44 Publications (Page 1 of 2)
2024
Role of FoxP3+ Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy. Human Gene Therapy
. | Journal Article
2023
Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion. Human Gene Therapy
Rana, JyotiMarsic, DamienZou, ChenhuiMelero, Maite MunozLi, XinKondratov, OleksandrLi, Ningde Yong, YpeZolotukhin, Sergei and Biswas, Moanaro
. | Journal Article
 
Sweeten the deal: Glycopolymer-based engineering to modulate autoreactive T cell responses. Molecular Therapy
. | Journal Article
2022
Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies. Cellular Immunology
. | Journal Article
2021
B cell activating factor modulates the factor VIII immune response in hemophilia A
Doshi, Bhavya SRana, JyotiCastaman, GiancarloShaheen, Mostafa AKaczmarek, RadoslawButterfield, John S SMeeks, Shannon LLeissinger, CindyBiswas, Moanaro and Arruda, Valder R
Journal of Clinical Investigation. | Journal Article
2020
B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin.
M, BiswasB, PalaschakSRP, KumarJ, Rana and DM, Markusic
Frontiers in immunology. | Journal Article
 
Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity.
M, BiswasBiswas, MoanaroD, MarsicMarsic, DamienN, LiLi, NingC, ZouZou, ChenhuiGonzalez-Aseguinolaza, GloriaG, Gonzalez-AseguinolazaZolotukhin, IreneI, ZolotukhinSRP, KumarKumar, Sandeep R PJ, RanaRana, JyotiJSS, ButterfieldButterfield, John S SKondratov, OleksandrO, Kondratovde Jong, Ype PJong YPRW, HerzogHerzog, Roland WZolotukhin, Sergei and S, Zolotukhin
Molecular therapy. Methods & clinical development. | Journal Article
 
Neutralizing the Neutralizers in AAV Gene Therapy.
RW, Herzog and M, Biswas
Molecular therapy : the journal of the American Society of Gene Therapy. | Journal Article
 
Regulatory T cell therapy: Current and future design perspectives.
J, Rana and M, Biswas
Cellular immunology. | Journal Article
 
Role of orally induced regulatory T cells in immunotherapy and tolerance.
TB, BertoliniM, BiswasC, TerhorstH, DaniellRW, Herzog and AR, Piñeros
Cellular immunology. | Journal Article
2019
Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer
Herzog, Roland WHerzog, R.W.Cooper, M.Cooper, MarioPerrin, George QPerrin, G.Q.Biswas, M.Biswas, MoanaroMartino, A.T.Martino, Ashley TMorel, LaurenceMorel, L.Terhorst, C.Terhorst, CoxHoffman, B.E. and Hoffman, Brad E
Cellular Immunology, vol. 342, pp. 103682, August 2019. | Journal Article
 
Reprogrammed CD4 + T Cells That Express FoxP3 + Control Inhibitory Antibody Formation in Hemophilia A Mice
Herzog, Roland WKuteyeva, VeronicaSaboungi, RaniaTerhorst, Cox and Biswas, Moanaro
Frontiers in immunology, vol. 10, pp. 274, 2019-00-00. | Journal Article
 
TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer
Butterfield, John S.SBiswas, MoanaroShirley, Jamie LKumar, Sandeep R.PSherman, AlexandraTerhorst, CoxLing, Chen and Herzog, Roland W
Human Gene Therapy Methods, vol. 30, (no. 3), pp. 92, 2019-06-01. | Journal Article
 
Toll-like Receptor 9 Activation Accelerates Inhibitor Formation in Response to Factor VIII
Kaczmarek, RadoslawSherman, AlexandraBiswas, Moanaro and Herzog, Roland W
Blood, vol. 134, (no. Supplement_1), pp. 1113, 2019-11-13. | Journal Article
2018
Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice
Kwon, Kwang‐ChulSherman, AlexandraChang, Wan‐JungKamesh, AdityaBiswas, MoanaroHerzog, Roland W and Daniell, Henry
Plant Biotechnology Journal, vol. 16, (no. 6), pp. 1160, June 2018. | Journal Article
 
Gene Therapy With Regulatory T Cells: A Beneficial Alliance
Biswas, MoanaroKumar, Sandeep R PTerhorst, Cox and Herzog, Roland W
Frontiers in immunology, vol. 9, pp. 554, 2018-00-00. | Journal Article
 
Tolerance induction in hemophilia: innovation and accomplishments
Sherman, AlexandraBiswas, Moanaro and Herzog, Roland
Current Opinion in Hematology, vol. 25, (no. 5), pp. 372, 2018-July-9. | Journal Article
2017
CD8 T cells protect adult naive mice from JEV-induced morbidity via lytic function
Jain, NidhiOswal, NeelamChawla, Amanpreet SinghAgrawal, TanviBiswas, MoanaroVrati, SudhanshuRath, SatyajitGeorge, AnnaBal, Vineeta and Medigeshi, Guruprasad R
PLoS neglected tropical diseases, vol. 11, (no. 2), pp. e0005329, 2017-02-00. | Journal Article
 
Combination therapy for inhibitor reversal in haemophilia A using monoclonal anti-CD20 and rapamycin
Biswas, MoanaroBiswas, M.Biswas, MoanaroRogers, Geoffrey LRogers, Geoffrey LRogers, G.L.Sherman, AlexandraSherman, A.Sherman, AlexandraByrne, B.J.Byrne, Barry JByrne, Barry JMarkusic, D.M.Markusic, David MMarkusic, David MJiang, H.Jiang, HaiyanJiang, HaiyanHerzog, Roland WHerzog, Roland W and Herzog, R.W.
Thrombosis and Haemostasis, vol. 117, (no. 1), pp. 43, 20170000. | Journal Article
 
Genetically engineered oncolytic Newcastle disease virus mediates cytolysis of prostate cancer stem like cells
Raghunath, ShobanaPudupakam, Raghavendra SumanthAllen, AdriaBiswas, Moanaro and Sriranganathan, Nammalwar
Journal of Biotechnology, vol. 260, pp. 97, 2017-10-20. | Journal Article
 
Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B Cells
Wang, XiaomeiWang, X.Herzog, R.W.Herzog, Roland WByrne, B.J.Byrne, Barry JKumar, S.R.P.Kumar, Sandeep R PZhou, Q.Zhou, QiBuchholz, C.J.Buchholz, Christian JBiswas, M. and Biswas, Moanaro
Molecular therapy. Methods & clinical development, vol. 5, (no. C), pp. 82, 2017-Jun-16. | Journal Article
 
Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A
Sherman, AlexandraBiswas, Moanaro and Herzog, Roland W
Frontiers in immunology, vol. 8, pp. 1604, 2017-00-00. | Journal Article
 
Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells
Rogers, Geoffrey LRogers, G.L.Rogers, Geoffrey LShirley, Jamie LShirley, Jamie LShirley, J.L.Zolotukhin, IreneZolotukhin, IreneZolotukhin, I.Kumar, Sandeep R PKumar, Sandeep R PKumar, S.R.P.Sherman, A.Sherman, AlexandraSherman, AlexandraPerrin, George QPerrin, George QPerrin, G.Q.Hoffman, B.E.Hoffman, Brad EHoffman, Brad ESrivastava, ArunSrivastava, A.Srivastava, ArunBasner-Tschakarjan, EtienaBasner-Tschakarjan, EtienaBasner-Tschakarjan, E.Wallet, Mark AWallet, Mark AWallet, M.A.Terhorst, CoxTerhorst, C.Terhorst, CoxBiswas, MoanaroBiswas, M.Biswas, MoanaroHerzog, R.W.Herzog, Roland W and Herzog, Roland W
Blood, vol. 129, (no. 24), pp. 3195, 2017-06-15. | Journal Article
2016
Clinical development of gene therapy: results and lessons from recent successes
Kumar, Sandeep RpKumar, Sandeep RpMarkusic, David MMarkusic, David MBiswas, MoanaroBiswas, MoanaroHigh, Katherine AHigh, Katherine AHerzog, Roland W and Herzog, Roland W
Molecular therapy. Methods & clinical development, vol. 3, (no. C), pp. 16034, 2016-00-00. | Journal Article
 
Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transfer
Perrin, George QZolotukhin, IreneSherman, AlexandraBiswas, Moanarode Jong, Ype PTerhorst, CoxDavidoff, Andrew M and Herzog, Roland W
Molecular therapy. Methods & clinical development, vol. 3, (no. C), pp. 16083, 2016-00-00. | Journal Article