213 Publications (Page 2 of 9)
2017
Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions
Culleton, Sara P.⋅Kanginakudru, Sriramana⋅DeSmet, Marsha⋅Gilson, Timra⋅Xie, Fang⋅Wu, Shwu-Yuan⋅Chiang, Cheng-Ming⋅Qi, Guihong⋅Wang, Mu and Androphy, Elliot J.
Journal of Virology, vol. 91. | Journal Article
 
SMN deficiency negatively impacts red pulp macrophages and spleen development in mouse models of spinal muscular atrophy
Khairallah, Marie-Therese⋅Khairallah, Marie-Therese⋅Astroski, Jacob⋅Astroski, Jacob⋅Custer, Sarah K⋅Custer, Sarah K⋅Androphy, Elliot J⋅Androphy, Elliot J⋅Franklin, Craig L⋅Franklin, Craig L⋅Lorson, Christian L and Lorson, Christian L
Human molecular genetics, vol. 26, (no. 5), pp. 941, 2017-Mar-01. | Journal Article
2016
Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells
Custer, Sara K⋅Custer, Sara K.⋅Gilson, Timra D⋅Gilson, Timra D.⋅Li, Hongxia⋅Li, Hongxia⋅Todd, A Gary⋅Todd, A. Gary⋅Astroski, Jacob W⋅Astroski, Jacob W.⋅Lin, Hai⋅Lin, Hai⋅Liu, Yunlong⋅Liu, Yunlong⋅Androphy, Elliot J and Androphy, Elliot J.
PLOS ONE, vol. 11, pp. e0163954. | Journal Article
 
Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53
DasGupta, Twishasri⋅DasGupta, Twishasri⋅Nweze, Emeka I⋅Nweze, Emeka I⋅Yue, Hong⋅Yue, Hong⋅Wang, Liming⋅Wang, Liming⋅Jin, Jessica⋅Jin, Jessica⋅Ghosh, Santosh K⋅Ghosh, Santosh K⋅Kawsar, Hameem I⋅Kawsar, Hameem I⋅Zender, Chad⋅Zender, Chad⋅Androphy, Elliot J⋅Androphy, Elliot J⋅Weinberg, Aaron⋅Weinberg, Aaron⋅McCormick, Thomas S⋅McCormick, Thomas S⋅Jin, Ge and Jin, Ge
Oncotarget, vol. 7, (no. 19), pp. 27444, 2016-May-10. | Journal Article
 
ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice
Abera, Mahlet B⋅Abera, Mahlet B⋅Xiao, Jingbo⋅Xiao, Jingbo⋅Nofziger, Jonathan⋅Nofziger, Jonathan⋅Titus, Steve⋅Titus, Steve⋅Southall, Noel⋅Southall, Noel⋅Zheng, Wei⋅Zheng, Wei⋅Moritz, Kasey E⋅Moritz, Kasey E⋅Ferrer, Marc⋅Ferrer, Marc⋅Cherry, Jonathan J⋅Cherry, Jonathan J⋅Androphy, Elliot J⋅Androphy, Elliot J⋅Wang, Amy⋅Wang, Amy⋅Xu, Xin⋅Xu, Xin⋅Austin, Christopher⋅Austin, Christopher⋅Fischbeck, Kenneth H⋅Fischbeck, Kenneth H⋅Marugan, Juan J⋅Marugan, Juan J⋅Burnett, Barrington G and Burnett, Barrington G
JCI insight, vol. 1, (no. 19), pp. e88427, 2016-11-17. | Journal Article
 
Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors
Rietz, Anne⋅Rietz, Anne⋅Rietz, Anne⋅Petrov, Dino P⋅Petrov, Dino P⋅Petrov, Dino P⋅Bartolowits, Matthew⋅Bartolowits, Matthew⋅Bartolowits, Matthew⋅DeSmet, Marsha⋅DeSmet, Marsha⋅DeSmet, Marsha⋅Davisson, V Jo⋅Davisson, V Jo⋅Davisson, V Jo⋅Androphy, Elliot J⋅Androphy, Elliot J and Androphy, Elliot J
PloS one, vol. 11, (no. 2), pp. e0149845, 2016-00-00. | Journal Article
 
Small Molecules in Development for the Treatment of Spinal Muscular Atrophy.
Calder, Alyssa N⋅Androphy, Elliot J and Hodgetts, Kevin J
Journal of medicinal chemistry, August 4, 2016. | Journal Article
 
The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2
DeSmet, Marsha⋅DeSmet, Marsha⋅DeSmet, Marsha⋅DeSmet, Marsha⋅Kanginakudru, Sriramana⋅Kanginakudru, Sriramana⋅Kanginakudru, Sriramana⋅Kanginakudru, Sriramana⋅Rietz, Anne⋅Rietz, Anne⋅Rietz, Anne⋅Rietz, Anne⋅Wu, Wai-Hong⋅Wu, Wai-Hong⋅Wu, Wai-Hong⋅Wu, Wai-Hong⋅Roden, Richard⋅Roden, Richard⋅Roden, Richard⋅Roden, Richard⋅Androphy, Elliot J⋅Androphy, Elliot J⋅Androphy, Elliot J and Androphy, Elliot J.
PLOS Pathogens, vol. 12, pp. e1005934. | Journal Article
2015
Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication
Kanginakudru, Sriramana⋅DeSmet, Marsha⋅Thomas, Yanique⋅Morgan, Iain and Androphy, Elliot
Virology, vol. 478, pp. 136, 2015. | Journal Article
 
α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth
Li, Hongxia⋅Custer, Sara K⋅Gilson, Timra⋅Hao, Le Thi⋅Beattie, Christine E and Androphy, Elliot J
Human molecular genetics, vol. 24, (no. 25), pp. 7307, 2015-Dec-20. | Journal Article
2014
Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy
Molecular and Cellular Neuroscience. | Journal Article
2013
Acetylation of conserved lysines in bovine papillomavirus E2 by p300
Quinlan, E.J.⋅Culleton, S.P.⋅Wu, S.-Y.⋅Chiang, C.-M. and Androphy, E.J.
Journal of Virology, vol. 87, pp. 1497-1507. | Journal Article
 
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation.
Lakhter, Alexander J⋅Lakhter, Alexander J⋅Sahu, Ravi P⋅Sahu, Ravi P⋅Sun, Yang⋅Sun, Yang⋅Kaufmann, William K⋅Kaufmann, William K⋅Androphy, Elliot J⋅Androphy, Elliot J⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Naidu, Samisubbu R and Naidu, Samisubbu R
The Journal of investigative dermatology, vol. 133, (no. 9), pp. 2247-54, 2013/Sep. | Journal Article
 
COPI transport complexes bind to specific RNAs in neuronal cells
Todd, Adrian G⋅Todd, A.G.⋅Lin, Hai⋅Lin, H.⋅Ebert, A.D.⋅Ebert, Allison D⋅Liu, Yunlong⋅Liu, Y.⋅Androphy, E.J. and Androphy, Elliot J
Human Molecular Genetics, vol. 22, pp. 729-736. | Journal Article
 
Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle proteina α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy
Custer, Sara K⋅Custer, S.K.⋅Todd, A.G.⋅Todd, Adrian G⋅Singh, Natalia N⋅Singh, N.N.⋅Androphy, Elliot J and Androphy, E.J.
Human Molecular Genetics, vol. 22, pp. 4043-4052. | Journal Article
 
Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds.
Cherry, Jonathan J⋅Osman, Erkan Y⋅Evans, Matthew C⋅Choi, Sungwoon⋅Xing, Xuechao⋅Cuny, Greg⋅Glicksman, Marcie A⋅Lorson, Christian and Androphy, Elliot J
EMBO molecular medicine, vol. 5, (no. 7), pp. 1035-50, 2013/Jul. | Journal Article
 
Genomic instability: Ada3 and HPV E6-acetyltransferase connections?
Androphy, E.J.
Cell Cycle, vol. 12, pp. 13-14. | Journal Article
 
Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function.
Cherry, Jonathan J⋅Cherry, Jonathan J⋅Rietz, Anne⋅Rietz, Anne⋅Malinkevich, Anna⋅Malinkevich, Anna⋅Liu, Yuqi⋅Liu, Yuqi⋅Xie, Meng⋅Xie, Meng⋅Bartolowits, Matthew⋅Bartolowits, Matthew⋅Davisson, V Jo⋅Davisson, V J⋅Baleja, James D⋅Baleja, James D⋅Androphy, Elliot J and Androphy, Elliot J
PloS one, vol. 8, (no. 12), pp. e84506, 2013. | Journal Article
2012
Identification of novel compounds that increase SMN protein levels using an improved SMN2 reporter cell assay.
Cherry, Jonathan J⋅Evans, Matthew C⋅Ni, Jake⋅Cuny, Greg⋅Glicksman, Marcie A and Androphy, Elliot J
Journal of biomolecular screening, vol. 17, (no. 4), pp. 481-95, 2012/Apr. | Journal Article
 
PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.
Naidu, Samisubbu R⋅Lakhter, Alexander J and Androphy, Elliot J
Cell cycle (Georgetown, Tex.), vol. 11, (no. 14), pp. 2717-28, 2012/Jul/15. | Journal Article
 
The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3
Love, Ian M⋅Love, I.M.⋅Sekaric, Pedja⋅Sekaric, P.⋅Shi, Dingding⋅Shi, D.⋅Grossman, Steven⋅Grossman, S.R.⋅Androphy, E.J. and Androphy, Elliot J
Cell Cycle, vol. 11, pp. 2458-2466. | Journal Article
 
Therapeutic strategies for the treatment of spinal muscular atrophy
Cherry, J.J. and Androphy, E.J.
Future Medicinal Chemistry, vol. 4, pp. 1733-1750. | Journal Article
 
Transcriptional Repression of E-Cadherin by Human Papillomavirus Type 16 E6
D'Costa, Zarina J⋅D’Costa, Z.J.⋅Jolly, Carol⋅Jolly, C.⋅Androphy, Elliot J⋅Androphy, E.J.⋅Mercer, Andrew A⋅Mercer, A.⋅Matthews, Charles M⋅Matthews, C.M.⋅Hibma, Merilyn and Hibma, M.H.
PLoS ONE, vol. 7. | Journal Article
2011
Differential regulation of the SMN2 gene by individual HDAC proteins.
Evans, Matthew C⋅Cherry, Jonathan J and Androphy, Elliot J
Biochemical and biophysical research communications, vol. 414, (no. 1), pp. 25-30, 2011/Oct/14. | Journal Article
 
Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
Xiao, Jingbo⋅Marugan, Juan⋅Zheng, Wei⋅Titus, Steve⋅Southall, Noel⋅Cherry, Jonathan J⋅Evans, Matthew⋅Androphy, Elliot J and Austin, Christopher P
Journal of medicinal chemistry, vol. 54, (no. 18), pp. 6215-33, 2011/Sep/22. | Journal Article