117 Publications (Page 1 of 5)
2022
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Schweighauser, Manuel⋅Schweighauser, Manuel⋅Arseni, Diana⋅Arseni, Diana⋅Bacioglu, Mehtap⋅Bacioglu, Mehtap⋅Huang, Melissa⋅Huang, Melissa⋅Lövestam, Sofia⋅Lövestam, Sofia⋅Shi, Yang⋅Shi, Yang⋅Yang, Yang⋅Yang, Yang⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Kotecha, Abhay⋅Kotecha, Abhay⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Hallinan, Grace I⋅Hallinan, Grace I⋅Newell, Kathy L⋅Newell, Kathy L⋅Tarutani, Airi⋅Tarutani, Airi⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Miyazaki, Masayuki⋅Miyazaki, Masayuki⋅Saito, Yuko⋅Saito, Yuko⋅Yoshida, Mari⋅Yoshida, Mari⋅Hasegawa, Kazuko⋅Hasegawa, Kazuko⋅Lashley, Tammaryn⋅Lashley, Tammaryn⋅Revesz, Tamas⋅Revesz, Tamas⋅Kovacs, Gabor G⋅Kovacs, Gabor G⋅van Swieten, John⋅van Swieten, John⋅Takao, Masaki⋅Takao, Masaki⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Spillantini, Maria G⋅Spillantini, Maria Grazia⋅Ryskeldi-Falcon, Benjamin⋅Ryskeldi-Falcon, Benjamin⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H W and Scheres, Sjors H
Nature, March 28, 2022. | Journal Article
2021
Structure-based classification of tauopathies
Shi, Yang⋅Zhang, Wenjuan⋅Yang, Yang⋅Murzin, Alexey G⋅Falcon, Benjamin⋅Kotecha, Abhay⋅van Beers, Mike⋅Tarutani, Airi⋅Kametani, Fuyuki⋅Garringer, Holly J⋅Vidal, Ruben⋅Hallinan, Grace I⋅Lashley, Tammaryn⋅Saito, Yuko⋅Murayama, Shigeo⋅Yoshida, Mari⋅Tanaka, Hidetomo⋅Kakita, Akiyoshi⋅Ikeuchi, Takeshi⋅Robinson, Andrew C⋅Mann, David M⋅Kovacs, Gabor G⋅Revesz, Tamas⋅Ghetti, Bernardino⋅Hasegawa, Masato⋅Goedert, Michel and Scheres, Sjors H
Nature, vol. 598, (no. 7880), pp. 359-3,363A-363M, Oct 14, 2021. | Journal Article
 
Structure-based classification of tauopathies.
Shi, Yang⋅Zhang, Wenjuan⋅Yang, Yang⋅Murzin, Alexey G⋅Falcon, Benjamin⋅Kotecha, Abhay⋅van Beers, Mike⋅Tarutani, Airi⋅Kametani, Fuyuki⋅Garringer, Holly J⋅Vidal, Ruben⋅Hallinan, Grace I⋅Lashley, Tammaryn⋅Saito, Yuko⋅Murayama, Shigeo⋅Yoshida, Mari⋅Tanaka, Hidetomo⋅Kakita, Akiyoshi⋅Ikeuchi, Takeshi⋅Robinson, Andrew C⋅Mann, David M A⋅Kovacs, Gabor G⋅Revesz, Tamas⋅Ghetti, Bernardino⋅Hasegawa, Masato⋅Goedert, Michel and Scheres, Sjors H W
Nature, vol. 598, (no. 7880), pp. 359-363, October 2021. | Journal Article
 
Structure of Tau filaments in Prion protein amyloidoses.
Hallinan, Grace I⋅Hallinan, Grace I⋅Hallinan, Grace I⋅Hoq, Md Rejaul⋅Hoq, Md Rejaul⋅Ghosh, Manali⋅Ghosh, Manali⋅Vago, Frank S⋅Vago, Frank S⋅Vago, Frank S⋅Fernandez, Anllely⋅Fernandez, Anllely⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Jiang, Wen⋅Jiang, Wen⋅Jiang, Wen⋅Ghetti, Bernardino and Ghetti, Bernardino
Acta neuropathologica, June 14, 2021. | Journal Article
2020
A Striking Bone Phenotype in the Familial Danish Dementia (FDD) Tg+ Mouse
Suryadevara, Vidyani⋅Suryadevara, Vidyani⋅Krehbiel, Connor J⋅Krehbiel, Connor J⋅Vidal, Ruben⋅Vidal, Ruben⋅Willis, Monte S and Willis, Monte S
The FASEB Journal, vol. 34, (no. S1), pp. 1, 2020-04-00. | Journal Article
 
Deletion of the Microtubule‐associated protein tau (Mapt−/−) results in diastolic heart failure and altered skeletal muscle function in vivo
Rajalingam, Sahith⋅Rajalingam, Sahith⋅Kambrath, Anuradha Valiya⋅Kambrath, Anuradha Valiya⋅Vidal, Ruben⋅Vidal, Ruben⋅Willis, Monte S and Willis, Monte S
The FASEB Journal, vol. 34, (no. S1), pp. 1, 2020-04-00. | Journal Article
 
Novel tau filament fold in corticobasal degeneration
Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Tarutani, Airi⋅Tarutani, Airi⋅Tarutani, Airi⋅Tarutani, Airi⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Matsubara, Tomoyasu⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Shi, Yang⋅Shi, Yang⋅Shi, Yang⋅Shi, Yang⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Ikeuchi, Takeshi⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Murayama, Shigeo⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Hasegawa, Masato⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H W⋅Scheres, Sjors H⋅Scheres, Sjors H W and Scheres, Sjors H W
Nature, vol. 580, (no. 7802), pp. 287, 2020-04-00. | Journal Article
2019
Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration
Muhoberac, Barry B and Vidal, Ruben
Frontiers in neuroscience, vol. 13, pp. 1195, 2019-00-00. | Journal Article
 
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zivanov, Jasenko⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Crowther, R Anthony⋅Crowther, R A⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Newell, Kathy L⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Goedert, Michel⋅Scheres, Sjors H W⋅Scheres, Sjors H⋅Scheres, Sjors H W and Scheres, Sjors H W
Nature, vol. 568, (no. 7752), pp. 423, 2019-04-00. | Journal Article
 
P4‐131: TAU AS A MEDIATOR OF NEUROTOXICITY ASSOCIATED TO CEREBRAL AMYLOID ANGIOPATHY
You, Yingjian⋅You, Yingjian⋅Perkins, Abigail⋅Perkins, Abigail⋅Cisternas, Pablo⋅Cisternas, Pablo⋅Munoz, Braulio⋅Munoz, Braulio⋅Taylor, Xavier⋅Taylor, Xavier⋅You, Yanwen⋅You, Yanwen⋅Oblak, Adrian L⋅Oblak, Adrian L⋅Atwood, Brady⋅Atwood, Brady⋅Vidal, Ruben⋅Vidal, Ruben⋅Lasagna Reeves, Cristian A and Lasagna Reeves, Cristian A
Alzheimer's & Dementia, vol. 15, pp. P1326, July 2019. | Journal Article
 
Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy
You, Yingjian⋅You, Yingjian⋅You, Yingjian⋅Perkins, Abigail⋅Perkins, Abigail⋅Perkins, Abigail⋅Cisternas, Pablo⋅Cisternas, Pablo⋅Cisternas, Pablo⋅Muñoz, Braulio⋅Muñoz, Braulio⋅Muñoz, Braulio⋅Taylor, Xavier⋅Taylor, Xavier⋅Taylor, Xavier⋅You, Yanwen⋅You, Yanwen⋅You, Yanwen⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Oblak, Adrian L⋅Oblak, Adrian L⋅Oblak, Adrian L⋅Atwood, Brady K⋅Atwood, Brady K⋅Atwood, Brady K⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Lasagna-Reeves, Cristian A⋅Lasagna-Reeves, Cristian A and Lasagna-Reeves, Cristian A
Acta neuropathologica communications, vol. 7, (no. 1), pp. 26, 2019-02-26. | Journal Article
2018
Structures of filaments from Pick's disease reveal a novel tau protein fold
Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murzin, Alexey G⋅Murshudov, Garib⋅Murshudov, Garib⋅Murshudov, Garib⋅Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Crowther, R Anthony⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Scheres, Sjors H W⋅Scheres, Sjors H W⋅Scheres, Sjors H W⋅Goedert, Michel⋅Goedert, Michel and Goedert, Michel
Nature, vol. 561, (no. 7721), pp. 140O, 2018-09-00. | Journal Article
 
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
Falcon, Benjamin⋅Falcon, Benjamin⋅Falcon, Benjamin⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Zhang, Wenjuan⋅Schweighauser, Manuel⋅Schweighauser, Manuel⋅Schweighauser, Manuel⋅Murzin, Alexey⋅Murzin, Alexey⋅Murzin, Alexey⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Garringer, Holly⋅Garringer, Holly⋅Garringer, Holly⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Scheres, Sjors⋅Scheres, Sjors⋅Scheres, Sjors⋅Goedert, Michel⋅Goedert, Michel and Goedert, Michel
Acta Neuropathologica, vol. 136, (no. 5), pp. 708, 20181100. | Journal Article
2017
Amyloid and intracellular accumulation of BRI 2
Garringer, Holly J⋅Garringer, Holly J⋅Sammeta, Neeraja⋅Sammeta, Neeraja⋅Oblak, Adrian⋅Oblak, Adrian⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben
Neurobiology of aging, vol. 52, pp. 90, 2017-Apr. | Journal Article
2016
Amyloid and intracellular accumulation of BRI2.
Garringer, Holly J⋅Sammeta, Neeraja⋅Oblak, Adrian⋅Ghetti, Bernardino and Vidal, Ruben
Neurobiology of aging, vol. 52, pp. 90-97, December 29, 2016. | Journal Article
 
CONTRIBUTION OF THE NEUROPATHOLOGY LABORATORY AT INDIANA UNIVERSITY TO THE DECIPHERING OF DOMINANTLY INHERITED DEMENTIAS: 1976-2016
Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Dlouhy, Stephen⋅Dlouhy, Stephen⋅Dlouhy, Stephen⋅Dupree, Brenda⋅Dupree, Brenda⋅Dupree, Brenda⋅Epperson, Francine⋅Epperson, Francine⋅Epperson, Francine⋅Murrell, Jill⋅Murrell, Jill⋅Murrell, Jill⋅Oblak, Adrian⋅Oblak, Adrian⋅Oblak, Adrian⋅Piccardo, Pedro⋅Piccardo, Pedro⋅Piccardo, Pedro⋅Richardson, Rose⋅Richardson, Rose⋅Richardson, Rose⋅Spina, Salvatore⋅Spina, Salvatore⋅Spina, Salvatore⋅Takao, Masaki⋅Takao, Masaki⋅Takao, Masaki⋅Vidal, Ruben⋅Vidal, Ruben⋅Vidal, Ruben⋅Yamaguchi, Keiji⋅Yamaguchi, Keiji⋅Yamaguchi, Keiji⋅Young, Katherine⋅Young, Katherine and Young, Katherine
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 12, (no. 7), pp. P745, 2016. | Journal Article
 
Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy
Garringer, Holly J⋅Garringer, Holly J⋅Garringer, Holly J⋅Irimia, Jose M⋅Irimia, Jose M⋅Irimia, Jose M⋅Li, Wei⋅Li, Wei⋅Li, Wei⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Richine, Briana⋅Richine, Briana⋅Richine, Briana⋅Acton, Anthony⋅Acton, Anthony⋅Acton, Anthony⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 11, (no. 8), pp. e0161341, 2016-00-00. | Journal Article
2015
A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo
Levites, Yona⋅Levites, Yona⋅O'Nuallain, Brian⋅O'Nuallain, Brian⋅Puligedda, Rama Devudu⋅Puligedda, Rama Devudu⋅Ondrejcak, Tomas⋅Ondrejcak, Tomas⋅Adekar, Sharad P⋅Adekar, Sharad P⋅Chen, Cindy⋅Chen, Cindy⋅Cruz, Pedro E⋅Cruz, Pedro E⋅Rosario, Awilda M⋅Rosario, Awilda M⋅Macy, Sallie⋅Macy, Sallie⋅Mably, Alexandra J⋅Mably, Alexandra J⋅Walsh, Dominic M⋅Walsh, Dominic M⋅Vidal, Ruben⋅Vidal, Ruben⋅Solomon, Alan⋅Solomon, Alan⋅Brown, Daniel⋅Brown, Daniel⋅Rowan, Michael J⋅Rowan, Michael J⋅Golde, Todd E⋅Golde, Todd E⋅Dessain, Scott K and Dessain, Scott K
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 35, (no. 16), pp. 6276, 2015-Apr-22. | Journal Article
 
Systemic and cerebral iron homeostasis in ferritin knock-out mice.
Li, Wei⋅Li, Wei⋅Garringer, Holly J⋅Garringer, Holly J⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Richine, Briana⋅Richine, Briana⋅Acton, Anthony⋅Acton, Anthony⋅VanDuyn, Natalia⋅VanDuyn, Natalia⋅Muhoberac, Barry B⋅Muhoberac, Barry B⋅Irimia-Dominguez, Jose⋅Irimia-Dominguez, Jose⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Peacock, Munro⋅Peacock, Munro⋅Nass, Richard⋅Nass, Richard⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 10, (no. 1), pp. e0117435, 2015. | Journal Article
2014
Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.
Marcora, María S⋅Fernández-Gamba, Agata C⋅Avendaño, Luz A⋅Rotondaro, Cecilia⋅Podhajcer, Osvaldo L⋅Vidal, Rubén⋅Morelli, Laura⋅Ceriani, María F and Castaño, Eduardo M
Molecular neurodegeneration, vol. 9, pp. 5, January 9, 2014. | Journal Article
 
A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation.
Nishida, Katsuya⋅Nishida, Katsuya⋅Garringer, Holly J⋅Garringer, Holly⋅Futamura, Naonobu⋅Futamura, Naonobu⋅Funakawa, Itaru⋅Funakawa, Itaru⋅Jinnai, Kenji⋅Jinnai, Kenji⋅Vidal, Ruben⋅Vidal, Ruben⋅Takao, Masaki and Takao, Masaki
Journal of the neurological sciences, vol. 342, (no. 1-2), pp. 173-177, July 15, 2014. | Journal Article
 
Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice.
Pappolla, Miguel⋅Sambamurti, Kumar⋅Vidal, Ruben⋅Pacheco-Quinto, Javier⋅Poeggeler, Burkhard and Matsubara, Etsuro
Neurobiology of disease, vol. 71, pp. 215-219, November 2014. | Journal Article
2013
Abnormal iron homeostasis and neurodegeneration.
Muhoberac, Barry B⋅Muhoberac, Barry B⋅Vidal, Ruben and Vidal, Ruben
Frontiers in aging neuroscience, vol. 5, pp. 32, 2013. | Journal Article
 
Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Garringer, Holly⋅Garringer, Holly J⋅Murrell, Jill⋅Murrell, Jill⋅Sammeta, Neeraja⋅Sammeta, Neeraja⋅Gnezda, Anita⋅Gnezda, Anita⋅Ghetti, Bernardino⋅Ghetti, Bernardino⋅Vidal, Ruben and Vidal, Ruben
PloS one, vol. 8, (no. 2), pp. e56426, 2013. | Journal Article
2012
A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage
Baraibar, Martin A⋅Barbeito, Ana G⋅Muhoberac, Barry B and Vidal, Ruben
Free Radical Biology and Medicine, vol. 52, (no. 9), pp. 1692-1697, 2012. | Journal Article