 
Genome-Wide Analysis of RAS/ERK Signaling Targets.
Plotnik, Joshua P⋅Plotnik, Joshua P⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Methods in molecular biology (Clifton, N.J.), vol. 1487, pp. 277-288, 2017. | Journal Article
 
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.
Plotnik, Joshua P and Hollenhorst, Peter C
Nucleic acids research, January 23, 2017. | Journal Article
 
Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation
Kedage, Vivekananda⋅Strittmatter, Brady G⋅Dausinas, Paige B and Hollenhorst, Peter C
The Journal of biological chemistry, vol. 292, (no. 42), pp. 17235, 2017-10-20. | Journal Article
 
Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma
Potu, Harish⋅H, Potu⋅LF, Peterson⋅Peterson, Luke⋅M, Kandarpa⋅Kandarpa, Malathi⋅Pal, Anupama⋅A, Pal⋅Sun, Hanshi⋅Durham, Alison⋅Harms, Paul⋅PW, Harms⋅PC, Hollenhorst⋅Hollenhorst, Peter⋅U, Eskiocak⋅Eskiocak, Ugur⋅Talpaz, Moshe⋅NJ, Donato and Donato, Nicholas
Nature Communications, vol. 8, pp. 14449, Feb 2017. | Journal Article
2016
Abstract 2881: Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma
Potu, Harish⋅Peterson, Luke F. Peterson⋅Kandarpa, Malathi Kandarpa⋅Pal, Anupama Pal⋅Sun, Hanshi Sun⋅Harms, Paul W. Harms⋅Hollenhorst, Peter C. Hollenhorst⋅Eskiocak, Ugur Eskiocak⋅Talpaz, Moshe Talpaz and Donato, Nicholas J. Donato
Cancer Research, vol. 76, (no. 14 Supplement), pp. 2881, 2016-07-15. | Journal Article
 
An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.
Kedage, Vivekananda⋅Kedage, Vivekananda⋅Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Nicholas, Taylor R⋅Nicholas, Taylor R⋅Budka, Justin A⋅Budka, Justin A⋅Plotnik, Joshua P⋅Plotnik, Joshua P⋅Jerde, Travis J⋅Jerde, Travis J⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Cell reports, vol. 17, (no. 5), pp. 1289-1301, October 25, 2016. | Journal Article
2015
Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells
Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Kedage, Vivekananda⋅Kedage, Vivekananda⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Cell communication and signaling : CCS, vol. 13, (no. 1), pp. 12, 2015-Feb-19. | Journal Article
 
Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells.
Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Kedage, Vivekananda⋅Kedage, Vivekananda⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Cell communication and signaling : CCS, vol. 13, pp. 12, 2015. | Journal Article
 
Extracellular signal-regulated kinase signaling regulates the opposing roles of JUN family transcription factors at ETS/AP-1 sites and in cell migration.
Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Budka, Justin A⋅Budka, Justin A⋅Ferris, Mary W⋅Ferris, Mary W⋅Plotnik, Joshua P⋅Plotnik, Joshua P⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Molecular and cellular biology, vol. 35, (no. 1), pp. 88-100, January 2015. | Journal Article
 
Extracellular Signal-Regulated Kinase Signaling Regulates the Opposing Roles of JUN Family Transcription Factors at ETS/AP-1 Sites and in Cell Migration
Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Budka, Justin A⋅Budka, Justin A⋅Ferris, Mary W⋅Ferris, Mary W⋅Plotnik, Joshua P⋅Plotnik, Joshua P⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Molecular and cellular biology, vol. 35, (no. 1), pp. 100, 2015-Jan. | Journal Article
2014
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells
Plotnik, Joshua P⋅Plotnik, Joshua P⋅Budka, Justin A⋅Budka, Justin A⋅Ferris, Mary W⋅Ferris, Mary W⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Nucleic acids research, vol. 42, (no. 19), pp. 11940, 2014-Oct-29. | Journal Article
 
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells.
Plotnik, Joshua P⋅Plotnik, Joshua P⋅Budka, Justin A⋅Budka, Justin A⋅Ferris, Mary W⋅Ferris, Mary W⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Nucleic acids research, vol. 42, (no. 19), pp. 11928-11940, October 29, 2014. | Journal Article
 
Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation.
Selvaraj, Nagarathinam⋅Selvaraj, Nagarathinam⋅Budka, Justin A⋅Budka, Justin A⋅Ferris, Mary W⋅Ferris, Mary W⋅Jerde, Travis J⋅Jerde, Travis J⋅Hollenhorst, Peter C and Hollenhorst, Peter C
Molecular cancer, vol. 13, pp. 61, 2014. | Journal Article
2012
Abstract 3090: Oncogenic ETS transcription factors bind ETS/AP-1 sequences and activate a RAS/MAPK gene expression program in the absence of MAPK activation
Hollenhorst, Peter C⋅Hollenhorst, Peter C⋅Ferris, Mary W⋅Ferris, Mary W⋅Hull, Megan A⋅Hull, Megan A⋅Chae, Heejoon⋅Chae, Heejoon⋅Kim, Sun⋅Kim, Sun⋅Graves, Barbara J and Graves, Barbara J
Cancer Research, vol. 72, (no. 8 Supplement), pp. 3090, 2012-04-15. | Journal Article