97 Publications (Page 1 of 4)
2023
Iridium(iii) polypyridine artificial metalloenzymes with tunable photophysical properties: a new platform for visible light photocatalysis in aqueous solution
Liu, BingqingZubi, Yasmine S and Lewis, Jared C
Dalton Transactions, vol. 52, (no. 16), pp. 5034-5038, 2023. | Journal Article
2022
Controlling the optical and catalytic properties of artificial metalloenzyme photocatalysts using chemogenetic engineering
Zubi, Yasmine S.Zubi, Yasmine SLiu, BingqingLiu, BingqingGu, YifanGu, YifanSahoo, DipankarSahoo, DipankarLewis, Jared C. and Lewis, Jared C
Chemical Science, vol. 13, (no. 5), pp. 1459-1468, 2022. | Journal Article
 
Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches
Zubi, Yasmine SZubi, Yasmine SLi, YingLi, YingHunt, Andrew CHunt, Andrew CLiu, BingqingLiu, BingqingJewett, Michael CJewett, Michael CLewis, Jared C and Lewis, Jared C
Nature Communications, vol. 13, (no. 1), 2022. | Journal Article
2021
Flavin-dependent halogenases catalyze enantioselective olefin halocyclization
Fisher, Brian FJiang, Yuhua and Lewis, Jared C
Nature Communications, vol. 12, (no. 1), 2021. | Journal Article
2020
Catalytic Behavior of Mono-N -Protected Amino-Acid Ligands in Ligand-Accelerated C−H Activation by Palladium(II)
Salazar, Chase AGair, Joseph JFlesch, Kaylin NGuzei, Ilia ALewis, Jared C and Stahl, Shannon S
Angewandte Chemie, 2020-04-08. | Journal Article
 
Catalytic Behavior of Mono-N-Protected Amino-Acid Ligands in Ligand-Accelerated C-H Activation by Palladium(II)
Salazar, Chase AGair, Joseph JFlesch, Kaylin NGuzei, Ilia ALewis, Jared C and Stahl, Shannon S
Angewandte Chemie (International ed. in English), 2020-Mar-20. | Journal Article
2019
A High-Throughput Method for Directed Evolution of NAD(P)+-Dependent Dehydrogenases for the Reduction of Biomimetic Nicotinamide Analogues
Huang, RuiChen, HuiUpp, David MLewis, Jared C and Zhang, Yi-Heng P. Job
ACS Catalysis, vol. 9, (no. 12), pp. 11719, 2019-12-06. | Journal Article
 
Beyond the Second Coordination Sphere: Engineering Dirhodium Artificial Metalloenzymes To Enable Protein Control of Transition Metal Catalysis
Lewis, Jared C
Accounts of chemical research, vol. 52, (no. 3), pp. 584, 2019-Mar-19. | Journal Article
 
Crystal Structure and Conformational Dynamics of Pyrococcus furiosus Prolyl Oligopeptidase
Ellis-Guardiola, KenRui, HuanBeckner, Ryan LSrivastava, PoonamSukumar, NarayanasamiRoux, Benoît and Lewis, Jared C
Biochemistry, vol. 58, (no. 12), pp. 1626, 2019-Mar-26. | Journal Article
 
Di-Palladium Complexes are Active Catalysts for Mono-N-Protected Amino Acid-Accelerated Enantioselective C–H Functionalization
Gair, Joseph JHaines, Brandon EFilatov, Alexander SMusaev, Djamaladdin G and Lewis, Jared C
ACS Catalysis, vol. 9, (no. 12), pp. 11397, 2019-12-06. | Journal Article
 
Site-Selective C-H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling
Fisher, Brian FSnodgrass, Harrison MJones, Krysten AAndorfer, Mary C and Lewis, Jared C
ACS central science, vol. 5, (no. 11), pp. 1856, 2019-Nov-27. | Journal Article
 
Synthesis, Characterization, and Theoretical Investigation of a Transition State Analogue for Proton Transfer during C–H Activation by a Rhodium-Pincer Complex
Gair, Joseph JQiu, YehaoKhade, Rahul LChan, Natalie HFilatov, Alexander SZhang, Yong and Lewis, Jared C
Organometallics, vol. 38, (no. 7), pp. 1412, 2019-04-08. | Journal Article
2018
Enantioselective Desymmetrization of Methylenedianilines via Enzyme-Catalyzed Remote Halogenation
Payne, James TButkovich, Paul HGu, YifanKunze, Kyle NPark, Hyun JuneWang, Duo-Sheng and Lewis, Jared C
Journal of the American Chemical Society, vol. 140, (no. 2), pp. 549, 2018-Jan-17. | Journal Article
 
Evolving artificial metalloenzymes via random mutagenesis
Yang, HaoYang, HaoSwartz, Alan MSwartz, Alan MPark, Hyun JPark, Hyun JuneSrivastava, PoonamSrivastava, PoonamEllis-Guardiola, KenEllis-Guardiola, KenUpp, David MUpp, David MLee, GihoonLee, GihoonBelsare, KetakiBelsare, KetakiGu, YifanGu, YifanZhang, ChenZhang, ChenMoellering, Raymond EMoellering, Raymond ELewis, Jared C and Lewis, Jared C
Nature chemistry, vol. 10, (no. 3), pp. 324, 2018-03-00. | Journal Article
 
Introduction: Biocatalysis in Industry
Hughes, Greg and Lewis, Jared C
Chemical reviews, vol. 118, (no. 1), pp. 3, 2018-01-10. | Journal Article
 
Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis
Andorfer, Mary C and Lewis, Jared C
Annual review of biochemistry, vol. 87, (no. 1), pp. 185, 20180620. | Journal Article
2017
Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.
Andorfer, Mary CBelsare, Ketaki DGirlich, Anna M and Lewis, Jared C
Chembiochem : a European journal of chemical biology, September 6, 2017. | Journal Article
 
Artificial Metalloenzymes: Reaction Scope and Optimization Strategies.
Schwizer, FabianOkamoto, YasunoriHeinisch, TillmannGu, YifanPellizzoni, Michela MLebrun, VincentReuter, RaphaelKöhler, ValentinLewis, Jared C and Ward, Thomas R
Chemical reviews, July 17, 2017. | Journal Article
 
Mono- N -protected amino acid ligands stabilize dimeric palladium(ii) complexes of importance to C-H functionalization
Gair, Joseph JHaines, Brandon EFilatov, Alexander SMusaev, Djamaladdin G and Lewis, Jared C
Chemical science, vol. 8, (no. 8), pp. 5756, 2017-Aug-01. | Journal Article
 
Mono-N-protected amino acid ligands stabilize dimeric palladium(ii) complexes of importance to C–H functionalization† †Electronic supplementary information (ESI) available: Experimental procedures, analytical and spectral characterization data for all new compounds, and crystallographic information files (CIF) for compounds 2, 6a–c, 15, 16, 17, S1.4, and S5.1. CCDC 1544213–1544221. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc01674c
Gair, Joseph JHaines, Brandon EFilatov, Alexander SMusaev, Djamaladdin G and Lewis, Jared C
Chemical Science, vol. 8, (no. 8), pp. 5756, 2017-06-01. | Journal Article
 
Rhodium Complexes of 2,6-Bis(dialkylphosphinomethyl)pyridines: Improved C–H Activation, Expanded Reaction Scope, and Catalytic Direct Arylation
Gair, Joseph JQiu, YehaoChan, Natalie HFilatov, Alexander S and Lewis, Jared C
Organometallics, vol. 36, (no. 24), pp. 4706, 2017-12-26. | Journal Article
 
Selective C-H bond functionalization using repurposed or artificial metalloenzymes.
Upp, David M and Lewis, Jared C
Current opinion in chemical biology, vol. 37, pp. 48-55, January 27, 2017. | Journal Article
 
Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling.
Andorfer, Mary CGrob, Jonathan EHajdin, Christine EChael, Julia RSiuti, PiroLilly, JeremiahTan, Kian L and Lewis, Jared C
ACS catalysis, vol. 7, (no. 3), pp. 1897-1904, March 3, 2017. | Journal Article
2016
A Simple Combinatorial Codon Mutagenesis Method for Targeted Protein Engineering.
Belsare, Ketaki DeepakAndorfer, Mary CCardenas, FridaChael, Julia RPark, Hyun June and Lewis, Jared C
ACS synthetic biology, December 29, 2016. | Journal Article
 
Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H Bonds.
Andorfer, Mary CPark, Hyun JuneVergara-Coll, Jaylie and Lewis, Jared C
Chemical science (Royal Society of Chemistry : 2010), vol. 7, (no. 6), pp. 3720-3729, June 1, 2016. | Journal Article