213 Publications (Page 8 of 9)
2009
IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease
Staschke, Kirk⋅Staschke, Kirk A⋅Dong, Sucai⋅Dong, Sucai⋅Saha, Joy⋅Saha, Joy⋅Zhao, Jingyong⋅Zhao, Jingyong⋅Brooks, Nathan⋅Brooks, Nathan A⋅Hepburn, Deena L⋅Hepburn, Deena⋅Xia, Jinqi⋅Xia, Jinqi⋅Gulen, Muhammet F⋅Gulen, Muhammet⋅Kang, Zizhen⋅Kang, Zizhen⋅Altuntas, Cengiz⋅Altuntas, Cengiz Z⋅Tuohy, Vincent K⋅Tuohy, Vincent⋅Gilmour, Raymond⋅Gilmour, Raymond⋅Li, Xiaoxia⋅Li, Xiaoxia⋅Na, Songqing and Na, Songqing
The Journal of Immunology, vol. 183, (no. 1), pp. 577, 20090701. | Journal Article
 
IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease. The Journal of Immunology
. | Journal Article
2008
Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation
Rekhter, M.⋅Staschke, K.⋅Estridge, T.⋅Rutherford, P.⋅Jackson, N.⋅Gifford-Moore, D.⋅Foxworthy, P.⋅Reidy, C.⋅Huang, X.-d.⋅Kalbfleisch, M.⋅Hui, K.⋅Kuo, M.-S.⋅Gilmour, R. and Vlahos, C.J.
Biochemical and Biophysical Research Communications, vol. 367, pp. 642-648. | Journal Article
 
Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation. Biochemical and Biophysical Research Communications
. | Journal Article
 
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF?B activation
Xiao, Hui⋅Xiao, H.⋅Qian, W.⋅Qian, Wen⋅Staschke, K.⋅Staschke, Kirk⋅Qian, Y.⋅Qian, Youcun⋅Cui, Grace⋅Cui, G.⋅Deng, Li⋅Deng, L.⋅Ehsani, M.⋅Ehsani, Mariam⋅Wang, X.⋅Wang, Xiliang⋅Qian, Yue-Wei⋅Qian, Y.-W.⋅Chen, Zhijian J⋅Chen, Z.J.⋅Gilmour, Raymond⋅Gilmour, R.⋅Jiang, Zhengfan⋅Jiang, Z.⋅Li, X. and Li, Xiaoxia
Journal of Biological Chemistry, vol. 283, pp. 14654-14664. | Journal Article
 
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappa B activation. Journal of Biological Chemistry
. | Journal Article
 
Phosphorylation of eIF2 Directs ATF5 Translational Control in Response to Diverse Stress Conditions
Zhou, Donghui⋅Zhou, Donghui⋅Palam, LReddy⋅Palam, L.⋅Jiang, Li⋅Jiang, Li⋅Narasimhan, Jana⋅Narasimhan, Jana⋅Staschke, Kirk A⋅Staschke, Kirk⋅Wek, Ronald and Wek, Ronald
Journal of Biological Chemistry, vol. 283, (no. 11), pp. 7073, 20080314. | Journal Article
 
Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions. Journal of Biological Chemistry
. | Journal Article
2007
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity
Tae, W.K.⋅Staschke, K.⋅Bulek, K.⋅Yao, J.⋅Peters, K.⋅Oh, K.-H.⋅Vandenburg, Y.⋅Xiao, H.⋅Qian, W.⋅Hamilton, T.⋅Min, B.⋅Sen, G.⋅Gilmour, R. and Li, X.
Journal of Experimental Medicine, vol. 204, pp. 1025-1036. | Journal Article
 
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity. Journal of Experimental Medicine
. | Journal Article
 
A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication
Sklan, E.H.⋅Staschke, K.⋅Oakes, T.M.⋅Elazar, M.⋅Winters, M.⋅Aroeti, B.⋅Danieli, T. and Glenn, J.S.
Journal of Virology, vol. 81, pp. 11096-11105. | Journal Article
 
Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication?
Huang, Y.⋅Staschke, K.⋅De Francesco, R. and Tan, S.-L.
Virology, vol. 364, pp. 1-9. | Journal Article
 
Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication? Virology
. | Journal Article
2006
A putative Rab GTPase-activating protein binds hepatitis C virus NS5A and mediates viral replication. Hepatology
. | Journal Article
2004
Dimerization Is Required for Activation of eIF2 Kinase Gcn2 in Response to Diverse Environmental Stress Conditions
Narasimhan, J.⋅Narasimhan, Jana⋅Staschke, KA⋅Staschke, Kirk⋅Wek, Ronald and Wek, Ronald
Journal of Biological Chemistry, vol. 279, (no. 22), pp. 22832, 20040528. | Journal Article
 
Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions. Journal of Biological Chemistry
. | Journal Article
2003
Regulation of eIF2 kinases in response to endoplasmic reticulum and nutritional stresses. The FASEB Journal
. | Journal Article
2002
Comparative characterization of two DEAD-box RNA helicases in superfamily II: Human translation-initiation factor 4A and hepatitis C virus non-structural protein 3 (NS3) helicase
Du, M.X.⋅Johnson, R.B.⋅Sun, X.-L.⋅Staschke, K.A.⋅Colacino, J. and Wang, Q.M.
Biochemical Journal, vol. 363, pp. 147-155. | Journal Article
 
Oligomerization and cooperative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase
Wang, Q May⋅Wang, QM⋅Wang, Q.M.⋅Hockman, Michelle A⋅Hockman, MA⋅Hockman, M.A.⋅Staschke, K.⋅Staschke, K.⋅Staschke, Kirk⋅Johnson, R.B.⋅Johnson, RB⋅Johnson, Robert B⋅Case, K.A.⋅Case, KA⋅Case, Katharine A⋅Lu, J.⋅Lu, Jirong⋅Lu, J.⋅Parsons, S.⋅Parsons, Steve⋅Parsons, S.⋅Zhang, F.⋅Zhang, F.⋅Zhang, Faming⋅Rathnachalam, R.⋅Rathnachalam, Radhakrishnan⋅Rathnachalam, R.⋅Kirkegaard, K.⋅Kirkegaard, Karla⋅Kirkegaard, Karla⋅Colacino, JM⋅Colacino, J.M. and Colacino, Joseph M
Journal of Virology, vol. 76, pp. 3865-3872. | Journal Article
2001
Drug discovery and development of antiviral agents for the treatment of chronic hepatitis B virus infection.
Staschke, K.A. and Colacino, J.M.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques, vol. Spec No, pp. 111-183. | Journal Article
 
Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2 alpha (elF2 alpha) European Journal of Biochemistry
. | Journal Article
 
Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2α (eIF2α)
Vattem, Krishna M⋅Vattem, Krishna M⋅Staschke, Kirk A⋅Staschke, Kirk A⋅Zhu, Shuhao⋅Zhu, Shuhao⋅Wek, Ronald C and Wek, Ronald C
European Journal of Biochemistry, vol. 268, (no. 4), pp. 1153, 2001-02-00. | Journal Article
 
Mechanism of activation of the double-stranded-RNA-dependent protein kinase PKR: Role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2)
Vattem, Krishna M⋅Vattem, K.M.⋅Staschke, Kirk A⋅Staschke, K.A.⋅Wek, R.C. and Wek, Ronald C
European Journal of Biochemistry, vol. 268, pp. 3674-3684. | Journal Article
 
Mechanism of activation of the double-stranded-RNA-dependent protein kinase PKR - Role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (elF2) European Journal of Biochemistry
. | Journal Article
1999
Approaches and strategies for the treatment of influenza virus infections
Colacino, J.M.⋅Staschke, K.A. and Laver, W.G.
Antiviral Chemistry and Chemotherapy, vol. 10, pp. 155-185. | Journal Article