44 Publications (Page 1 of 2)
2024
Role of FoxP3+ Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy. Human Gene Therapy
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2023
Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion. Human Gene TherapyRana, Jyoti⋅Marsic, Damien⋅Zou, Chenhui⋅Melero, Maite Munoz⋅Li, Xin⋅Kondratov, Oleksandr⋅Li, Ning⋅de Yong, Ype⋅Zolotukhin, Sergei and Biswas, Moanaro.
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Sweeten the deal: Glycopolymer-based engineering to modulate autoreactive T cell responses. Molecular Therapy
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2022
Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies. Cellular Immunology
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2021
B cell activating factor modulates the factor VIII immune response in hemophilia ADoshi, Bhavya S⋅Rana, Jyoti⋅Castaman, Giancarlo⋅Shaheen, Mostafa A⋅Kaczmarek, Radoslaw⋅Butterfield, John S S⋅Meeks, Shannon L⋅Leissinger, Cindy⋅Biswas, Moanaro and Arruda, Valder RJournal of Clinical Investigation.
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2020
B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin.
M, Biswas⋅B, Palaschak⋅SRP, Kumar⋅J, Rana and DM, Markusic
Frontiers in immunology. | Journal Article
Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity.M, Biswas⋅Biswas, Moanaro⋅D, Marsic⋅Marsic, Damien⋅N, Li⋅Li, Ning⋅C, Zou⋅Zou, Chenhui⋅Gonzalez-Aseguinolaza, Gloria⋅G, Gonzalez-Aseguinolaza⋅Zolotukhin, Irene⋅I, Zolotukhin⋅SRP, Kumar⋅Kumar, Sandeep R P⋅J, Rana⋅Rana, Jyoti⋅JSS, Butterfield⋅Butterfield, John S S⋅Kondratov, Oleksandr⋅O, Kondratov⋅de Jong, Ype P⋅Jong YP⋅RW, Herzog⋅Herzog, Roland W⋅Zolotukhin, Sergei and S, ZolotukhinMolecular therapy. Methods & clinical development.
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Neutralizing the Neutralizers in AAV Gene Therapy.
RW, Herzog and M, Biswas
Molecular therapy : the journal of the American Society of Gene Therapy. | Journal Article
Regulatory T cell therapy: Current and future design perspectives.
J, Rana and M, Biswas
Cellular immunology. | Journal Article
Role of orally induced regulatory T cells in immunotherapy and tolerance.
TB, Bertolini⋅M, Biswas⋅C, Terhorst⋅H, Daniell⋅RW, Herzog and AR, Piñeros
Cellular immunology. | Journal Article
2019
Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transferHerzog, Roland W⋅Herzog, R.W.⋅Cooper, M.⋅Cooper, Mario⋅Perrin, George Q⋅Perrin, G.Q.⋅Biswas, M.⋅Biswas, Moanaro⋅Martino, A.T.⋅Martino, Ashley T⋅Morel, Laurence⋅Morel, L.⋅Terhorst, C.⋅Terhorst, Cox⋅Hoffman, B.E. and Hoffman, Brad ECellular Immunology, vol. 342, pp. 103682, August 2019.
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Reprogrammed CD4 + T Cells That Express FoxP3 + Control Inhibitory Antibody Formation in Hemophilia A MiceHerzog, Roland W⋅Kuteyeva, Veronica⋅Saboungi, Rania⋅Terhorst, Cox and Biswas, MoanaroFrontiers in immunology, vol. 10, pp. 274, 2019-00-00.
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TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene TransferButterfield, John S.S⋅Biswas, Moanaro⋅Shirley, Jamie L⋅Kumar, Sandeep R.P⋅Sherman, Alexandra⋅Terhorst, Cox⋅Ling, Chen and Herzog, Roland WHuman Gene Therapy Methods, vol. 30, (no. 3), pp. 92, 2019-06-01.
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Toll-like Receptor 9 Activation Accelerates Inhibitor Formation in Response to Factor VIIIKaczmarek, Radoslaw⋅Sherman, Alexandra⋅Biswas, Moanaro and Herzog, Roland WBlood, vol. 134, (no. Supplement_1), pp. 1113, 2019-11-13.
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2018
Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A miceKwon, Kwang‐Chul⋅Sherman, Alexandra⋅Chang, Wan‐Jung⋅Kamesh, Aditya⋅Biswas, Moanaro⋅Herzog, Roland W and Daniell, HenryPlant Biotechnology Journal, vol. 16, (no. 6), pp. 1160, June 2018.
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Gene Therapy With Regulatory T Cells: A Beneficial AllianceBiswas, Moanaro⋅Kumar, Sandeep R P⋅Terhorst, Cox and Herzog, Roland WFrontiers in immunology, vol. 9, pp. 554, 2018-00-00.
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Tolerance induction in hemophilia: innovation and accomplishmentsSherman, Alexandra⋅Biswas, Moanaro and Herzog, RolandCurrent Opinion in Hematology, vol. 25, (no. 5), pp. 372, 2018-July-9.
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2017
CD8 T cells protect adult naive mice from JEV-induced morbidity via lytic functionJain, Nidhi⋅Oswal, Neelam⋅Chawla, Amanpreet Singh⋅Agrawal, Tanvi⋅Biswas, Moanaro⋅Vrati, Sudhanshu⋅Rath, Satyajit⋅George, Anna⋅Bal, Vineeta and Medigeshi, Guruprasad RPLoS neglected tropical diseases, vol. 11, (no. 2), pp. e0005329, 2017-02-00.
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Combination therapy for inhibitor reversal in haemophilia A using monoclonal anti-CD20 and rapamycinBiswas, Moanaro⋅Biswas, M.⋅Biswas, Moanaro⋅Rogers, Geoffrey L⋅Rogers, Geoffrey L⋅Rogers, G.L.⋅Sherman, Alexandra⋅Sherman, A.⋅Sherman, Alexandra⋅Byrne, B.J.⋅Byrne, Barry J⋅Byrne, Barry J⋅Markusic, D.M.⋅Markusic, David M⋅Markusic, David M⋅Jiang, H.⋅Jiang, Haiyan⋅Jiang, Haiyan⋅Herzog, Roland W⋅Herzog, Roland W and Herzog, R.W.Thrombosis and Haemostasis, vol. 117, (no. 1), pp. 43, 20170000.
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Genetically engineered oncolytic Newcastle disease virus mediates cytolysis of prostate cancer stem like cellsRaghunath, Shobana⋅Pudupakam, Raghavendra Sumanth⋅Allen, Adria⋅Biswas, Moanaro and Sriranganathan, NammalwarJournal of Biotechnology, vol. 260, pp. 97, 2017-10-20.
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Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B CellsWang, Xiaomei⋅Wang, X.⋅Herzog, R.W.⋅Herzog, Roland W⋅Byrne, B.J.⋅Byrne, Barry J⋅Kumar, S.R.P.⋅Kumar, Sandeep R P⋅Zhou, Q.⋅Zhou, Qi⋅Buchholz, C.J.⋅Buchholz, Christian J⋅Biswas, M. and Biswas, MoanaroMolecular therapy. Methods & clinical development, vol. 5, (no. C), pp. 82, 2017-Jun-16.
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Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia ASherman, Alexandra⋅Biswas, Moanaro and Herzog, Roland WFrontiers in immunology, vol. 8, pp. 1604, 2017-00-00.
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Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cellsRogers, Geoffrey L⋅Rogers, G.L.⋅Rogers, Geoffrey L⋅Shirley, Jamie L⋅Shirley, Jamie L⋅Shirley, J.L.⋅Zolotukhin, Irene⋅Zolotukhin, Irene⋅Zolotukhin, I.⋅Kumar, Sandeep R P⋅Kumar, Sandeep R P⋅Kumar, S.R.P.⋅Sherman, A.⋅Sherman, Alexandra⋅Sherman, Alexandra⋅Perrin, George Q⋅Perrin, George Q⋅Perrin, G.Q.⋅Hoffman, B.E.⋅Hoffman, Brad E⋅Hoffman, Brad E⋅Srivastava, Arun⋅Srivastava, A.⋅Srivastava, Arun⋅Basner-Tschakarjan, Etiena⋅Basner-Tschakarjan, Etiena⋅Basner-Tschakarjan, E.⋅Wallet, Mark A⋅Wallet, Mark A⋅Wallet, M.A.⋅Terhorst, Cox⋅Terhorst, C.⋅Terhorst, Cox⋅Biswas, Moanaro⋅Biswas, M.⋅Biswas, Moanaro⋅Herzog, R.W.⋅Herzog, Roland W and Herzog, Roland WBlood, vol. 129, (no. 24), pp. 3195, 2017-06-15.
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2016
Clinical development of gene therapy: results and lessons from recent successesKumar, Sandeep Rp⋅Kumar, Sandeep Rp⋅Markusic, David M⋅Markusic, David M⋅Biswas, Moanaro⋅Biswas, Moanaro⋅High, Katherine A⋅High, Katherine A⋅Herzog, Roland W and Herzog, Roland WMolecular therapy. Methods & clinical development, vol. 3, (no. C), pp. 16034, 2016-00-00.
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Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transferPerrin, George Q⋅Zolotukhin, Irene⋅Sherman, Alexandra⋅Biswas, Moanaro⋅de Jong, Ype P⋅Terhorst, Cox⋅Davidoff, Andrew M and Herzog, Roland WMolecular therapy. Methods & clinical development, vol. 3, (no. C), pp. 16083, 2016-00-00.
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