Research Interests
- Tumor suppressor, p53; oncogene, MDM2; cancer cell biology; pediatric brain cancer; regulation of cell fate decisions; cerebellar development.
Current projects — Elucidating the role of MDM2, a critical negative regulator of the p53 tumor suppressor, in cerebellar development and tumorigenesis; exploiting genetically modified mice in combination with cell culture models to place MDM2 and p53 within the molecular signaling pathways that govern neuronal differentiation and cell fate decisions.